Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Isaac Francos Quijorna"'
Publikováno v:
Frontiers in Aging, Vol 4 (2023)
Externí odkaz:
https://doaj.org/article/b68c135bc76245b69dd1c8522da2c394
Autor:
Isaac Francos-Quijorna, Marina Sánchez-Petidier, Emily R. Burnside, Smaranda R. Badea, Abel Torres-Espin, Lucy Marshall, Fred de Winter, Joost Verhaagen, Victoria Moreno-Manzano, Elizabeth J. Bradbury
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
Inflammation resolution failure is a pathological hallmark of spinal cord injury. Here, the authors show in rodents that chondroitin sulfate proteoglycans contribute to failed resolution by preventing immune cells at the injury core from converting t
Externí odkaz:
https://doaj.org/article/1fa069c153554f5aa4e6bb33426afeed
Autor:
Guillem Mòdol-Caballero, Mireia Herrando-Grabulosa, Sergi Verdés, Belén García-Lareu, Neus Hernández, Isaac Francos-Quijorna, Rubén López-Vales, Assumpció Bosch, Xavier Navarro
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting the neuromuscular system for which currently there is no effective therapy. Motoneuron (MN) degeneration involves several complex mechanisms, including surrounding gli
Externí odkaz:
https://doaj.org/article/de3aa861366a46a9a56f3e37e6182c97
Autor:
Joaquim Hernández, Isaac Francos-Quijorna, Elena Redondo-Castro, Rubén López-Vales, Xavier Navarro
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Research on microglia has established the differentiation between the so-called M1 and M2 phenotypes. However, new frameworks have been proposed attempting to discern between meaningful microglia profiles. We have set up an in vitro microglial activa
Externí odkaz:
https://doaj.org/article/851f5c06ec12437eb20d6330d918c1ee
Autor:
Guillem Mòdol-Caballero, Mireia Herrando-Grabulosa, Belén García-Lareu, Neus Solanes, Sergi Verdés, Rosario Osta, Isaac Francos-Quijorna, Rubèn López-Vales, Ana Cristina Calvo, Assumpció Bosch, Xavier Navarro
Publikováno v:
Neurobiology of Disease, Vol 137, Iss , Pp 104793- (2020)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder affecting motoneurons (MNs), with no effective treatment currently available. The molecular mechanisms that are involved in MN death are complex and not fully understood, with partia
Externí odkaz:
https://doaj.org/article/b575c34266b74f7da9212ad1f511120c
Autor:
Magdalene Joseph, Yin Wu, Richard Dannebaum, Florian Rubelt, Iva Zlatareva, Anna Lorenc, Zhipei Gracie Du, Daniel Davies, Fernanda Kyle-Cezar, Abhishek Das, Sarah Gee, Jeffrey Seow, Carl Graham, Dilduz Telman, Clara Bermejo, Hai Lin, Hosseinali Asgharian, Adam G. Laing, Irene del Molino del Barrio, Leticia Monin, Miguel Muñoz-Ruiz, Duncan R. McKenzie, Thomas S. Hayday, Isaac Francos-Quijorna, Shraddha Kamdar, Richard Davis, Vasiliki Sofra, Florencia Cano, Efstathios Theodoridis, Lauren Martinez, Blair Merrick, Karen Bisnauthsing, Kate Brooks, Jonathan Edgeworth, John Cason, Christine Mant, Katie J. Doores, Pierre Vantourout, Khai Luong, Jan Berka, Adrian C. Hayday
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(34)
Whereas pathogen-specific T and B cells are a primary focus of interest during infectious disease, we have used COVID-19 to ask whether their emergence comes at a cost of broader B cell and T cell repertoire disruption. We applied a genomic DNA-based
Autor:
Jennifer Vidler, Shubhankar Sinha, Helen Kakkassery, Jack Cooper, Thanussuyah Alaguthurai, Thomas Hayday, Ana Montes, Yin Wu, Puay Ling Lee, Shraddha Kamdar, Leticia Monin, Muhammad Shamim Khan, Rosalind Graham, Daniel Davies, Maria Conde Poole, Miguel Muñoz-Ruiz, Adam Laing, Charlotte O'Brien-Gore, Sheeba Irshad, Sophie Papa, Anne Rigg, Elizabeth Harvey-Jones, Piers E.M. Patten, Magdalene Joseph, Paul Fields, Clara Domingo-Vila, Mark Harries, Francesca Di Rosa, Jeffrey Seow, Richard Davis, Adrian Hayday, Katie J. Doores, Duncan R. McKenzie, Isaac Francos Quijorna, Josephine Eum, Angela Swampillai, Timothy Tree, Bernard V. North, Liane Dupont, James Spicer, Michael H. Malim, Sultan Abdul-Jawad, Carl Graham, Irene del Molino del Barrio
Publikováno v:
Lancet oncology
22 (2021): 765–778. doi:10.1016/S1470-2045(21)00213-8
info:cnr-pdr/source/autori:Monin, Leticia; Laing, Adam G.; Muñoz-Ruiz, Miguel; McKenzie, Duncan R.; del Molino del Barrio, Irene; Alaguthurai, Thanussuyah; Domingo-Vila, Clara; Hayday, Thomas S.; Graham, Carl; Seow, Jeffrey; Abdul-Jawad, Sultan; Kamdar, Shraddha; Harvey-Jones, Elizabeth; Graham, Rosalind; Cooper, Jack; Khan, Muhammad; Vidler, Jennifer; Kakkassery, Helen; Sinha, Shubhankar; Davis, Richard; Dupont, Liane; Francos Quijorna, Isaac; O'Brien-Gore, Charlotte; Lee, Puay Ling; Eum, Josephine; Conde Poole, Maria; Joseph, Magdalene; Davies, Daniel; Wu, Yin; Swampillai, Angela; North, Bernard V.; Montes, Ana; Harries, Mark; Rigg, Anne; Spicer, James; Malim, Michael H.; Fields, Paul; Patten, Piers; Di Rosa, Francesca; Papa, Sophie; Tree, Timothy; Doores, Katie J.; Hayday, Adrian C.; Irshad, Sheeba/titolo:Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study/doi:10.1016%2FS1470-2045(21)00213-8/rivista:Lancet oncology (Print)/anno:2021/pagina_da:765/pagina_a:778/intervallo_pagine:765–778/volume:22
The Lancet. Oncology
22 (2021): 765–778. doi:10.1016/S1470-2045(21)00213-8
info:cnr-pdr/source/autori:Monin, Leticia; Laing, Adam G.; Muñoz-Ruiz, Miguel; McKenzie, Duncan R.; del Molino del Barrio, Irene; Alaguthurai, Thanussuyah; Domingo-Vila, Clara; Hayday, Thomas S.; Graham, Carl; Seow, Jeffrey; Abdul-Jawad, Sultan; Kamdar, Shraddha; Harvey-Jones, Elizabeth; Graham, Rosalind; Cooper, Jack; Khan, Muhammad; Vidler, Jennifer; Kakkassery, Helen; Sinha, Shubhankar; Davis, Richard; Dupont, Liane; Francos Quijorna, Isaac; O'Brien-Gore, Charlotte; Lee, Puay Ling; Eum, Josephine; Conde Poole, Maria; Joseph, Magdalene; Davies, Daniel; Wu, Yin; Swampillai, Angela; North, Bernard V.; Montes, Ana; Harries, Mark; Rigg, Anne; Spicer, James; Malim, Michael H.; Fields, Paul; Patten, Piers; Di Rosa, Francesca; Papa, Sophie; Tree, Timothy; Doores, Katie J.; Hayday, Adrian C.; Irshad, Sheeba/titolo:Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study/doi:10.1016%2FS1470-2045(21)00213-8/rivista:Lancet oncology (Print)/anno:2021/pagina_da:765/pagina_a:778/intervallo_pagine:765–778/volume:22
The Lancet. Oncology
Summary Background The efficacy and safety profiles of vaccines against SARS-CoV-2 in patients with cancer is unknown. We aimed to assess the safety and immunogenicity of the BNT162b2 (Pfizer–BioNTech) vaccine in patients with cancer. Methods For t
Autor:
Maria Puigdomenech, Rubèn López-Vales, Isaac Francos-Quijorna, Joana Garcia-Garcia, Damaris B. Skouras, Jesus Amo-Aparicio, Charles A. Dinarello
Publikováno v:
Experimental Neurology, 347
Spinal cord injury (SCI) leads to irreversible functional deficits due to the disruption of axons and the death of neurons and glial cells. The inflammatory response that occurs in the injured spinal cord results in tissue degeneration; thus, targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d86c76c965a476bd15ecf6e991242980
https://repository.ubn.ru.nl/handle/2066/239955
https://repository.ubn.ru.nl/handle/2066/239955
Autor:
Xavier Navarro, Elena Redondo-Castro, Isaac Francos-Quijorna, Rubèn López-Vales, Joaquim Hernández
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Research on microglia has established the differentiation between the so-called M1 and M2 phenotypes. However, new frameworks have been proposed attempting to discern between meaningful microglia profiles. We have set up an in vitro microglial activa
Autor:
Eva Santos-Nogueira, Rubèn López-Vales, Jerold Chun, Isaac Francos-Quijorna, Marina Coll-Miró, Clara López-Serrano
Publikováno v:
Brain, Behavior, and Immunity. 76:258-267
Lysophosphatidic acid (LPA) is an extracellular lipid mediator involved in many physiological functions by signaling through six known G-protein-coupled receptors (LPA(1)-LPA(6)). In the central nervous system (CNS), LPA mediates a wide range of effe