Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Isabel A. Hutchings"'
Autor:
Alan B. Rickinson, Wolfgang Hammerschmidt, Rosemary J. Tierney, Isabel A. Hutchings, Andrew I. Bell, Claire Shannon-Lowe, Markus Altmann, Jasdeep Nagra
Publikováno v:
J. Virol. 81, 10092-10100 (2007)
Epstein-Barr virus (EBV) can infect various cell types but limits its classical growth-transforming function to B lymphocytes, the cells in which it persists in vivo. Transformation initiates with the activation of Wp, a promoter present as tandemly
Autor:
Alan B. Rickinson, Julianna Stylianou, Gemma L. Kelly, Rosemary J. Tierney, Isabel A. Hutchings, Andrew I. Bell
Publikováno v:
Journal of Virology. 80:10700-10711
The Epstein-Barr virus (EBV) latent cycle promoter Wp, present in each tandemly arrayed copy of the BamHI W region in the EBV genome, drives expression of the EB viral nuclear antigens (EBNAs) at the initiation of virus-induced B-cell transformation.