Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Isaac E. Erickson"'
Autor:
Robert L. Mauck, Alice H. Huang, Isaac E. Erickson, Minwook Kim, Sean T. Garrity, David R. Steinberg
Publikováno v:
Tissue Engineering Part A. 24:1693-1703
Mesenchymal stem cells (MSCs) are an attractive cell type for cartilage repair that can undergo chondrogenesis in a variety of three-dimensional (3D) scaffolds. Hyaluronic acid (HA) hydrogels provide a biologically relevant interface for cell encapsu
Autor:
Subba R. Chintalacharuvu, Isaac E. Erickson, Antwain Howard, Galina Dulatova, Beverly Lundell, Kevin T. Foley, Terry Tandeski, Tricia Wolff, Lara Silverman, David Toplon
Publikováno v:
The spine journal : official journal of the North American Spine Society. 20(1)
BACKGROUND/CONTEXT Disc degeneration (DD) is a significant driver of low back pain and few treatments exist to treat the pain and disability associated with the disease. PURPOSE Our group has developed a method to generate therapeutic discogenic cell
Publikováno v:
Clinical Orthopaedics & Related Research. 469:2744-2753
Cartilage degeneration is common in the aged, and aged chondrocytes are inferior to juvenile chondrocytes in producing cartilage-specific extracellular matrix. Mesenchymal stem cells (MSCs) are an alternative cell type that can differentiate toward t
Autor:
Isaac E. Erickson, Sydney R. Kestle, Jason A. Burdick, Swarnali Sengupta, Alice H. Huang, Robert L. Mauck
Publikováno v:
Osteoarthritis and Cartilage. 17:1639-1648
Summary Objective Engineering cartilage requires that a clinically relevant cell type be situated within a 3D environment that supports cell viability, the production and retention of cartilage-specific extracellular matrix (ECM), and eventually, the
Autor:
Ryan T. Li, Robert L. Mauck, Cindy Chung, Jason A. Burdick, Isaac E. Erickson, Alice H. Huang
Publikováno v:
Tissue Engineering Part A. 15:1041-1052
Degenerative disease and damage to articular cartilage represents a growing concern in the aging population. New strategies for engineering cartilage have employed mesenchymal stem cells (MSCs) as a cell source. However, recent work has suggested tha
Publikováno v:
Tissue Engineering Part A. 14:1121-1131
Chondrocytes isolated from a variety of sources, including auricular (AU) and articular (AR) cartilage, can differ in cell behavior, growth, and extracellular matrix (ECM) production, which can impact neocartilage properties in tissue engineering app
Autor:
Minwook Kim, Isaac E. Erickson, Kilief H. Zellars, Robert L. Mauck, Megan J. Farrell, Sydney R. Kestle, Jason A. Burdick
Engineered cartilage based on adult mesenchymal stem cells (MSCs) is an alluring goal for the repair of articular defects. However, efforts to date have failed to generate constructs with sufficient mechanical properties to function in the demanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf77b092ce35c4acbfbb506106778c1
https://europepmc.org/articles/PMC3389207/
https://europepmc.org/articles/PMC3389207/
Autor:
Jason A. Burdick, Alice H. Huang, Minwook Kim, Robert L. Mauck, Isaac E. Erickson, Sean T. Garrity
Publikováno v:
2012 38th Annual Northeast Bioengineering Conference (NEBEC).
Mesenchymal stem cells are attractive cell type and can undergo chondrogenesis in various 3D platforms. Hyaluronic acid (HA) hydrogel, a natural constituent of the cartilage extracellular matrix, provides a biologically relevant interface for encapsu
Publikováno v:
Journal of the mechanical behavior of biomedical materials. 11
Tissue engineering with adult stem cells is a promising approach for the restoration of focal defects in articular cartilage. For this, progenitor cells would ideally be delivered to (and maintained within) the defect site via a biocompatible materia
Publikováno v:
ASME 2011 Summer Bioengineering Conference, Parts A and B.
Articular cartilage is the primary compressive load bearing soft tissue in diarthrodial joints. While the tissue can function remarkably well in a demanding environment over a lifetime of use, focal defects and other trauma can initiate progressive d