Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Isaac B. Falconer"'
Autor:
Manuel Jose Marte, Erin Carpenter, Isaac B. Falconer, Michael Scimeca, Fatemeh Abdollahi, Claudia Peñaloza, Swathi Kiran
Publikováno v:
Frontiers in Psychology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/411d057ed2aa49e0b474cd9663fde37f
Autor:
Aaron Griffin, Robert S. Hodges, Parker J. Nichols, Liliya Vugmeyster, Christopher J. McKnight, Beat Vögeli, Isaac B. Falconer, Colin T. Mant
Publikováno v:
Protein Sci
We have investigated the effect of deuteration of non‐exchangeable protons on protein global thermal stability, hydrophobicity, and local flexibility using well‐known thermostable model systems such as the villin headpiece subdomain (HP36) and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bb9fdd1283873977cb67841bda483e
https://europepmc.org/articles/PMC7314392/
https://europepmc.org/articles/PMC7314392/
Publikováno v:
The Journal of Physical Chemistry B. 121:7267-7275
Aromatic residues are important markers of dynamical changes in proteins’ hydrophobic cores. In this work we investigated the dynamics of the F19 side-chain in the core of amyloid fibrils across a wide temperature range of 300 to 140 K. We utilized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9c3f01aa7e5a2b905a0e4385afa05b8
https://doi.org/10.1021/acs.jpcb.7b04726
https://doi.org/10.1021/acs.jpcb.7b04726
Publikováno v:
The journal of physical chemistry. B. 121(30)
Aromatic residues are important markers of dynamical changes in proteins’ hydrophobic cores. In this work we investigated the dynamics of the F19 side-chain in the core of amyloid fibrils across a wide temperature range of 300 to 140 K. We utilized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee92aa336c76f12403a928ef27bbde9b
https://pubmed.ncbi.nlm.nih.gov/28699757
https://pubmed.ncbi.nlm.nih.gov/28699757
Autor:
Isaac B. Falconer, Matthew A. Clark, Gina L. Hoatson, Wei Qiang, Dmitry Ostrovsky, Liliya Vugmeyster
Publikováno v:
Biophysical journal. 111(10)
Amyloid- β (A β ) peptide is the major component of plaques found in Alzheimer's disease patients. Using solid-state 2 H NMR relaxation performed on selectively deuterated methyl groups, we probed the dynamics in the threefold symmetric and twofold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0d77ce2816f2052d5e1dd0981b99cf
https://pubmed.ncbi.nlm.nih.gov/27851938
https://pubmed.ncbi.nlm.nih.gov/27851938
Autor:
Gina L. Hoatson, Donald L. Gantz, Dmitry Ostrovsky, Liliya Vugmeyster, Wei Qiang, Isaac B. Falconer, Matthew A. Clark
Publikováno v:
The Journal of biological chemistry. 291(35)
Amyloid fibril deposits found in Alzheimer disease patients are composed of amyloid-β (Aβ) protein forming a number of hydrophobic interfaces that are believed to be mostly rigid. We have investigated the μs-ms time-scale dynamics of the intra-str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65dbd12f0eed62e36e2153a99b9e6712
https://pubmed.ncbi.nlm.nih.gov/27402826
https://pubmed.ncbi.nlm.nih.gov/27402826