Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Isabel Barnstorf"'
Autor:
Mariana Borsa, Niculò Barandun, Fabienne Gräbnitz, Isabel Barnstorf, Nicolas S. Baumann, Katharina Pallmer, Samira Baumann, Dominique Stark, Miroslav Balaz, Nathalie Oetiker, Franziska Wagen, Christian Wolfrum, Anna Katharina Simon, Nicole Joller, Yves Barral, Roman Spörri, Annette Oxenius
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Asymmetrical cell division helps to maintain cellular heterogeneity in the T cell compartment. Here the authors examine the differential immune responses built by naive and virtual memory T cells from young and aged individuals, and explore the effec
Externí odkaz:
https://doaj.org/article/61aae8a737c543db8b183a3356289468
Autor:
Isabel Barnstorf, Suzanne P. M. Welten, Mariana Borsa, Nicolas S. Baumann, Katharina Pallmer, Nicole Joller, Roman Spörri, Annette Oxenius
Publikováno v:
Immunity, Inflammation and Disease, Vol 8, Iss 3, Pp 249-257 (2020)
Abstract Introduction Epidemiological data suggest that persistent viral infections impair immune homeostasis and immune responsiveness. Previous studies showed that chronic virus infections negatively impact bystander T‐cell differentiation and me
Externí odkaz:
https://doaj.org/article/fe8f9d3220d148f9af28f4c72b63cf82
Autor:
Nicolas S Baumann, Suzanne P M Welten, Nicole Torti, Katharina Pallmer, Mariana Borsa, Isabel Barnstorf, Jennifer D Oduro, Luka Cicin-Sain, Annette Oxenius
Publikováno v:
PLoS Pathogens, Vol 15, Iss 5, p e1007785 (2019)
Memory T cell inflation is a process in which a subset of cytomegalovirus (CMV) specific CD8 T cells continuously expands mainly during latent infection and establishes a large and stable population of effector memory cells in peripheral tissues. Her
Externí odkaz:
https://doaj.org/article/a9d45135297e4e61995dbc712b032518
Autor:
Katharina Pallmer, Isabel Barnstorf, Nicolas S Baumann, Mariana Borsa, Stipan Jonjic, Annette Oxenius
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007725 (2019)
Besides their function in recognizing cancerous and virally infected cells, natural killer (NK) cells have the potential to shape adaptive immune responses. However, the mechanisms employed by NK cells to negatively regulate virus-specific CD8 T cell
Externí odkaz:
https://doaj.org/article/371e4f90138e4617af3375dd77cf6713
Autor:
Nicolas S Baumann, Nicole Torti, Suzanne P M Welten, Isabel Barnstorf, Mariana Borsa, Katharina Pallmer, Jennifer D Oduro, Luka Cicin-Sain, Koichi Ikuta, Burkhard Ludewig, Annette Oxenius
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1006993 (2018)
Cytomegalovirus (CMV) infection induces an atypical CD8 T cell response, termed inflationary, that is characterised by accumulation and maintenance of high numbers of effector memory like cells in circulation and peripheral tissues-a feature being su
Externí odkaz:
https://doaj.org/article/f651594890bf46f9af7dac6f35958ac8
Autor:
Isabel Barnstorf, Annette Oxenius, Yves Barral, Fabienne Gräbnitz, Niculò Barandun, Nicolas S. Baumann, Katharina Pallmer, Annika Hausmann, Alexander Yermanos, Ioana Sandu, Mariana Borsa
Publikováno v:
Science Immunology, 4 (34)
Asymmetric partitioning of fate determinants is a mechanism that contributes to T cell differentiation. However, it remains unclear whether the ability of T cells to divide asymmetrically is influenced by their differentiation state, as well as wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ce8f4edf42f34603e8944d233dde3e
https://doi.org/10.1126/sciimmunol.aav1730
https://doi.org/10.1126/sciimmunol.aav1730
Autor:
Annette Oxenius, Nicole Joller, Nicolas S. Baumann, Alexander Yermanos, Mariana Borsa, Roman Spörri, Nike Julia Krautler, Suzanne P. M. Welten, Katharina Pallmer, Isabel Barnstorf
Publikováno v:
Journal of Experimental Medicine, 216 (3)
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Barnstorf et al. demonstrate that chronic viral infections numerically reduce memory non–virus-specific (bystander) cytotoxic T lymphocytes and alter their phenotype and function. Phenotypic changes are induced by the inflammatory cytokine IL-6, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64612563d8bf7c368006f86f52790c9
https://hdl.handle.net/20.500.11850/330407
https://hdl.handle.net/20.500.11850/330407
Autor:
Mariana, Borsa, Isabel, Barnstorf, Nicolas S, Baumann, Katharina, Pallmer, Alexander, Yermanos, Fabienne, Gräbnitz, Niculò, Barandun, Annika, Hausmann, Ioana, Sandu, Yves, Barral, Annette, Oxenius
Publikováno v:
Science immunology. 4(34)
Asymmetric partitioning of fate determinants is a mechanism that contributes to T cell differentiation. However, it remains unclear whether the ability of T cells to divide asymmetrically is influenced by their differentiation state, as well as wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ab1185e328bbfcbf421c0672deaed83
https://pubmed.ncbi.nlm.nih.gov/30979796
https://pubmed.ncbi.nlm.nih.gov/30979796
Autor:
Christoph H. Tripp, Isabel Barnstorf, Guido Wollmann, Janine Kimpel, Dorothee Holm-von Laer, Iris Koske, Nikolaus Romani, Patrizia Stoitzner, Zoltán Bánki
Publikováno v:
Cancer Immunology Research. 4:A038-A038
VSV-GP, a novel chimeric Vesicular Stomatitis Virus (VSV) pseudotyped with the glycoprotein of the lymphocytic choriomeningitis virus represents a promising oncolytic virus (OV) that preferentially targets and kills cancer cells. Release of tumor ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e7f837e092e6756a355a4386dbf890c
https://doi.org/10.1158/2326-6066.imm2016-a038
https://doi.org/10.1158/2326-6066.imm2016-a038
Autor:
Nicolas S. Baumann, Annette Oxenius, Franziska Wagen, Roman Spörri, Yves Barral, Anna Katharina Simon, Dominique Stark, Nathalie Oetiker, Mariana Borsa, Fabienne Gräbnitz, Miroslav Balaz, Katharina Pallmer, Isabel Barnstorf, Christian Wolfrum, Nicole Joller, Samira Baumann, Niculò Barandun
Publikováno v:
Nature Communications, 12 (1)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Efficient immune responses rely on heterogeneity, which in CD8+ T cells, amongst other mechanisms, is achieved by asymmetric cell division (ACD). Here we find that ageing, known to negatively impact immune responses, impairs ACD in murine CD8+ T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0a9cb46660ed8314b4156839013126