Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Isaac E, Stillman"'
Autor:
Insa M. Schmidt, Aditya L. Surapaneni, Runqi Zhao, Dhairya Upadhyay, Wan-Jin Yeo, Pascal Schlosser, Courtney Huynh, Anand Srivastava, Ragnar Palsson, Taesoo Kim, Isaac E. Stillman, Daria Barwinska, Jonathan Barasch, Michael T. Eadon, Tarek M. El-Achkar, Joel Henderson, Dennis G. Moledina, Sylvia E. Rosas, Sophie E. Claudel, Ashish Verma, Yumeng Wen, Maja Lindenmayer, Tobias B. Huber, Samir V. Parikh, John P. Shapiro, Brad H. Rovin, Ian B. Stanaway, Neha A. Sathe, Pavan K. Bhatraju, Josef Coresh, the Kidney Precision Medicine Project, Eugene P. Rhee, Morgan E. Grams, Sushrut S. Waikar
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The kidney tubules constitute two-thirds of the cells of the kidney and account for the majority of the organ’s metabolic energy expenditure. Acute tubular injury (ATI) is observed across various types of kidney diseases and may significan
Externí odkaz:
https://doaj.org/article/41855c04b12d4c92a5497040b3021033
Autor:
Carolina Lopez-Silva, Aditya Surapaneni, Insa M. Schmidt, Dhairya Upadhyay, Anand Srivastava, Ragnar Palsson, Isaac E. Stillman, Eugene P. Rhee, Sushrut S. Waikar, Morgan E. Grams
Publikováno v:
Kidney Medicine, Vol 6, Iss 12, Pp 100920- (2024)
Rationale & Objective: Diabetic kidney disease (DKD) is one of the leading causes of end-stage kidney disease globally. We aim to identify proteomic and metabolomic correlates of histologically confirmed DKD that may improve our understanding of its
Externí odkaz:
https://doaj.org/article/edc82158c78f4bb296a073fbf61957d9
Autor:
Hao Li, Iannis E. Adamopoulos, Vaishali R. Moulton, Isaac E. Stillman, Zach Herbert, James J. Moon, Amir Sharabi, Suzanne Krishfield, Maria G. Tsokos, George C. Tsokos
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Splenic marginal zone macrophages can establish immune tolerance and limit the development of systemic lupus erythematosus (SLE). Here the authors show that these cells do this by clearing apoptotic cells, and defects in these cells result in the gen
Externí odkaz:
https://doaj.org/article/e6b55468c2854d60ac861be67cb25f57
Autor:
Ragnar Palsson, Samuel A.P. Short, Zoe A. Kibbelaar, Afolarin Amodu, Isaac E. Stillman, Helmut G. Rennke, Gearoid M. McMahon, Sushrut S. Waikar
Publikováno v:
Kidney International Reports, Vol 5, Iss 4, Pp 511-518 (2020)
Background: The major risk of kidney biopsy is severe bleeding. Numerous risk factors for bleeding after biopsy have been reported, but findings have been inconsistent. Methods: We retrospectively reviewed medical records of adult patients enrolled i
Externí odkaz:
https://doaj.org/article/30bb5a40903e4fcf9f9d6bca82f0956e
Autor:
Gizelle M. McCarthy, Angelo Blasio, Olivia G. Donovan, Lena B. Schaller, Althea Bock-Hughes, Jose M. Magraner, Jung Hee Suh, Calum F. Tattersfield, Isaac E. Stillman, Shrijal S. Shah, Zsuzsanna K. Zsengeller, Balajikarthick Subramanian, David J. Friedman, Martin R. Pollak
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 8 (2021)
People of recent sub-Saharan African ancestry develop kidney failure much more frequently than other groups. A large fraction of this disparity is due to two coding sequence variants in the APOL1 gene. Inheriting two copies of these APOL1 risk varian
Externí odkaz:
https://doaj.org/article/a287463f226b4e8fbb37835daa607c31
Autor:
Rhea Bhargava, Sylvain Lehoux, Kayaho Maeda, Maria G. Tsokos, Suzanne Krishfield, Lena Ellezian, Martin Pollak, Isaac E. Stillman, Richard D. Cummings, George C. Tsokos
Publikováno v:
JCI Insight, Vol 6, Iss 9 (2021)
Lupus nephritis (LN) is a serious complication occurring in 50% of patients with systemic lupus erythematosus (SLE) for which there is a lack of biomarkers, a lack of specific medications, and a lack of a clear understanding of its pathogenesis. The
Externí odkaz:
https://doaj.org/article/9d9f44188c2d4830bb1e524b3bc42211
Autor:
Ali Poyan Mehr, Maryam Sadeghi-Najafabadi, Kristi Chau, Joseph Messmer, Rima Pai, Neil Roy, David Friedman, Martin R. Pollak, Johannes Schlondorff, Mihran Naljayan, Tripti Singh, Stewart H. Lecker, Roger Rodby, Michael Germain, Helmut Rennke, Isaac E. Stillman
Publikováno v:
Kidney International Reports, Vol 4, Iss 1, Pp 20-29 (2019)
Glomerular kidney disorders account for a significant proportion of chronic kidney disease and end-stage renal disease worldwide. Nevertheless, major obstacles make breakthrough progress in diagnosis and cure an ongoing challenge. Here we report the
Externí odkaz:
https://doaj.org/article/e12b0fcdabab47a6b630f384c2e71b50
Autor:
Insa M Schmidt, Steele Myrick, Jing Liu, Ashish Verma, Anand Srivastava, Ragnar Palsson, Ingrid F Onul, Isaac E Stillman, Claire Avillach, Prasad Patil, Sushrut S Waikar
Publikováno v:
Clinical Kidney Journal. 16:90-99
Background Protein biomarkers may provide insight into kidney disease pathology but their use for the identification of phenotypically distinct kidney diseases has not been evaluated. Methods We used unsupervised hierarchical clustering on 225 plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ea03898556e3102c5db00bbd0f24263
https://doi.org/10.1093/ckj/sfac202
https://doi.org/10.1093/ckj/sfac202
Autor:
Timothy Maher, Robert D’Angelo, Nicholas Palmeri, Ibidunni Bode-Sojobi, Paul VanderLaan, Jeffrey Larnard, Isaac E. Stillman, Peter Zimetbaum
Publikováno v:
JACC: Clinical Electrophysiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::481d923252d6b5091ef4d1df968ad160
https://doi.org/10.1016/j.jacep.2023.03.011
https://doi.org/10.1016/j.jacep.2023.03.011
Autor:
Adolf W. Karchmer, John M. Giurini, Vimal V Jhaveri, Jason A. Freed, Isaac E. Stillman, Wendy Stead, Ashley Ward, Mary T. LaSalvia, Roger B. Davis, Christopher Sullivan
Publikováno v:
Journal of the American Podiatric Medical Association. 112
Background: Diabetic foot osteomyelitis is a common infection where treatment involves multiple services, including infectious diseases, podiatry, and pathology. Despite its ubiquity in the hospital, consensus on much of its management is lacking. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12135de5b50f14adeaa0aecce3843cc5
https://doi.org/10.7547/20-178
https://doi.org/10.7547/20-178