Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Isabel Alvarado Cruz"'
Autor:
Elizabeth Jose, Woody March-Steinman, Bryce A. Wilson, Lisa Shanks, Chance Parkinson, Isabel Alvarado-Cruz, Joann B. Sweasy, Andrew L. Paek
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Oxidative stress from excess H2O2 activates transcription factors that restore redox balance and repair oxidative damage. Although many transcription factors are activated by H2O2, it is unclear whether they are activated at the same H2O2 co
Externí odkaz:
https://doaj.org/article/a98eff01ebe8481e85f36c4b70106900
Autor:
Carolina Lerma-Treviño, Leticia Hernández-Cadena, Jorge Octavio Acosta-Montes, Georgina Hernández-Montes, Isabel Alvarado-Cruz, Isabelle Romieu, Albino Barraza-Villarreal
Publikováno v:
Toxics, Vol 12, Iss 7, p 476 (2024)
Exposure to arsenic (As) is a public health problem associated with cancer (skin and colon) and it has been reported that epigenetic changes may be a potential mechanism of As carcinogenesis. It is pertinent to evaluate this process in genes that hav
Externí odkaz:
https://doaj.org/article/17122b822ae444abb55c354c834a9680
Autor:
Luis Terrazas-Salgado, Alejandra García-Gasca, Miguel Betancourt-Lozano, Raúl Llera-Herrera, Isabel Alvarado-Cruz, Beatriz Yáñez-Rivera
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Zebrafish (Danio rerio) is a well-established vertebrate model in ecotoxicology research that responds to a wide range of xenobiotics such as pesticides, drugs, and endocrine-disrupting compounds. The epigenome can interact with the environment and t
Externí odkaz:
https://doaj.org/article/bedb37c00d9e408cb17cbb0e6c0974fe
Autor:
Russell A. Morales-Rubio, Isabel Alvarado-Cruz, Natalia Manzano-León, Maria-de-los-Angeles Andrade-Oliva, Marisela Uribe-Ramirez, Betzabet Quintanilla-Vega, Álvaro Osornio-Vargas, Andrea De Vizcaya-Ruiz
Publikováno v:
Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-16 (2019)
Abstract Background Exposure to particulate matter (PM) is associated with an adverse intrauterine environment, which can promote adult cardiovascular disease (CVD) risk. Ultrafine particles (UFP) (small size and large surface area/mass ratio) are sy
Externí odkaz:
https://doaj.org/article/58e6ee0b7d0e4acd9a66c33636719ccb
Autor:
Isabel Alvarado-Cruz, Jorge A. Alegría-Torres, Nereida Montes-Castro, Octavio Jiménez-Garza, Betzabet Quintanilla-Vega
Publikováno v:
Annals of Global Health, Vol 84, Iss 2, Pp 212-224 (2018)
Background: Children are susceptible to environmental contaminants and are at risk of developing diseases, more so if the exposure begins at an early age. Epidemiological studies have postulated the hypothesis of the fetal origin of disease, which is
Externí odkaz:
https://doaj.org/article/a3bc559b87cb4fdc8591ea6f4a750dd8
Autor:
Luis Terrazas-Salgado, Beatriz Yáñez-Rivera, Raúl Llera-Herrera, Alejandra García-Gasca, Isabel Alvarado-Cruz, Miguel Betancourt-Lozano
Publikováno v:
Journal of Environmental Science and Health, Part B. 57:775-785
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1315d7f489bdcd10ed0508678aa53503
https://doi.org/10.1080/03601234.2022.2115780
https://doi.org/10.1080/03601234.2022.2115780
Autor:
Luis Terrazas-Salgado, Alejandra García-Gasca, Miguel Betancourt-Lozano, Raúl Llera-Herrera, Isabel Alvarado-Cruz, Beatriz Yáñez-Rivera
Publikováno v:
Frontiers in cell and developmental biology. 10
Zebrafish (Danio rerio) is a well-established vertebrate model in ecotoxicology research that responds to a wide range of xenobiotics such as pesticides, drugs, and endocrine-disrupting compounds. The epigenome can interact with the environment and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3535b408edb08438f8de9707eb9d1887
https://pubmed.ncbi.nlm.nih.gov/35281093
https://pubmed.ncbi.nlm.nih.gov/35281093
Autor:
Betzabet Quintanilla-Vega, Isabel Alvarado-Cruz, I. García-Aguiar, N. Montes-Castro, C. Escamilla-Núñez, L. Torres-Sánchez, L.M. Del Razo, Angel Barrera-Hernández
Publikováno v:
Journal of Trace Elements in Medicine and Biology. 55:110-120
The developmental period in utero is a critical window for environmental exposure. Epigenetic fetal programming via DNA methylation is a pathway through which metal exposure influences the risk of developing diseases later in life. Genetic damage rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d863eada67041ecec4d3369353ebdb
https://doi.org/10.1016/j.jtemb.2019.06.014
https://doi.org/10.1016/j.jtemb.2019.06.014
Differential immunomodulatory effect of PARP inhibition in BRCA1 deficient and competent tumor cells
Autor:
Yu Shyr, Yong Kong, Shuangge Ma, Hailey Wyatt, Kaylyn Clairmont, Victoria Quintana, Shilin Zhao, Kurt A. Schalper, Zachary D. Nagel, Rithy Meas, Patricia LoRusso, Sebastian Oeck, Isabel Alvarado-Cruz, Angelo Porciuncula, Ying Zhu, Daniel J. Laverty, Michael Krauthammer, Mariam M. Mahmoud, Joann B. Sweasy, Mohammed Khan
Publikováno v:
Biochem Pharmacol
Poly-ADP-ribose polymerase (PARP) inhibitors are active against cells and tumors with defects in homology-directed repair as a result of synthetic lethality. PARP inhibitors (PARPi) have been suggested to act by either catalytic inhibition or by PARP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be385c651532db58837877fc5a7fae6
https://www.ncbi.nlm.nih.gov/pubmed/33285109
https://www.ncbi.nlm.nih.gov/pubmed/33285109
Autor:
Tania Rahim, R. Stephen Lloyd, Joann B. Sweasy, Melis Kant, Alireza G. Senejani, Madison Levinson, Stephen E. Maher, Miral Dizdaroglu, Caroline J. Zeiss, Rithy Meas, Marina Cardó-Vila, Sesha L. A. Paluri, Kaylyn Clairmont, Michael Kashgarian, Isabel Alvarado-Cruz, Pawel Jaruga, Alfred L. M. Bothwell, Erdem Coskun, Matthew J. Burak
Publikováno v:
DNA Repair (Amst)
The Polb gene encodes DNA polymerase beta (Pol β), a DNA polymerase that functions in base excision repair (BER) and microhomology-mediated end-joining. The Pol β-Y265C protein exhibits low catalytic activity and fidelity, and is also deficient in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ed4da1a3471381db99c441029e0b4f
https://pubmed.ncbi.nlm.nih.gov/34186496
https://pubmed.ncbi.nlm.nih.gov/34186496