Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Isabel Joan Crane"'
Autor:
Isabel Joan Crane, Reem Al-Rashoudi, Gillian Moir, Heather M. Wilson, Monther Al-Alwan, Mohamed S Al-Hajjaj
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 15, Iss 1, Pp 1-11 (2019)
Background Monocytes play an important role in immune and inflammatory diseases and monocyte subsets are predictors of disease in certain conditions. Expression of the chemokine receptors, CCR2 and CX3CR1 on monocyte subsets relates to their function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab255101cbea1e77e0b632bd3a94d5c
http://link.springer.com/article/10.1186/s13223-019-0379-5
http://link.springer.com/article/10.1186/s13223-019-0379-5
Publikováno v:
Bioscience Reports
Asthma is a chronic inflammatory disorder associated with airway hyper-responsiveness. Although a number of studies have investigated asthma at the molecular level, the molecular immune signatures associated with asthma severity or with the response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38b2cff498ee1116c05c6f979e4a9bc
https://doi.org/10.1042/bsr20180548
https://doi.org/10.1042/bsr20180548
Publikováno v:
Current eye research. 41(9)
Age-related macular degeneration (AMD) is one of the leading causes of blindness in the elderly population aged ≥60 years. Previous studies have shown that retinal pigment epithelial cell (RPE) degeneration is one of the early and crucial stages in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d8f1fab97a1f6ac6bbc2d3ed84d486
https://pubmed.ncbi.nlm.nih.gov/27015409
https://pubmed.ncbi.nlm.nih.gov/27015409
Publikováno v:
Immunology. 128:25-33
The role of CX3CR1 in regulating the function of monocytes and microglia was examined in mice in which CX3CR1 had been replaced by green fluorescent protein (GFP). Induction of experimental autoimmune uveitis (EAU) in these mice resulted in increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91d466f64067fbbb6ea9b230a74aa13
https://doi.org/10.1111/j.1365-2567.2009.03046.x
https://doi.org/10.1111/j.1365-2567.2009.03046.x
Autor:
John V. Forrester, Heping Xu, Carol Wallace, Ayyakkannu Manivannan, Isabel Joan Crane, Peter F. Sharp, Gabriel Márquez, Matthias Mack, Janet Liversidge
Publikováno v:
Journal of Leukocyte Biology. 79:435-443
Although the recruitment of T helper cell type 1 (Th1)/Th2 cells into peripheral tissues is essential for inflammation and the host response to infection, the traffic signals that enable the distinct positioning of Th1/Th2 cells are unclear. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0004eae6a6320d19e500c5da0ff8ede5
https://doi.org/10.1189/jlb.0305130
https://doi.org/10.1189/jlb.0305130
Autor:
Janet Liversidge, Ayyakkannu Manivannan, R. Dawson, Heping Xu, Isabel Joan Crane, Peter F. Sharp, Matthias Mack
Publikováno v:
The Journal of Immunology. 175:6915-6923
It is proposed that CCR2+ monocytes are specifically recruited to inflammatory sites, whereas CCR2− monocytes are recruited to normal tissue to become resident macrophages. Whether these subsets represent separate lineages, how differential traffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cbb71a3c693e0813cbaa06e5a242bc6
https://doi.org/10.4049/jimmunol.175.10.6915
https://doi.org/10.4049/jimmunol.175.10.6915
Autor:
Janet Liversidge, Ayyakkannu Manivannan, Graeme R. Lamont, Peter F. Sharp, John V. Forrester, Susan McKillop-Smith, Carol Wallace, Heping Xu, Isabel Joan Crane
Publikováno v:
European Journal of Immunology. 33:402-410
This study has enabled us to identify the influence of the chemokine, macrophage inflammatory protein-1alpha (MIP-1alpha), on leukocyte behavior at the blood-retina barrier in vivo and its link with the inflammatory process and disease pathogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e31c9c1db2419f8c838b0116995e4df
https://doi.org/10.1002/immu.200310014
https://doi.org/10.1002/immu.200310014
Autor:
John V. Forrester, Heping Xu, Keith A Goatman, Janet Liversidge, Ayyakkannu Manivannan, Peter F. Sharp, Isabel Joan Crane
Publikováno v:
Experimental Eye Research. 74:403-410
The purpose of this study is to develop a new method with which to visualize leukocyte dynamics in murine choroidal and retinal circulation. Both pigmented (B10.RIII) and non-pigmented (BALB/c) mice were used in this study. One hundred microl of 0.05
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9218d472c94087ff33ace97b5dec92
https://doi.org/10.1006/exer.2001.1134
https://doi.org/10.1006/exer.2001.1134
Publikováno v:
Immunology. 101:426-433
Chemokine production at the blood-retina barrier probably plays a critical role in determining the influx of tissue-damaging cells from the circulation into the retina during inflammation. The blood-retina barrier comprises the retinal microvascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38290787251f80f6d28250ac86cd1163
https://doi.org/10.1046/j.0019-2805.2000.01105.x
https://doi.org/10.1046/j.0019-2805.2000.01105.x
Publikováno v:
Clinical and Experimental Immunology. 115:288-293
SUMMARYGM-CSF is an important regulator of macrophage, granulocyte and dendritic cell behaviour and function. These cell types have been implicated in the retinal damage characteristic of endogenous posterior uveitis. Dendritic cells in the choroid h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c089a529b66f94d7a6407b96e9d61dbf
https://doi.org/10.1046/j.1365-2249.1999.00805.x
https://doi.org/10.1046/j.1365-2249.1999.00805.x