Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Isaac Lynch"'
Autor:
Jennifer L. Leiting, Stephen J. Murphy, John R. Bergquist, Matthew C. Hernandez, Tommy Ivanics, Amro M. Abdelrahman, Lin Yang, Isaac Lynch, James B. Smadbeck, Sean P. Cleary, David M. Nagorney, Michael S. Torbenson, Rondell P. Graham, Lewis R. Roberts, Gregory J. Gores, Rory L. Smoot, Mark J. Truty
Publikováno v:
JHEP Reports, Vol 2, Iss 2, Pp - (2020)
Background & Aims: Biliary tract tumors are uncommon but highly aggressive malignancies with poor survival outcomes. Due to their low incidence, research into effective therapeutics has been limited. Novel research platforms for pre-clinical studies
Externí odkaz:
https://doaj.org/article/7980e146ca6b421f8c918ff7b4197c82
Autor:
Feda H Hamdan, Amro M Abdelrahman, Ana Patricia Kutschat, Xin Wang, Thomas L Ekstrom, Nidhi Jalan-Sakrikar, Catherine Wegner Wippel, Negar Taheri, Liezel Tamon, Waltraut Kopp, Joana Aggrey-Fynn, Aditya V Bhagwate, Roberto Alva-Ruiz, Isaac Lynch, Jennifer Yonkus, Robyn Laura Kosinsky, Jochen Gaedcke, Stephan A Hahn, Jens T Siveke, Rondell Graham, Zeynab Najafova, Elisabeth Hessmann, Mark J Truty, Steven A Johnsen
Publikováno v:
Gut. 72:1174-1185
ObjectivePancreatic ductal adenocarcinoma (PDAC) displays a remarkable propensity towards therapy resistance. However, molecular epigenetic and transcriptional mechanisms enabling this are poorly understood. In this study, we aimed to identify novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96374b93a79c5dd82550264fe249126b
https://doi.org/10.1136/gutjnl-2022-328154
https://doi.org/10.1136/gutjnl-2022-328154
Autor:
Danielle M. Carlson, Amro Abdelrahman, Alessandro Fogliati, Isaac Lynch, Jennifer Tomlinson, Mark Truty, Rory Smoot
Publikováno v:
Cancer Research. 83:2237-2237
Introduction: Cholangiocarcinoma (CCA) is a highly lethal, and biologically heterogenous malignancy arising from the biliary tree. With only moderate responses to cytotoxic chemotherapy and despite the development of targeted therapies, treatment suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae4fed98b0c5b23869c2aea906e253f8
https://doi.org/10.1158/1538-7445.am2023-2237
https://doi.org/10.1158/1538-7445.am2023-2237
Autor:
Rondell P. Graham, Michael Torbenson, Isaac Lynch, Lewis R. Roberts, Gregory J. Gores, Rory L. Smoot, Sean P. Cleary, Mark J. Truty, John R. Bergquist, David M. Nagorney, Matthew C. Hernandez, Tommy Ivanics, James B. Smadbeck, Amro M. Abdelrahman, Stephen J. Murphy, Jennifer L. Leiting, Lin Yang
Publikováno v:
JHEP Reports
JHEP Reports, Vol 2, Iss 2, Pp-(2020)
JHEP Reports, Vol 2, Iss 2, Pp-(2020)
Background & Aims Biliary tract tumors are uncommon but highly aggressive malignancies with poor survival outcomes. Due to their low incidence, research into effective therapeutics has been limited. Novel research platforms for pre-clinical studies a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9c080e5ea0fb426b281a8c38e3cc87
https://doi.org/10.1016/j.jhepr.2020.100068
https://doi.org/10.1016/j.jhepr.2020.100068