Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Isaac Goncalves"'
Autor:
David J. Kuter, Merlin Efraim, Jiri Mayer, Marek Trněný, Vickie McDonald, Robert Bird, Thomas Regenbogen, Mamta Garg, Zane Kaplan, Nikolay Tzvetkov, Philip Y. Choi, A.J. Gerard Jansen, Milan Kostal, Ross Baker, Jaromir Gumulec, Eun-Ju Lee, Ilona Cunningham, Isaac Goncalves, Margaret Warner, Ralph Boccia, Terry Gernsheimer, Waleed Ghanima, Olga Bandman, Regan Burns, Ann Neale, Dolca Thomas, Puneet Arora, Beiyao Zheng, Nichola Cooper
Publikováno v:
New England Journal of Medicine, 386(15), 1421-1431. Massachussetts Medical Society
BACKGROUND Rilzabrutinib, an oral, reversible covalent inhibitor of Bruton's tyrosine kinase, may increase platelet counts in patients with immune thrombocytopenia by means of dual mechanisms of action: decreased macrophage (Fcγ receptor)-mediated p
Autor:
Anoop K Enjeti, Robert Bird, Isaac Goncalves, Chee Wee Tan, Philip Yi Choi, Ashwini Bennett, Danny Hsu, Eileen Merriman
Publikováno v:
Medical Journal of Australia. 216:43-52
Introduction The absence of high quality evidence for basic clinical dilemmas in immune thrombocytopenic purpura (ITP) underlines the need for contemporary guidelines relevant to the local treatment context. ITP is diagnosed by exclusions, with a hal
Autor:
Saffanah Zahra, Paul S. Myles, Isaac Goncalves, Gryselda Hanafi, Huyen Tran, Anton Ilich, Heidi Ho, Charithani B. Keragala, Nigel S. Key, Dominik F. Draxler, Robert L. Medcalf
Publikováno v:
Blood Coagulation & Fibrinolysis. 32:172-179
Tranexamic acid (TXA) is a lysine analogue that inhibits plasmin generation and has been used for decades as an antifibrinolytic agent to reduce bleeding. Recent reports have indicated that TXA can paradoxically promote plasmin generation. Blood was
Autor:
Piers Blombery, Michael S Hofman, Grace Kong, Michael Michael, Tim Akhurst, Kate Burbury, Rodney J. Hicks, David Westerman, Ing S. Tiong, Isaac Goncalves, Aravind S. Ravi Kumar, Amir Iravani
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 46:1902-1910
Peptide receptor radionuclide/chemoradionuclide therapy (PRRT/PRCRT) is an effective therapy for metastatic neuroendocrine neoplasia (NEN), but therapy-related myeloid neoplasms (t-MN) remain of concern. The study reviewed the clinicopathological fea
Autor:
Isaac Gonçalves da Silva, Lucimere Maria dos Santos, Raquel de Souza Ramos, Daniela Ferreira da Silva, Leonardo Andrade Ferreira de Carvalho, Denise Gonçalves Pereira de Oliveira, Raysa Rangel Marques
Publikováno v:
Revista Enfermagem Atual in Derme, Vol 98, Iss 3 (2024)
O objetivo do presente estudo é descrever a elaboração de um guia de orientação para o cuidado domiciliar de feridas tumorais, à luz dos pressupostos do letramento em saúde. Trata-se de um estudo metodológico que desenvolveu uma tecnologia ed
Externí odkaz:
https://doaj.org/article/22dd97719f734a97a2ce05852ea617b1
Autor:
Gryselda Hanafi, Dominik F. Draxler, Kah Yep, Isaac Goncalves, Anoushka Winton, Sophie Wallace, Paul S. Myles, Andrew Forbes, Robert L. Medcalf, Lisa M. Wutzlhofer, Heidi Ho, Maria Daglas, Huyen Tran, Magdalena Plebanski, Maithili Sashindranath
Publikováno v:
Blood advances. 3(10)
Tranexamic acid (TXA) is an antifibrinolytic agent that blocks plasmin formation. Because plasmin is known to promote inflammatory and immunosuppressive responses, we explored the possibility that plasmin-mediated immunosuppression in patients underg
Autor:
Michael S Hofman, Michael Michael, Amir Iravani, Ing S. Tiong, Grace Kong, Kate Burbury, Tim Akhurst, Piers Blombery, Aravind S. Ravi Kumar, Isaac Goncalves, David Westerman, Rodney J. Hicks
Publikováno v:
SSRN Electronic Journal.
Background: Peptide receptor radionuclide/chemoradionuclide therapy(PRRT/PRCRT) is an emerging therapy in patients with metastatic neuroendocrine neoplasia (NEN). However, therapy-related myeloid neoplasms (t-MN) remain a potential complication with
Autor:
Constantine S. Tam, Chloe Pek Sang Tang, Jenny Y. Y. Ooi, Isaac Goncalves, Andre La Gerche, Julie R. McMullen, Sasanka M. Handunnetti, Erin J. Howden
Publikováno v:
Blood. 134:4301-4301
The development of Bruton Kinase Inhibitors (BTKi) has been a major advance in the treatment of chronic lymphocytic leukaemia and related B cell malignancies, but atrial fibrillation (AF) and sudden cardiac deaths are emerging as unique side effects
Autor:
Denise Gonçalves Pereira de Oliveira, Lucimere Maria dos Santos, Isaac Gonçalves da Silva, Raphael Duarte Chança, Marcia Santos, Jorge Leandro do Souto Monteiro
Publikováno v:
Revista Enfermagem Atual in Derme, Vol 97, Iss 2 (2023)
Objetivo: Identificar nas publicações as orientações fornecidas pelo enfermeiro aos pacientes e cuidadores/familiares na alta hospitalar sobre o cuidado com a ferida neoplásica maligna. Metodologia: Trata-se de uma revisão integrativa sobre a p
Externí odkaz:
https://doaj.org/article/8a16d66f9cb348a2a6d2b1630b969e8c
Autor:
Shaun P. Jackson, Isaac Goncalves, Yuping Yuan, Simone M. Schoenwaelder, Cindy L. Yap, Sascha Claire Hughan
Publikováno v:
Journal of Biological Chemistry. 278:34812-34822
Platelet adhesion to fibrinogen is important for platelet aggregation and thrombus growth. In this study we have examined the mechanisms regulating platelet adhesion on immobilized fibrinogen under static and shear conditions. We demonstrate that int