Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Isaac Djerassi"'
Autor:
Jung Sun Kim, Isaac Djerassi
Publikováno v:
Cancer. 38:1043-1051
High doses of methotrexate (HDMTX), given in pulse infusions of 3 to 30 mg/kg body weight, were studied in 22 children with non-Hodgkin's lymphoma. Sixteen complete and five partial remissions were observed in 21 patients evaluable for remission indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbd3cfe453ddda16099ca7f04d08b30e
https://doi.org/10.1002/1097-0142(197609)38:3<1043::aid-cncr2820380302>3.0.co
https://doi.org/10.1002/1097-0142(197609)38:3<1043::aid-cncr2820380302>3.0.co
Publikováno v:
Blood. 44:707-713
Preparation of granulocytes for transfusion in high yield and relatively free of contamination by other cell types has been made possible by the technique of continuous-flow filtration leukapheresis (CFFL). Since previous work suggested that granuloc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1d1766b896425b8c1ea21349c216aa5
https://doi.org/10.1182/blood.v44.5.707.707
https://doi.org/10.1182/blood.v44.5.707.707
Autor:
Robert W. Case, Dutzu Rosner, Ole A. Holtermann, Edmund Klein, Halina Milgrom, Isaac Djerassi, Doug Klein
Publikováno v:
Medical Clinics of North America. 60:389-418
Courses of repeated delayed hypersensitivity challenge reactions at the sites of tumors have been shown to eradicate malignant and premalignant epidermal neoplasms. Local immunotherapy produces therapeutic responses in malignant and premalignant lesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054ee9f4d2602bff146f1c886a2e55bb
https://doi.org/10.1016/s0025-7125(16)31888-0
https://doi.org/10.1016/s0025-7125(16)31888-0
Autor:
Faye C. Austin, Edmund Klein, Isaac Djerassi, John A. Cavins, David L. Levin, Robert W. Case, Dutzu Rosner, Charles W. Boone
Publikováno v:
Cancer. 49:2034-2042
Crude membrane (CM) extracts were prepared from five cultured breast tumor lines (MDA-MB-157, MDA-MB-231, ZR75-1, HS0578T, and MCF-7) which had been infected with vesicular stomatitis virus (VSV) to augment their antigenicity. In skin test trials, CM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::964cb44433945736236f9b5a51097303
https://doi.org/10.1002/1097-0142(19820515)49:10<2034::aid-cncr2820491016>3.0.co
https://doi.org/10.1002/1097-0142(19820515)49:10<2034::aid-cncr2820491016>3.0.co
Autor:
Avner Reggev, Isaac Djerassi
Publikováno v:
Cancer. 61:2423-2428
A total of 45 courses of 50 g (24 to 33 g/m2) of high-dose methotrexate (HDMTX) followed by an improved citrovorum rescue (CFR) were administered to 23 patients according to a recently updated procedure. All patients previously had received HDMTX-CFR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eaa666d371ab5186aae41cffba22673
https://doi.org/10.1002/1097-0142(19880615)61:12<2423::aid-cncr2820611205>3.0.co
https://doi.org/10.1002/1097-0142(19880615)61:12<2423::aid-cncr2820611205>3.0.co
Publikováno v:
Cancer. 55:2741-2747
Eleven patients with astrocytoma were treated with high-dose methotrexate (HDMTX) and citrovorum factor rescue (CFR). Clinical response was observed in eight patients, including four of four with grade 3 disease, one of one with grade 2 to 3, two of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2988b4feea7e90805e46991cafacd32b
https://doi.org/10.1002/1097-0142(19850615)55:12<2741::aid-cncr2820551202>3.0.co
https://doi.org/10.1002/1097-0142(19850615)55:12<2741::aid-cncr2820551202>3.0.co
Publikováno v:
Cryobiology. 5:60-69
Summary The low temperature preservation of leukocytes has been emphasized recently owing to its inherent application in the treatment of leukopenic individuals. Ten per cent dimethyl sulfoxide has evolved as the additive of choice for this cell syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea884d9b833f5bd931b268a64e9fdf9a
https://doi.org/10.1016/s0011-2240(68)80145-2
https://doi.org/10.1016/s0011-2240(68)80145-2
Autor:
Isaac Djerassi, Albert J. Roy
Publikováno v:
Blood. 22:703-717
Rat platelets were frozen in liquid nitrogen (-195 C.) without losing their morphologic integrity and their ability to circulate in thrombocytopenic recipient animals. The simultaneous presence of two preservative agents—a sugar and dimethylsulfoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b1377509f1e02a4c7f43f1555b979a0
https://doi.org/10.1182/blood.v22.6.703.703
https://doi.org/10.1182/blood.v22.6.703.703
Publikováno v:
Experimental Biology and Medicine. 111:15-18
Fresh human platelets transfused into irradiated thrombocytopenic rats are removed from the circulation within 2 to 3 hours. The output of red blood cells into the lymph is reduced (--70%) despite the declining platelet count. The effects of fresh ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb768813c1b4b2cd4912a4bc0dbbe18
https://doi.org/10.3181/00379727-111-27692
https://doi.org/10.3181/00379727-111-27692
Autor:
Isaac Djerassi, Albert J. Roy
Publikováno v:
Circulation Research. 10:758-762
The lymph collected from the left thoracic lymph duct of dogs in severe shock due to blood loss becomes grossly hemorrhagic. Reversible hemorrhagic shock is not accompanied by changes in lymph appearance or content of red blood cells. The increased l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6140c7b4f7eb59853d1541625b4d07
https://doi.org/10.1161/01.res.10.5.758
https://doi.org/10.1161/01.res.10.5.758