Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Isabel Fernaud-Espinosa"'
Autor:
Mite Mijalkov, Giovanni Volpe, Isabel Fernaud-Espinosa, Javier DeFelipe, Joana B. Pereira, Paula Merino-Serrais
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by a deterioration of neuronal connectivity. The pathological accumulation of tau in neurons is one of the hallmarks of AD and has been connected to the los
Externí odkaz:
https://doaj.org/article/1d034dbf4fa34ac4b7eba3dd4ccfc10a
Autor:
Isabel Vidaurre-Gallart, Isabel Fernaud-Espinosa, Nicusor Cosmin-Toader, Lidia Talavera-Martínez, Miguel Martin-Abadal, Ruth Benavides-Piccione, Yolanda Gonzalez-Cid, Luis Pastor, Javier DeFelipe, Marcos García-Lorenzo
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
The morphological analysis of dendritic spines is an important challenge for the neuroscientific community. Most state-of-the-art techniques rely on user-supervised algorithms to segment the spine surface, especially those designed for light microsco
Externí odkaz:
https://doaj.org/article/a9d734fc42bb4392ad1b7469c916f0b6
Autor:
Ivan Velasco, Pablo Toharia, Ruth Benavides-Piccione, Isabel Fernaud-Espinosa, Juan P. Brito, Susana Mata, Javier DeFelipe, Luis Pastor, Sofia Bayona
Publikováno v:
Frontiers in Neuroanatomy, Vol 14 (2020)
Knowledge about neuron morphology is key to understanding brain structure and function. There are a variety of software tools that are used to segment and trace the neuron morphology. However, these tools usually utilize proprietary formats. This cau
Externí odkaz:
https://doaj.org/article/a443fd7e33e74796b115546131a2541a
Autor:
Sergio Luengo-Sanchez, Isabel Fernaud-Espinosa, Concha Bielza, Ruth Benavides-Piccione, Pedro Larrañaga, Javier DeFelipe
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 6, p e1006221 (2018)
The dendritic spines of pyramidal neurons are the targets of most excitatory synapses in the cerebral cortex. They have a wide variety of morphologies, and their morphology appears to be critical from the functional point of view. To further characte
Externí odkaz:
https://doaj.org/article/dda99d766df04acd909840fa86223a46
Autor:
Mónica R Fernández-Cabrera, Alejandro Higuera-Matas, Isabel Fernaud-Espinosa, Javier DeFelipe, Emilio Ambrosio, Miguel Miguéns
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200950 (2018)
Derivatives from the Cannabis plant are the most commonly abused illegal substances in the world. The main psychoactive component found in the plant, Δ-9-tetrahydrocannabinol (THC), exerts its effects through the endocannabinoid system. Manipulation
Externí odkaz:
https://doaj.org/article/bab90b6c1e81448998153191261d110e
Autor:
Laura Anton-Sanchez, Pedro Larrañaga, Ruth Benavides-Piccione, Isabel Fernaud-Espinosa, Javier DeFelipe, Concha Bielza
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0180400 (2017)
We modeled spine distribution along the dendritic networks of pyramidal neurons in both basal and apical dendrites. To do this, we applied network spatial analysis because spines can only lie on the dendritic shaft. We expanded the existing 2D comput
Externí odkaz:
https://doaj.org/article/f5a4a805e8c14037974a6406791ff551
Perisomatic GABAergic innervation in the cerebral cortex is carried out mostly by basket and chandelier cells, which differentially participate in the control of pyramidal cell action potential output and synchronization. These cells establish multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f1cf50fdef4ce014da42c4691b3585
http://hdl.handle.net/10261/304761
http://hdl.handle.net/10261/304761
Autor:
Paula Merino-Serrais, Giovanni Volpe, Isabel Fernaud-Espinosa, Joana B. Pereira, Mite Mijalkov, Javier DeFelipe
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by a deterioration of neuronal connectivity. The pathological accumulation of tau in neurons is one of the hallmarks of AD and has been connected to the loss of dend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5597ea2222b09b71732f7ad12999ec00
https://doi.org/10.1038/s41598-021-91726-x
https://doi.org/10.1038/s41598-021-91726-x
Autor:
Mite Mijalkov, Joana B. Pereira, Paula Merino-Serrais, Javier DeFelipe, Isabel Fernaud-Espinosa, Giovanni Volpe
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by a deterioration of neuronal connectivity. The pathological accumulation of tau in neurons is one of the hallmarks of AD and has been connected to the loss of dend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6258629a436a4aff816fd596fe063292
https://doi.org/10.1101/2020.10.20.346718
https://doi.org/10.1101/2020.10.20.346718
Autor:
Mamen Regalado-Reyes, Javier DeFelipe, Gonzalo León-Espinosa, Isabel Fernaud-Espinosa, Ruth Benavides-Piccione
Publikováno v:
Cerebral Cortex Communications
The dendritic spines of pyramidal cells are the main postsynaptic target of excitatory glutamatergic synapses. Morphological alterations have been described in hippocampal dendritic spines during hibernation—a state of inactivity and metabolic depr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80d060554e8da487af768ae5d98d010
http://europepmc.org/articles/PMC8152943
http://europepmc.org/articles/PMC8152943