Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Isaac J, Dripps"'
Autor:
Zachariah Bertels, Isaac J. Dripps, Pal Shah, Laura S. Moye, Alycia F. Tipton, Kendra Siegersma, Amynah A. Pradhan
Publikováno v:
Neurobiology of Pain, Vol 12, Iss , Pp 100099- (2022)
Migraine is one of the most common pain disorders and causes disability in millions of people every year. Delta opioid receptors (DOR) have been identified as a novel therapeutic target for migraine and other headache disorders. DORs are present in b
Externí odkaz:
https://doaj.org/article/b44729b7206341089a0216b39e2458d8
Autor:
Keith M. Olson, Todd M. Hillhouse, Gwendolyn E. Burgess, Joshua L. West, James E. Hallahan, Isaac J. Dripps, Allison G. Ladetto, Kenner C. Rice, Emily M. Jutkiewicz, John R. Traynor
Publikováno v:
J Pharmacol Exp Ther
Major depressive disorder is a highly common disorder, with a lifetime prevalence in the United States of approximately 21%. Traditional antidepressant treatments are limited by a delayed onset of action and minimal efficacy in some patients. Ketamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5714b94c2515eb3171dbf241ed746d
https://pubmed.ncbi.nlm.nih.gov/36456196
https://pubmed.ncbi.nlm.nih.gov/36456196
Autor:
Kathryn E. Livingston, Emily M. Jutkiewicz, Alexander Disney, Stephen M. Husbands, Ruizhuo Chen, John R. Traynor, Kenner C. Rice, Amanda M. Shafer, Isaac J. Dripps
Publikováno v:
J Pharmacol Exp Ther
δ-Opioid receptor (δ-receptor) agonists produce antihyperalgesia, antidepressant-like effects, and convulsions in animals. However, the role of agonist efficacy in generating different δ-receptor–mediated behaviors has not been thoroughly invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc1cd61690216c19b61022c3d6328b7
https://doi.org/10.1124/jpet.119.262717
https://doi.org/10.1124/jpet.119.262717
Autor:
Areeb Akbari, Amynah A. Pradhan, Ana Vicente-Sánchez, Alycia F Tipton, Isaac J. Dripps, Heba Akbari, Emily M. Jutkiewicz
Publikováno v:
British Journal of Pharmacology. 175:3050-3059
Background and purpose Opioid δ receptor agonists are potent antihyperalgesics in chronic pain models, but tolerance develops after prolonged use. Previous evidence indicates that distinct forms of tolerance occur depending on the internalization pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc435c9d467104836f78356cfd06e6e
https://doi.org/10.1111/bph.14353
https://doi.org/10.1111/bph.14353
Autor:
Kenner C. Rice, John R. Traynor, Emily M. Jutkiewicz, Isaac J. Dripps, Brett T. Boyer, Richard R. Neubig
Publikováno v:
British Journal of Pharmacology. 175:891-901
Background and Purpose G protein-coupled receptors exist in multiple conformations that can engage distinct signaling mechanisms which in turn may lead to diverse behavioral outputs. In rodent models, activation of the delta opioid receptor (δ-recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5158e257ee7d69b65f3ff1acefe8663
https://doi.org/10.1111/bph.14131
https://doi.org/10.1111/bph.14131
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aa188f3b7a294c6dd7dc08306420449
https://doi.org/10.1096/fasebj.2019.33.1_supplement.666.5
https://doi.org/10.1096/fasebj.2019.33.1_supplement.666.5
Autor:
Isaac J. Dripps, Qin Wang, Emily M. Jutkiewicz, Kenner C. Rice, John R. Traynor, Richard R. Neubig
Publikováno v:
Psychopharmacology. 234:29-39
Regulator of G protein signaling (RGS) proteins act as negative modulators of G protein signaling. RGS4 has been shown to negatively modulate G protein signaling mediated by the delta opioid receptor (DOPr) in vitro. However, the role of RGS4 in modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3a4d9b367381f3b28ee0c7aaf27304
https://doi.org/10.1007/s00213-016-4432-5
https://doi.org/10.1007/s00213-016-4432-5
Autor:
Isaac J, Dripps, Emily M, Jutkiewicz
Publikováno v:
Handbook of experimental pharmacology. 247
Depression is a pervasive and debilitating mental disorder that is inadequately treated by current pharmacotherapies in a majority of patients. Although opioids have long been known to regulate mood states, the use of opioids to treat depression is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2142cd74f31d24f745cf078b2946bc6
https://pubmed.ncbi.nlm.nih.gov/28993835
https://pubmed.ncbi.nlm.nih.gov/28993835
Autor:
Isaac J, Dripps, Brett T, Boyer, Richard R, Neubig, Kenner C, Rice, John R, Traynor, Emily M, Jutkiewicz
Publikováno v:
British journal of pharmacology. 175(6)
BACKGROUND AND PURPOSE: GPCRs exist in multiple conformations that can engage distinct signalling mechanisms which in turn may lead to diverse behavioural outputs. In rodent models, activation of the δ opioid receptor (δ‐receptor) has been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1e4b535a020fbd1864eac92dd4baec9
https://pubmed.ncbi.nlm.nih.gov/29278419
https://pubmed.ncbi.nlm.nih.gov/29278419
Autor:
Isaac J. Dripps, Emily M. Jutkiewicz
Publikováno v:
Delta Opioid Receptor Pharmacology and Therapeutic Applications ISBN: 9783319951317
Depression is a pervasive and debilitating mental disorder that is inadequately treated by current pharmacotherapies in a majority of patients. Although opioids have long been known to regulate mood states, the use of opioids to treat depression is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f6316c4ae79f1427b18062ec9dfafd8
https://doi.org/10.1007/164_2017_42
https://doi.org/10.1007/164_2017_42
