Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Isabel Gomez-Hurtado"'
Autor:
Irma Garcia-Martinez, Rosa Alen, Laura Pereira, Adrián Povo-Retana, Alma M. Astudillo, Ana B. Hitos, Isabel Gomez-Hurtado, Eduardo Lopez-Collazo, Lisardo Boscá, Rubén Francés, Ignacio Lizasoain, María Ángeles Moro, Jesús Balsinde, Manuel Izquierdo, Ángela M. Valverde
Publikováno v:
JHEP Reports, Vol 5, Iss 8, Pp 100756- (2023)
Background & Aims: Lipotoxicity triggers non-alcoholic fatty liver disease (NAFLD) progression owing to the accumulation of toxic lipids in hepatocytes including saturated fatty acids (SFAs), which activate pro-inflammatory pathways. We investigated
Externí odkaz:
https://doaj.org/article/976cfcba75f4439397449d4932f399d3
Autor:
Sebastian Martinez-Lopez, Enrique Angel-Gomis, Elisabet Sanchez-Ardid, Alberto Pastor-Campos, Joanna Picó, Isabel Gomez-Hurtado
Publikováno v:
Animals, Vol 13, Iss 14, p 2357 (2023)
Patients with cirrhosis present multiple physiological and immunological alterations that play a very important role in the development of clinically relevant secondary complications to the disease. Experimentation in animal models is essential to un
Externí odkaz:
https://doaj.org/article/44454ca69fb3481cb3649c5c7e15edd3
Autor:
Oriol Juanola, Paula Piñero, Isabel Gómez‐Hurtado, Esther Caparrós, Rocío García‐Villalba, Alicia Marín, Pedro Zapater, Fabián Tarín, José M. González‐Navajas, Francisco A. Tomás‐Barberán, Rubén Francés
Publikováno v:
Hepatology Communications, Vol 2, Iss 12, Pp 1610-1623 (2018)
Intestinal permeability to translocation of bacterial products is increased in cirrhosis. Regulatory T cells (Tregs) remain central to the interplay between the host and microbial milieu. We propose that Tregs are involved in promoting gut barrier in
Externí odkaz:
https://doaj.org/article/82b2a6aa3b91499fb88b47fdab865909
Autor:
Esther Caparrós, Oriol Juanola, Isabel Gómez-Hurtado, Amaya Puig-Kroger, Paula Piñero, Pedro Zapater, Raquel Linares, Fabián Tarín, Sebastián Martínez-López, Jordi Gracia-Sancho, José M. González-Navajas, Rubén Francés
Publikováno v:
Cells, Vol 9, Iss 5, p 1227 (2020)
Hepatic immune function is compromised during cirrhosis. This study investigated the immune features of liver sinusoidal endothelial cells (LSECs) in two experimental models of cirrhosis. Dendritic cells, hepatic macrophages, and LSECs were isolated
Externí odkaz:
https://doaj.org/article/bb98d19e0bff42cbb7320aff21933b7a
Autor:
Pedro Zapater, Isabel Gómez-Hurtado, Gloria Peiró, José Manuel González-Navajas, Irma García, Paula Giménez, Alba Moratalla, José Such, Rubén Francés
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43371 (2012)
BACKGROUND: Bacterial translocation is a frequent event in cirrhosis leading to an increased inflammatory response. Splanchnic adrenergic system hyperactivation has been related with increased bacterial translocation. We aim at evaluating the interac
Externí odkaz:
https://doaj.org/article/a4f0e9ce722341ee9b0e8fde167cec72
Autor:
Isabel Gómez-Hurtado, Arlette Santacruz, Gloria Peiró, Pedro Zapater, Ana Gutiérrez, Miguel Pérez-Mateo, Yolanda Sanz, Rubén Francés
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e23037 (2011)
BACKGROUND: Gut is the major source of endogenous bacteria causing infections in advanced cirrhosis. Intestinal barrier dysfunction has been described in cirrhosis and account for an increased bacterial translocation rate. HYPOTHESIS AND AIMS: We hyp
Externí odkaz:
https://doaj.org/article/eab713c73b494d30bce1381a8e5a054f