Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Isabel Freund"'
Autor:
Anna Hafner, Ulrike Kolbe, Isabel Freund, Virginia Castiglia, Pavel Kovarik, Tanja Poth, Franziska Herster, Markus A. Weigand, Alexander N. R. Weber, Alexander H. Dalpke, Tatjana Eigenbrod
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Streptococcus pyogenes is a major human pathogen causing a variety of diseases ranging from common pharyngitis to life-threatening soft tissue infections and sepsis. Microbial nucleic acids, especially bacterial RNA, have recently been recognized as
Externí odkaz:
https://doaj.org/article/dcde18935f0e4cda96fa1835e3401b9a
Autor:
Isabel Freund, Stephanie Hehlgans, Daniel Martin, Michael Ensminger, Emmanouil Fokas, Claus Rödel, Markus Löbrich, Franz Rödel
Publikováno v:
Cells, Vol 9, Iss 5, p 1235 (2020)
NIMA (never-in-mitosis gene A)-related kinase 1 (Nek1) is shown to impact on different cellular pathways such as DNA repair, checkpoint activation, and apoptosis. Its role as a molecular target for radiation sensitization of malignant cells, however,
Externí odkaz:
https://doaj.org/article/e98b33590b1545048ede298a07fe41bd
Autor:
Virginie Marchand, Florian Pichot, Kathrin Thüring, Lilia Ayadi, Isabel Freund, Alexander Dalpke, Mark Helm, Yuri Motorin
Publikováno v:
Biomolecules, Vol 7, Iss 1, p 13 (2017)
Analysis of RNA modifications by traditional physico‐chemical approaches is labor intensive, requires substantial amounts of input material and only allows site‐by‐site measurements. The recent development of qualitative and quantitative approa
Externí odkaz:
https://doaj.org/article/edf64eb77b2143c28ca5e3ae3724d0a0
Autor:
Johannes Meyer-Hamme, Riem Spielhaus, Viola B. Georgi, Martin Lücke, Sebastian Bischoff, Christine Chiriac, Cornelia Chmiel, Sina Isabel Freund, Lena Kahle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147d1543cae4fbe24f9b0ae59609d94e
https://doi.org/10.14361/9783839457924-003
https://doi.org/10.14361/9783839457924-003
Autor:
Isabel Freund, Felix C. F. Schmitt, Markus A. Weigand, Tatjana Eigenbrod, Mark Helm, Alexander H. Dalpke
Publikováno v:
RNA. 23:1344-1351
Bacterial RNA serves an important function as activator of the innate immune system. In humans bacterial RNA is sensed by the endosomal receptors TLR7 and TLR8. Differences in the posttranscriptional modification profile of prokaryotic when compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f44f980330a09e632ced3344dbcf6f
https://doi.org/10.1261/rna.061952.117
https://doi.org/10.1261/rna.061952.117
Autor:
Mark Helm, Sébastien Boutin, Florian Pichot, Holger Heine, Annika Kotter, Tim Vierbuchen, Tatjana Eigenbrod, Virginie Marchand, Yuri Motorin, Daniel K. Buhl, Isabel Freund, Alexander H. Dalpke
Publikováno v:
RNA
RNA, Cold Spring Harbor Laboratory Press, 2019, 25 (7), pp.869-880. ⟨10.1261/rna.070243.118⟩
RNA, 2019, 25 (7), pp.869-880. ⟨10.1261/rna.070243.118⟩
RNA, Cold Spring Harbor Laboratory Press, 2019, 25 (7), pp.869-880. ⟨10.1261/rna.070243.118⟩
RNA, 2019, 25 (7), pp.869-880. ⟨10.1261/rna.070243.118⟩
Bacterial RNA has emerged as an important activator of innate immune responses by stimulating Toll-like receptors TLR7 and TLR8 in humans. Guanosine 2′-O-methylation at position 18 (Gm18) in bacterial tRNA was shown to antagonize tRNA-induced TLR7/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38d41f14cc681a60e5edfa1da7bfe62
https://hal.univ-lorraine.fr/hal-02113259
https://hal.univ-lorraine.fr/hal-02113259
Autor:
Anna, Hafner, Ulrike, Kolbe, Isabel, Freund, Virginia, Castiglia, Pavel, Kovarik, Tanja, Poth, Franziska, Herster, Markus A, Weigand, Alexander N R, Weber, Alexander H, Dalpke, Tatjana, Eigenbrod
Publikováno v:
Frontiers in Immunology
Streptococcus pyogenes is a major human pathogen causing a variety of diseases ranging from common pharyngitis to life-threatening soft tissue infections and sepsis. Microbial nucleic acids, especially bacterial RNA, have recently been recognized as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d400cf422a219ba4eba25db6e156cd8
https://pubmed.ncbi.nlm.nih.gov/30846984
https://pubmed.ncbi.nlm.nih.gov/30846984