Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Isaac M. Oderberg"'
Autor:
Isaac M. Oderberg, Wolfram Goessling
Publikováno v:
JCI Insight, Vol 8, Iss 1 (2023)
The liver is a highly regenerative organ, yet the presence of a dedicated stem cell population remains controversial. Here, we interrogate a severe hepatocyte injury model in adult zebrafish to define that regeneration involves a stem cell population
Externí odkaz:
https://doaj.org/article/5f17b3f6bf334c96abb407bffd420761
Autor:
Olivia Weeks, Bess M. Miller, Brian J. Pepe-Mooney, Isaac M. Oderberg, Scott H. Freeburg, Colton J. Smith, Trista E. North, Wolfram Goessling
Publikováno v:
JCI Insight, Vol 7, Iss 23 (2022)
Ethanol (EtOH) is a commonly encountered teratogen that can disrupt organ development and lead to fetal alcohol spectrum disorders (FASDs); many mechanisms of developmental toxicity are unknown. Here, we used transcriptomic analysis in an established
Externí odkaz:
https://doaj.org/article/6dbb93bc4e19410f9eeec00de2e88288
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 3, Pp 347-363 (2019)
The incidence of hepatocellular carcinoma (HCC) and the mortality resulting from HCC are both increasing. Most patients with HCC are diagnosed at advanced stages when curative treatments are impossible. Current drug therapy extends mean overall survi
Externí odkaz:
https://doaj.org/article/4820b0d51c544a759c773b3ae0ae8085
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009466 (2021)
Planarians are flatworms and can perform whole-body regeneration. This ability involves a mechanism to distinguish between anterior-facing wounds that require head regeneration and posterior-facing wounds that require tail regeneration. How this head
Externí odkaz:
https://doaj.org/article/123d26313eb5410fb3ef05a734fa755c
Publikováno v:
Hepatology
The liver is innervated by autonomic and sensory fibers of the sympathetic and parasympathetic nervous systems that regulate liver function, regeneration, and disease. Although the importance of the hepatic nervous system in maintaining and restoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f65f709781c710a6f17acc5b191c6f
https://doi.org/10.1002/hep.32055
https://doi.org/10.1002/hep.32055
Autor:
Isaac M. Oderberg, Arkadi Schwartz, Paul J. Wrighton, Wolfram Goessling, Gabriel D. Bossé, Daan Kloosterman, Sebastian Akle, Isaac Adatto, Isabelle Iversen, Kyle A. LaBella, Pouneh K. Fazeli, Matthew L. Steinhauser, Yariv Houvras, Randall T. Peterson, Allison Tsomides, Sahar Tavakoli, Michael E. Charness, Olivia Weeks
Publikováno v:
The Journal of Clinical Investigation
Prenatal alcohol exposure (PAE) affects at least 10% of newborns globally and leads to the development of fetal alcohol spectrum disorders (FASDs). Despite its high incidence, there is no consensus on the implications of PAE on metabolic disease risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2fa0364e864932afc5c51d92619ada
https://doi.org/10.1172/jci132139
https://doi.org/10.1172/jci132139
Autor:
Olivia Weeks, Bess M. Miller, Brian J. Pepe-Mooney, Isaac M. Oderberg, Scott H. Freeburg, Colton J. Smith, Trista E. North, Wolfram Goessling
Publikováno v:
JCI insight. 7(23)
Ethanol (EtOH) is a commonly encountered teratogen that can disrupt organ development and lead to fetal alcohol spectrum disorders (FASDs); many mechanisms of developmental toxicity are unknown. Here, we used transcriptomic analysis in an established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a4af877dece80f3c11ea9985a7f6af
https://pubmed.ncbi.nlm.nih.gov/36477359
https://pubmed.ncbi.nlm.nih.gov/36477359
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 3, Pp 347-363 (2019)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
The incidence of hepatocellular carcinoma (HCC) and the mortality resulting from HCC are both increasing. Most patients with HCC are diagnosed at advanced stages when curative treatments are impossible. Current drug therapy extends mean overall survi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476acdf5f09ee572aaef150e6ad48289
http://www.sciencedirect.com/science/article/pii/S2352345X19300633
http://www.sciencedirect.com/science/article/pii/S2352345X19300633
Autor:
Isaac M. Oderberg, Wolfram Goessling
Publikováno v:
J Vis Exp
Liver failure is one of the leading causes of death worldwide, and mortality from chronic liver disease is rising sharply in the United States. Healthy livers are capable of regenerating from toxic damage, but in advanced liver disease, the natural a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221a7e8bc76e3c67f13a5850d91c8213
https://doi.org/10.3791/62349
https://doi.org/10.3791/62349
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 3, p e1009466 (2021)
PLoS Genetics, Vol 17, Iss 3, p e1009466 (2021)
Planarians are flatworms and can perform whole-body regeneration. This ability involves a mechanism to distinguish between anterior-facing wounds that require head regeneration and posterior-facing wounds that require tail regeneration. How this head
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf47de9740b3f880e2475c626cca8d6
http://europepmc.org/articles/PMC8057570
http://europepmc.org/articles/PMC8057570