Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Isabel Alcobia"'
Autor:
Ricardo Laranjeiro, Isabel Alcobia, Hélia Neves, Andreia C Gomes, Pedro Saavedra, Catarina C Carvalho, António Duarte, António Cidadão, Leonor Parreira
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34553 (2012)
BackgroundIn mouse embryos, homozygous or heterozygous deletions of the gene encoding the Notch ligand Dll4 result in early embryonic death due to major defects in endothelial remodeling in the yolk sac and embryo. Considering the close developmental
Externí odkaz:
https://doaj.org/article/b3031ee285004764ba16000a8b3e42c2
Autor:
Isabel Alcobia, Margarida Gama-Carvalho, Leonor Magalhães, Vitor Proa, Domingos Henrique, Hélia Neves
The thymus is a conserved organ among vertebrates, derived from the endoderm of distinct pharyngeal pouches (PP), whose location and number vary in different species. Together with reports of sporadic ectopic thymus locations in mice and humans, this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4df979e3d025cdebf2d26c437731188f
https://doi.org/10.1101/2022.03.09.483697
https://doi.org/10.1101/2022.03.09.483697
Autor:
Joana Clara Silva, Hélia Neves, Marta Figueiredo, Vitor Proa, António Cidadão, Isabel Alcobia, Rita Zilhão, Ana Sofia Santos
Publikováno v:
Developmental Biology. 418:268-282
The avian thymus and parathyroids (T/PT) common primordium derives from the endoderm of the third and fourth pharyngeal pouches (3/4PP). The molecular mechanisms that govern T/PT development are not fully understood. Here we study the effects of Notc
Autor:
Bruno A. Cardoso, Isabel Alcobia, João T. Barata, Teresa L. Serafim, Padma Akkapeddi, Rita Fragoso, Mariana L. Oliveira, Afonso R. M. Almeida
Publikováno v:
Cellular Signalling
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological cancer that arises from clonal expansion of transformed T-cell precursors. In this review we summarize the current knowledge on the external stimuli and cell-intrinsic lesions
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Segundo a literatura, adesão terapêutica à medicação antirretroviral é fundamental para a manutenção do estado de saúde e melhoria da qualidade de vida nas pessoas com o Vírus da Imunodeficiência Humana (VIH). A falta de apoio socioeconóm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e9d8915255cfc70d5fe9d8429f851c84
https://hdl.handle.net/10400.26/18967
https://hdl.handle.net/10400.26/18967
Autor:
Hélia Neves, Antonio Duarte, Leonor Parreira, Andreia C. Gomes, Isabel Alcobia, Pedro Saavedra, Ricardo Laranjeiro, António Cidadão, C.C. Carvalho
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34553 (2012)
PLoS ONE
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS ONE
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Background: In mouse embryos, homozygous or heterozygous deletions of the gene encoding the Notch ligand Dll4 result in early embryonic death due to major defects in endothelial remodeling in the yolk sac and embryo. Considering the close development
Autor:
Pedro Saavedra, Isabel Alcobia, Andreia C. Gomes, Ricardo Laranjeiro, Sónia Oliveira, António Cidadão, Leonor Parreira
Publikováno v:
Cells, tissues, organs. 193(4)
We portrayed the Notch system in embryonic stem cell (ESC)-derived embryoid bodies (EBs) differentiating under the standard protocols used to assess yolk sac (YS) hematopoiesis in vitro. Notch receptors and Notch ligands were detected in virtually al
Publikováno v:
Experimental cell research. 290(2)
It is believed that pericentromeric heterochromatin may play a major role in the epigenetic regulation of gene expression. We have previously shown that centromeres in human peripheral blood cells aggregate into distinct “myeloid” and “lymphoid
Publikováno v:
CIÊNCIAVITAE
ResearcherID
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2f19456e1ebec62f0561fddf94d16a53
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000186537100591&KeyUID=WOS:000186537100591
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000186537100591&KeyUID=WOS:000186537100591
Publikováno v:
CIÊNCIAVITAE
ResearcherID
Scopus-Elsevier
ResearcherID
Scopus-Elsevier
It is believed that the 3-dimensional organization of centromeric heterochromatin in interphase may be of functional relevance as an epigenetic mechanism for the regulation of gene expression. Accordingly, a likely possibility is that the centromeres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befd9b90701c8a918119059d92ea8afd
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000085564700012&KeyUID=WOS:000085564700012
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000085564700012&KeyUID=WOS:000085564700012