Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Isabel Aparici-Espert"'
Publikováno v:
Molecules, Vol 23, Iss 3, p 673 (2018)
Photosensitization by drugs is a problem of increasing importance in modern life. This phenomenon occurs when a chemical substance in the skin is exposed to sunlight. Photosensitizing drugs are reported to cause severe skin dermatitis, and indeed, it
Externí odkaz:
https://doaj.org/article/42a2689a66724b61996299c071ef364d
Autor:
Isabel Aparici-Espert, Antonio Francés-Monerris, Miguel A. Miranda, Gemma M. Rodríguez-Muñiz, Virginie Lhiaubet-Vallet, Daniel Roca-Sanjuán
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
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The chemical fate of radical intermediates is relevant to understand the biological effects of radiation and to explain formation of DNA lesions. A direct approach to selectively generate the putative reactive intermediates is based on the irradiatio
Autor:
Isabel Aparici-Espert, Zhiping Yan, David Lee Phillips, Miguel A. Miranda, Virginie Lhiaubet-Vallet, Ruixue Zhu, Ming-De Li
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
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[EN] Imatinib is a synthetic tyrosinase inhibitor that is employed for the treatment of some kinds of human cancer. This drug has a low phototoxicity towards DNA, but its pyridylpyrimidine (1) fragment by itself exhibits significant phototoxicitiy. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4207c0fed03db204b06a148539e5c75
https://doi.org/10.1002/chem.201800716
https://doi.org/10.1002/chem.201800716
Autor:
Miguel A. Miranda, Inmaculada Andreu, Isabel Aparici-Espert, Guillermo Garcia-Lainez, Virginie Lhiaubet-Vallet
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
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ACS CHEMICAL BIOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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ACS CHEMICAL BIOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
[EN] In this work, the attention is focused on UVA-photosensitized reactions triggered by a DNA chromophore-containing lesion, namely 5-formyluracil. This is a major oxidatively generated lesion that exhibits an enhanced light absorption in the UVB-U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1cca3e590418aaea53932075e0a980
http://hdl.handle.net/10251/143885
http://hdl.handle.net/10251/143885
Autor:
Isabel Aparici-Espert, Virginie Lhiaubet-Vallet, Miguel A. Miranda, Cecilia Paris, Maria Consuelo Cuquerella
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
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instname
[EN] Using a sunscreen-based photocage, we have demonstrated that it is possible to prevent photodegradation of a bioactive compound and to achieve its controlled photorelease. The concept has been proven linking avobenzone, one of the most important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d9a7d06184f269b43a17a477480d95
https://hdl.handle.net/10251/102329
https://hdl.handle.net/10251/102329