Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Isabel Fan"'
Autor:
Simina M. Boca, Saivasudha Chalasani, Talia N. Lerner, Harry S. Xenias, Isabel Fan, Adam W. Hantman, Arin Pamukcu, Qiaoling Cui, Brianna L. Berceau, Elizabeth C. Augustine, C. Savio Chan
Publikováno v:
The Journal of Neuroscience. 40:7855-7876
The external globus pallidus (GPe) is a critical node within the basal ganglia circuit. Phasic changes in the activity of GPe neurons during movement and their alterations in Parkinson's disease (PD) argue that the GPe is important in motor control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bb8c55988524eae65db6efe222234c0
https://doi.org/10.1523/jneurosci.0361-20.2020
https://doi.org/10.1523/jneurosci.0361-20.2020
Autor:
Talia N. Lerner, Isabel Fan, Harry S. Xenias, Simina M. Boca, Adam W. Hantman, Elizabeth C. Augustine, Brianna L. Berceau, Qiaoling Cui, Saivasudha Chalasani, Arin Pamukcu, C. Savio Chan
The external globus pallidus (GPe) is a critical node within the basal ganglia circuit. Phasic changes in the activity of GPe neurons during movement and their alterations in Parkinson’s disease (PD) argue that the GPe is important in motor control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f8748ede0f6cdb1c9473c21489ba9a
Autor:
Arin, Pamukcu, Qiaoling, Cui, Harry S, Xenias, Brianna L, Berceau, Elizabeth C, Augustine, Isabel, Fan, Saivasudha, Chalasani, Adam W, Hantman, Talia N, Lerner, Simina M, Boca, C Savio, Chan
Publikováno v:
J Neurosci
The external globus pallidus (GPe) is a critical node within the basal ganglia circuit. Phasic changes in the activity of GPe neurons during movement and their alterations in Parkinson's disease (PD) argue that the GPe is important in motor control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e72fac37a529086624cadd7037e1ed67
https://pubmed.ncbi.nlm.nih.gov/32868462
https://pubmed.ncbi.nlm.nih.gov/32868462
Autor:
John R. McLaughlin, Mohammad R. Akbari, Harvey A. Risch, Barry P. Rosen, Isabel Fan, Joanne Kotsopoulos, Steven A. Narod, Ping Sun, Victoria Sopik
Publikováno v:
Familial Cancer. 16:29-34
Recent studies suggest that mutations in the partner and localizer of BRCA2 (PALB2) gene may predispose to ovarian cancer. It is of importance to clarify the prevalence and penetrance of PALB2 mutations in an unselected population so that clinical re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef8c579c521765769b71b74f56e3c5b
https://doi.org/10.1007/s10689-016-9919-z
https://doi.org/10.1007/s10689-016-9919-z
Autor:
John R. McLaughlin, Taymaa May, Barry P. Rosen, Joanne Kotsopoulos, Ping Sun, Isabel Fan, Harvey A. Risch, Steven A. Narod, Joel Moody
Publikováno v:
Gynecologic Oncology. 140:42-47
Objectives After a diagnosis of ovarian cancer, positive BRCA mutation status confers a transient mortality benefit that diminishes with time. The majority of women who survive for 10–12years are effectively cured of their disease. Thus, it is impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be89a0cd1e8cde2af1dfb666a1782aea
https://doi.org/10.1016/j.ygyno.2015.11.009
https://doi.org/10.1016/j.ygyno.2015.11.009
Autor:
Anneli Loo, Harvey A. Risch, Isabel Fan, John R. McLaughlin, Steven A. Narod, Anna Ivanova, Christopher P. Crum, Barry P. Rosen, Joanne Kotsopoulos, Shelley S. Tworoger
Publikováno v:
Cancer Causes & Control. 26:601-608
Recent studies suggest that a proportion of ovarian tumors may actually originate in the distal fallopian tube. The objective of this study was to examine the relationship between dominance (a surrogate for site of origin) and survival, following a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c4b2ee073421b4343150504d1180f6
https://doi.org/10.1007/s10552-015-0547-y
https://doi.org/10.1007/s10552-015-0547-y
Autor:
John R. McLaughlin, B. Rosen, Steven A. Narod, Joanne Kotsopoulos, Ping Sun, Immaculata De Vivo, Isabel Fan, Harvey A. Risch, Jennifer Prescott
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 23:2603-2606
Background: Telomeres are essential for the maintenance of chromosomal integrity. Telomere shortening leads to genomic instability, which is hypothesized to play a role in cancer development and prognosis. No studies to date have evaluated the progno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622536e94e75bc1ffbfb860fca12da5b
https://doi.org/10.1158/1055-9965.epi-14-0885
https://doi.org/10.1158/1055-9965.epi-14-0885
Autor:
Jordan Lerner-Ellis, Harvey A. Risch, Isabel Fan, S. Bacopulos, Steven A. Narod, Amy Finch, Bruce R. Rosen, John R. McLaughlin, Linda Bradley
Publikováno v:
Clinical Genetics. 86:496-499
Genetic testing for BRCA1 and BRCA2 gene mutations, in conjunction with preventive salpingo-oophorectomy for mutation carriers, may be used to prevent a proportion of invasive ovarian cancers (‘personalized medicine’). We evaluated the potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e23374cac4f57f7ecdc4af7114d04a56
https://doi.org/10.1111/cge.12313
https://doi.org/10.1111/cge.12313
Autor:
A Risch, J R K Moody, John R. McLaughlin, Isabel Fan, Bruce R. Rosen, Ping Sun, Steven A. Narod
Publikováno v:
Clinical Genetics. 83:232-237
Several studies have reported that women with ovarian cancer and a BRCA1 or BRCA2 mutations have better survival than women with ovarian cancer and no mutation. Potential reasons for this include possible differences in histologic subtype, stage, gra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::519570dd9cccb0cb75c00a7c547a689c
https://doi.org/10.1111/j.1399-0004.2012.01906.x
https://doi.org/10.1111/j.1399-0004.2012.01906.x
Autor:
John R. McLaughlin, Shana J. Kim, Steven A. Narod, Anna Ivanova, Barry P. Rosen, Harvey A. Risch, Isabel Fan, Joanne Kotsopoulos
Publikováno v:
British Journal of Cancer
Background: Various epidemiologic factors have been shown to influence the risk of ovarian cancer development. Given the high fatality associated with this disease, it is of interest to evaluate the association of prediagnostic hormonal, reproductive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7286490824249532aa70e042c9e46185
https://pubmed.ncbi.nlm.nih.gov/28208158
https://pubmed.ncbi.nlm.nih.gov/28208158