Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Isa N. Cruz"'
Autor:
Ana Rita Angelino, Min Yang, Helen M. Coley, Isa N. Cruz, Holger B. Kramer, Thumuluru Kavitah Madhuri, Nur Arnida Mohammed Safuwan
Publikováno v:
Cancer Genomics & Proteomics. 14:35-52
Background: Carboplatin and paclitaxel form the cornerstone of chemotherapy for epithelial ovarian cancer, however, drug resistance to these agents continues to present challenges. Despite extensive research, the mechanisms underlying this resistance
Publikováno v:
Analytical Biochemistry. 438:107-109
Heat shock protein 90 (Hsp90) is an attractive cancer target that possesses two potential binding domains at the C and N termini. Nevertheless, assays that can reliably distinguish between the C- and N-terminal Hsp90 inhibitors and quantitatively cha
Autor:
J Szary, T. Mannan, Hong Wan, Edel A. O'Toole, Ahmad Waseem, Ferran Valderrama, M Unadkat, Louise Brown, M Yang, Isa N. Cruz, E. Gunic
Publikováno v:
Oncogene. 33(18)
Desmoglein 3 (Dsg3), the pemphigus vulgaris antigen, has recently been shown to be upregulated in squamous cell carcinoma (SCC) and has been identified as a good tumor-specific marker for clinical staging of cervical sentinel lymph nodes in head and
Glycomimetic affinity-enrichment proteomics identifies partners for a clinically-utilized iminosugar
Autor:
Sarah E. Lloyd, Benjamin G. Davis, Frances M. Platt, Aarnoud C. van der Spoel, C. Celeste Chuang, Isa N. Cruz, Holger B. Kramer, Conor S. Barry, Min Yang
Publikováno v:
Chemical Science. 4:3442
Widescale evaluation of interacting partners for carbohydrates is an underexploited area. Probing of the 'glyco-interactome' has particular relevance given the lack of direct genetic control of glycoconjugate biosynthesis. Here we design, create and