Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Isaac J. Perron"'
Autor:
Isaac J Perron, Brendan T Keenan, Karthikeyani Chellappa, Nicholas F Lahens, Nicole L Yohn, Keith R Shockley, Allan I Pack, Sigrid C Veasey
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196743 (2018)
BACKGROUND AND AIMS:Associated with numerous metabolic and behavioral abnormalities, obesity is classified by metrics reliant on body weight (such as body mass index). However, overnutrition is the common cause of obesity, and may independently contr
Externí odkaz:
https://doaj.org/article/cc8a41288d2543959c96f7cae511ac33
Autor:
Jason Robert Gerstner, George eSmith, Olivia eLenz, Isaac J Perron, Russell J Buono, Thomas N Ferraro
Publikováno v:
Frontiers in Systems Neuroscience, Vol 8 (2014)
The epilepsies are a heterogeneous group of neurological diseases defined by the occurrence of unprovoked seizures which, in many cases, are correlated with diurnal rhythms. In order to gain insight into the biological mechanisms controlling this phe
Externí odkaz:
https://doaj.org/article/f1e926e0cbd647be81d6beeb00d5f582
Autor:
Isaac J. Perron, Bridgin G. Lee, Julie A. Blendy, Sangwon F. Kim, Sunghee Jin, Julia K. Brynildsen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Cigarette smoking is the leading cause of preventable disease and death in the United States. Severe withdrawal symptoms are the reason most people have a hard time quitting smoking. AMP-activated protein kinase (AMPK) is a master regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65575334b2c9224bfdc5656d3d87261
https://doi.org/10.1073/pnas.1707047115
https://doi.org/10.1073/pnas.1707047115
Publikováno v:
Aging Cell
The prevalence of obesity increases with age in humans and in rodents. Age‐related obesity is characterized by leptin resistance and associated with heightened risk of metabolic disorders. However, the effect of leptin resistance per se has been di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7a934ae89e41fcde99fad96475dd94
http://europepmc.org/articles/PMC6516176
http://europepmc.org/articles/PMC6516176
Autor:
Cole S. Purdy, Amber L. Alhadeff, Denise M. DeFelice, Karthikeyani Chellappa, Yajing Peng, Sarmistha Mukherjee, Jay L. Tomasiewicz, Matthew H. Wakai, Emma Meyer, Dudley W. Lamming, Mohammed I. Alotaibi, Georgios K. Paschos, J. Nicholas Betley, Isaac J. Perron, Amy Lin, Rebecca Yao, Luigi Puglielli, Joseph A. Baur, Sebastian I. Arriola Apelo, Jacqueline A. Brinkman, Mark Morrison, Kathryn A. Carbajal
Publikováno v:
Aging Cell
The mechanistic target of rapamycin (mTOR) is an evolutionarily conserved protein kinase that regulates growth and metabolism. mTOR is found in two protein complexes, mTORC1 and mTORC2, that have distinct components and substrates and are both inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994cbabcf8d0e017a2f6531c34af4b8a
https://pubmed.ncbi.nlm.nih.gov/31373126
https://pubmed.ncbi.nlm.nih.gov/31373126
Autor:
Jason R. Gerstner, Samantha M. Riedy, Allan I. Pack, Takeo Yoshikawa, Marcos G. Frank, Raymond J. Galante, Isaac J. Perron, Hans P. A. Van Dongen, Yuji Owada, Jerry C. P. Yin, Hiroshi Kadotani, Kaitlin Dickinson
Publikováno v:
Science Advances
The astrocyte brain-type fatty acid binding protein FABP7 regulates sleep consolidation across phylogeny.
Sleep is found widely in the animal kingdom. Despite this, few conserved molecular pathways that govern sleep across phyla have been descri
Sleep is found widely in the animal kingdom. Despite this, few conserved molecular pathways that govern sleep across phyla have been descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62fe8f477728011dd9f5144f4b767049
http://europepmc.org/articles/PMC5381954
http://europepmc.org/articles/PMC5381954
Autor:
Isaac J. Perron, Alan J. Park, Christopher G. Vecsey, Mathieu E. Wimmer, Peter Meerlo, Robbert Havekes, Ted Abel
Publikováno v:
Sleep, 36(4), 601-607. Oxford University Press
Study Objectives: Gentle handling is commonly used to perform brief sleep deprivation in rodents. It was recently reported that daily acclimation handling, which is often used before behavioral assays, causes alterations in sleep, stress, and levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f79b5b16dd50d831549d5c0e7dfbfc5
https://doi.org/10.5665/sleep.2556
https://doi.org/10.5665/sleep.2556
Autor:
Allan I. Pack, Brendan T. Keenan, Karthikeyani Chellappa, Sigrid C. Veasey, Nicole L. Yohn, Nicholas F. Lahens, Isaac J. Perron, Keith R. Shockley
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 5, p e0196743 (2018)
PLoS ONE, Vol 13, Iss 5, p e0196743 (2018)
Background and aims Associated with numerous metabolic and behavioral abnormalities, obesity is classified by metrics reliant on body weight (such as body mass index). However, overnutrition is the common cause of obesity, and may independently contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07677b9ea7bb5fb4709e10c9bf222fe8
https://doi.org/10.1371/journal.pone.0196743
https://doi.org/10.1371/journal.pone.0196743
Study objectives Excessive daytime sleepiness commonly affects obese people, even in those without sleep apnea, yet its causes remain uncertain. We sought to determine whether acute dietary changes could induce or rescue wake impairments independent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd64e9088cdec18d50f97c8960f70a4d
https://europepmc.org/articles/PMC4667395/
https://europepmc.org/articles/PMC4667395/
Autor:
Hiroshi Kadotani, Marcos G. Frank, H Van Dongen, Allan I. Pack, K Dickinson, Samantha M. Riedy, Jerry C. P. Yin, Takeo Yoshikawa, Isaac J. Perron, Jason R. Gerstner, Yuji Owada
Publikováno v:
Sleep. 40:A5-A5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1a356bab3446ca138c91a7be90d7fcd
https://doi.org/10.1093/sleepj/zsx050.012
https://doi.org/10.1093/sleepj/zsx050.012