Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Isaac D. Gukas"'
Autor:
Isaac D. Gukas, Anne C. Girling, Barnabas M. Mandong, Wendy Prime, Barbara A. Jennings, Samuel J. Leinster
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 2 (2008)
Background Some studies have suggested that breast cancer in black women is more aggressive than in white women. This study's aim was to look for evidence of differences in tumour biology between the two cohorts. Methods This study compared the stage
Externí odkaz:
https://doaj.org/article/46613892936a4731b2a6014209c6b68e
Autor:
Michael W. Retsky, Rick A. Rogers, William J. M. Hrushesky, Marc DeKock, Patrice Forget, Michael Baum, Katharina Pachmann, Isaac D. Gukas, Jayant S. Vaidya, Romano Demicheli
Publikováno v:
Breast Cancer Research and Treatment. 134:881-888
To explain a bimodal relapse hazard among early stage breast cancer patients treated by mastectomy we postulated that relapses within 4 years of surgery resulted from something that happened at about the time of surgery to provoke sudden exits from d
Publikováno v:
Cancers, Vol 2, Iss 2, Pp 305-337 (2010)
Cancers
Cancers
We review our work over the past 14 years that began when we were first confronted with bimodal relapse patterns in two breast cancer databases from different countries. These data were unexplainable with the accepted continuous tumor growth paradigm
Publikováno v:
Medical Teacher. 32:e5-e11
During problem-based learning (PBL), students brainstorm on a problem, generate hypotheses and formulate learning objectives. Certain verbal and non-verbal expressions are used by students in response to specific learning issues.This study examines t
Publikováno v:
Annals of Oncology. 19:1821-1828
A few clinical investigations suggest that while primary breast cancer surgical removal favorably modifies the natural history for some patients, it may also hasten the metastatic development for others. The concepts underlying this disease paradigm,
Publikováno v:
APMIS. 116:730-741
To explain bimodal relapse patterns observed in breast cancer data, we have proposed that metastatic breast cancer growth commonly includes periods of temporary dormancy at both the single cell phase and the avascular micrometastasis phase. The half-
Publikováno v:
Breast Cancer Online. 10:1-6
To explain bimodal relapse patterns, we have previously suggested that metastatic breast cancer growth commonly includes periods of temporary dormancy at both the single cell and avascular micrometastasis phases (with 1 year and 2 year half-lives res
Autor:
Isaac D. Gukas
Publikováno v:
Medical Teacher. 29:887-892
Introduction: When medical education became established in Africa, many curricula were adopted from the West so as to achieve comparable standards in training. Over the last half a century however, major global pedagogical shifts have occurred in med
Autor:
Isaac D. Gukas, N. Mbah
Publikováno v:
International Journal of Surgery. 3(2):117-119
We studied the terminal events preceding death in all patients dying in hospital over a period of 10 years. Hepatomegaly, massive ascites, cachexia, jaundice, massive pleural effusion and haemoptysis were the most frequent terminal events. The predom
Autor:
Isaac D. Gukas, Michael Baum, Marc De Kock, Jayant S. Vaidya, Patrice Forget, Michael W. Retsky, Rick A. Rogers, Romano Demicheli, William J. M. Hrushesky, Vikas P. Sukhatme
Publikováno v:
Current Medicinal Chemistry
To explain a bimodal pattern of hazard of relapse among early stage breast cancer patients identified in multiple databases, we proposed that late relapses result from steady stochastic progressions from single dormant malignant cells to avascular mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c9897a783dc1c75c31fd8bdf1536e6
http://arxiv.org/abs/1308.3690
http://arxiv.org/abs/1308.3690