Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Isaac B. Nelson"'
Autor:
Madison F Walker, Jingyi Zhang, William Steiner, Pei-I Ku, Ju-Fen Zhu, Zachary Michaelson, Yu-Chen Yen, Annabel Lee, Alyssa B Long, Mattie J Casey, Abhishek Poddar, Isaac B Nelson, Corvin D Arveseth, Falko Nagel, Ryan Clough, Sarah LaPotin, Kristen M Kwan, Stefan Schulz, Rodney A Stewart, John J G Tesmer, Tamara Caspary, Radhika Subramanian, Xuecai Ge, Benjamin R Myers
Publikováno v:
PLoS Biology, Vol 22, Iss 8, p e3002685 (2024)
During Hedgehog (Hh) signal transduction in development and disease, the atypical G protein-coupled receptor (GPCR) SMOOTHENED (SMO) communicates with GLI transcription factors by binding the protein kinase A catalytic subunit (PKA-C) and physically
Externí odkaz:
https://doaj.org/article/dd4df563bde8484e9cf388d6a8c3f333
Autor:
Corvin D Arveseth, John T Happ, Danielle S Hedeen, Ju-Fen Zhu, Jacob L Capener, Dana Klatt Shaw, Ishan Deshpande, Jiahao Liang, Jiewei Xu, Sara L Stubben, Isaac B Nelson, Madison F Walker, Kouki Kawakami, Asuka Inoue, Nevan J Krogan, David J Grunwald, Ruth Hüttenhain, Aashish Manglik, Benjamin R Myers
Publikováno v:
PLoS Biology, Vol 19, Iss 4, p e3001191 (2021)
The Hedgehog (Hh) pathway is essential for organ development, homeostasis, and regeneration. Dysfunction of this cascade drives several cancers. To control expression of pathway target genes, the G protein-coupled receptor (GPCR) Smoothened (SMO) act
Externí odkaz:
https://doaj.org/article/216a829c67014ffaad7616967d505e59
Autor:
Madison F. Walker, Jingyi Zhang, William Steiner, Pei-I Ku, Ju-Fen Zhu, Zachary Michaelson, Yu-Chen Yen, Alyssa B. Long, Mattie J. Casey, Abhishek Poddar, Isaac B. Nelson, Corvin D. Arveseth, Falko Nagel, Ryan Clough, Sarah LaPotin, Kristen M. Kwan, Stefan Schulz, Rodney A. Stewart, John J. G. Tesmer, Tamara Caspary, Radhika Subramanian, Xuecai Ge, Benjamin R. Myers
Publikováno v:
bioRxiv
During Hedgehog (Hh) signal transduction in development, homeostasis, and cancer, the atypical G protein-coupled receptor (GPCR) SMOOTHENED (SMO) communicates with GLI transcription factors by directly binding the PKA catalytic subunit (PKA-C) and ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f849ab21c1dc2a9f085f18f5c84fc5
https://doi.org/10.1101/2023.05.10.540226
https://doi.org/10.1101/2023.05.10.540226
Autor:
Benjamin R. Myers, Isaac B. Nelson
Publikováno v:
Hedgehog Signaling ISBN: 9781071617007
Much of our current understanding of Hedgehog signal transduction derives from studies involving intact cells and organisms. Here we describe the use of cell-free and reconstituted systems to study a key step in Hedgehog signal transduction: the acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5ff103ae3c89a2ee2e7610c0e50f4e7
https://doi.org/10.1007/978-1-0716-1701-4_14
https://doi.org/10.1007/978-1-0716-1701-4_14
Autor:
Isaac B, Nelson, Benjamin R, Myers
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2374
Much of our current understanding of Hedgehog signal transduction derives from studies involving intact cells and organisms. Here we describe the use of cell-free and reconstituted systems to study a key step in Hedgehog signal transduction: the acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69a34e700368a8d8c366e150e4c4f86a
https://pubmed.ncbi.nlm.nih.gov/34562251
https://pubmed.ncbi.nlm.nih.gov/34562251
Autor:
Corvin D. Arveseth, Jacob L. Capener, Cristina Olivieri, Ju-Fen Zhu, Gianluigi Veglia, Lily Vu, Jan Wilfried Bröckel, C.C. King, Danielle S. Hedeen, John T. Happ, Isaac B. Nelson, Benjamin R. Myers, Susan S. Taylor, Victor L. Ruiz-Perez, Daniela Bertinetti, Jessica Bruystens, Friedrich W. Herberg
The Hedgehog (Hh) cascade is central to development, tissue homeostasis, and cancer. A pivotal step in Hh signal transduction is the activation of GLI transcription factors by the atypical G protein-coupled receptor (GPCR) Smoothened (SMO). How SMO a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dea26f1f8b5789e8b62163a46904f9d
https://doi.org/10.1101/2021.07.05.451193
https://doi.org/10.1101/2021.07.05.451193
Autor:
Jiahao Liang, Jacob L. Capener, Kouki Kawakami, David Grunwald, Asuka Inoue, Jiewei Xu, Ruth Hüttenhain, Dana Klatt Shaw, John T. Happ, Ishan Deshpande, Isaac B. Nelson, Sara L. Stubben, Danielle S. Hedeen, Benjamin R. Myers, Aashish Manglik, Ju Fen Zhu, Nevan J. Krogan, Corvin D. Arveseth, Madison F. Walker
Publikováno v:
PLoS biology, vol 19, iss 4
PLoS Biology
PLoS Biology, Vol 19, Iss 4, p e3001191 (2021)
PLoS Biology
PLoS Biology, Vol 19, Iss 4, p e3001191 (2021)
The Hedgehog (Hh) pathway is essential for organ development, homeostasis, and regeneration. Dysfunction of this cascade drives several cancers. To control expression of pathway target genes, the G protein–coupled receptor (GPCR) Smoothened (SMO) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d2a619f7ac028a3d571337cec82c2f
https://escholarship.org/uc/item/0w43z8d9
https://escholarship.org/uc/item/0w43z8d9
Autor:
John T. Happ, Ishan Deshpande, Isaac B. Nelson, Jiahao Liang, Benjamin R. Myers, Ju-Fen Zhu, Aashish Manglik, Nevan J. Krogan, Danielle S. Hedeen, Jacob L. Capener, Dana Klatt Shaw, Corvin D. Arveseth, Ruth Huttenhain, Sara L. Stubben, David Grunwald, Madison F. Walker, Jiewei Xu
The Hedgehog (Hh) pathway is essential for organ development, homeostasis, and regeneration. Dysfunction of this cascade drives several cancers. To control expression of pathway target genes, the G protein-coupled receptor (GPCR) Smoothened (SMO) act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b14f6e66c1aaf784dc352fe5eb49d880
https://doi.org/10.1101/2020.07.01.183079
https://doi.org/10.1101/2020.07.01.183079