Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Isaac E García"'
Autor:
Mauricio Antonio Retamal, Isaac E García, Bernardo ePinto, Amaury ePupo, David eBaez-Nieto, Jimmy eStehberg, RODRIGO eDEL RIO, Carlos eGonzalez
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Connexin-based channels comprise hemichannels and gap junction channels. The opening of hemichannels allow for the flux of ions and molecules from the extracellular space into the cell and vice versa. Similarly, the opening of gap junction channels p
Externí odkaz:
https://doaj.org/article/e885203f7c34465cbaf9e8b87e90558e
Autor:
Felipe Villanelo, Peter J. Minogue, Jaime Maripillán, Mauricio Reyna-Jeldes, Joaquin Jensen-Flores, Isaac E. García, Eric C. Beyer, Tomás Pérez-Acle, Viviana M. Berthoud, Agustín D. Martínez
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-18 (2024)
Abstract Background Members of the β-subfamily of connexins contain an intracellular pocket surrounded by amino acid residues from the four transmembrane helices. The presence of this pocket has not previously been investigated in members of the α-
Externí odkaz:
https://doaj.org/article/06defa631d704d8c9d7c419ba703475f
Autor:
Oscar Jara, Jaime Maripillán, Fanny Momboisse, Ana María Cárdenas, Isaac E. García, Agustín D. Martínez
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7246 (2024)
Connexins (Cxs) are transmembrane proteins that assemble into gap junction channels (GJCs) and hemichannels (HCs). Previous researches support the involvement of Rho GTPases and actin microfilaments in the trafficking of Cxs, formation of GJCs plaque
Externí odkaz:
https://doaj.org/article/9ba926a964484e14aa81a6579f880d2e
Autor:
Ana C. Abbott, Isaac E. García, Felipe Villanelo, Carolina Flores-Muñoz, Ricardo Ceriani, Jaime Maripillán, Joel Novoa-Molina, Cindel Figueroa-Cares, Tomas Pérez-Acle, Juan C. Sáez, Helmuth A. Sánchez, Agustín D. Martínez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Some mutations in gap junction protein Connexin 26 (Cx26) lead to syndromic deafness, where hearing impairment is associated with skin disease, like in Keratitis Ichthyosis Deafness (KID) syndrome. This condition has been linked to hyperactivity of c
Externí odkaz:
https://doaj.org/article/4a2519a57af545099c4f91f689d29670
Autor:
Wilfredo Alejandro González-Arriagada, Isaac E. García, René Martínez-Flores, Sebastián Morales-Pison, Ricardo D. Coletta
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 478 (2022)
The interaction between malignant cells and the tumor microenvironment is critical for tumor progression, and the chemokine ligand/receptor axes play a crucial role in this process. The CXCR4/CXCL12 and CCR5/CCL5 axes, both related to HIV, have been
Externí odkaz:
https://doaj.org/article/e753dbcc7f3643ef9b8d0f9f7b38b8a3
Autor:
Angelina Palacios-Muñoz, Danielle de Paula Moreira, Valeria Silva, Isaac E. García, Francisco Aboitiz, Mehdi Zarrei, Gabriele Campos, Olivia Rennie, Jennifer L. Howe, Evdokia Anagnostou, Patricia Ambrozewic, Stephen W. Scherer, Maria Rita Passos-Bueno, John Ewer
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Autism Spectrum Disorder (ASD) is characterized by impaired social communication, restricted interests, and repetitive and stereotyped behaviors. The TRPC6 (transient receptor potential channel 6) represents an ASD candidate gene under an oligogenic/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73218a21d32fcb32fa3e40746823b2e8
https://doi.org/10.1038/s41380-022-01555-1
https://doi.org/10.1038/s41380-022-01555-1
Autor:
Carolina Flores-Muñoz, Jaime Maripillán, Jacqueline Vásquez-Navarrete, Joel Novoa-Molina, Ricardo Ceriani, Helmuth A. Sánchez, Ana C. Abbott, Caroline Weinstein-Oppenheimer, Donald I. Brown, Ana María Cárdenas, Isaac E. García, Agustín D. Martínez
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1069 (2021)
Wound healing is a dynamic process required to maintain skin integrity and which relies on the precise migration of different cell types. A key molecule that regulates this process is ATP. However, the mechanisms involved in extracellular ATP managem
Externí odkaz:
https://doaj.org/article/147cbf8208f44eea86a4905123c43b40
Autor:
Donald I. Brown, Jaime Maripillán, Carolina Flores-Muñoz, Joel Novoa-Molina, Ana C Abbott, Caroline Weinstein-Oppenheimer, Ricardo Ceriani, Jacqueline Vásquez-Navarrete, Isaac E. García, Ana M. Cárdenas, Agustín D. Martínez, Helmuth A. Sánchez
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 1069, p 1069 (2021)
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1069, p 1069 (2021)
Volume 22
Issue 3
Wound healing is a dynamic process required to maintain skin integrity and which relies on the precise migration of different cell types. A key molecule that regulates this process is ATP. However, the mechanisms involved in extracellular ATP managem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802e3569e5a1910e5a65363745b1b089
http://europepmc.org/articles/PMC7865282
http://europepmc.org/articles/PMC7865282
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1860:91-95
Connexins are membrane proteins that form hemichannels and gap junction channels at the plasma membrane. Through these channels connexins participate in autocrine and paracrine intercellular communication. Connexin-based channels are tightly regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746f67f5978e4824c044268576752f0f
https://doi.org/10.1016/j.bbamem.2017.10.006
https://doi.org/10.1016/j.bbamem.2017.10.006
Autor:
Kenya D. Romero-Castillo, Lizeth Parra-Arroyo, Hafiz M.N. Iqbal, Juan Eduardo Sosa-Hernández, Muhammad Bilal, Ishtiaq Ahmed, Roberto Parra-Saldívar, Isaac E. García-Reyes, Mauricio A. Aguilar-Aguila-Isaías
Publikováno v:
Marine Drugs
In recent years, the demand for naturally derived products has hiked with enormous pressure to propose or develop state-of-the-art strategies to meet sustainable circular economy challenges. Microalgae possess the flexibility to produce a variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631b0b69e30c853cba55b5c8ca4cd604
https://pubmed.ncbi.nlm.nih.gov/30889823
https://pubmed.ncbi.nlm.nih.gov/30889823