Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Isa Muñoz-Arias"'
Autor:
Nicole L.K. Galloway, Gilad Doitsh, Kathryn M. Monroe, Zhiyuan Yang, Isa Muñoz-Arias, David N. Levy, Warner C. Greene
Publikováno v:
Cell Reports, Vol 12, Iss 10, Pp 1555-1563 (2015)
The progressive depletion of CD4 T cells underlies clinical progression to AIDS in untreated HIV-infected subjects. Most dying CD4 T cells correspond to resting nonpermissive cells residing in lymphoid tissues. Death is due to an innate immune respon
Externí odkaz:
https://doaj.org/article/83ab6fe338854f03acbeae99c079790c
Autor:
Gilad Doitsh, Eytan Herzig, Isa Muñoz-Arias, Xiaoyu Luo, Zachary W. Grimmett, Warner C. Greene
Publikováno v:
Journal of virology, vol 93, iss 24
J Virol
J Virol
Human immunodeficiency virus type 2 (HIV-2) infection results in a milder course of disease and slower progression to AIDS than does HIV-1. We hypothesized that this difference may be due to degradation of the sterile alpha motif and HD domain 1 (SAM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1ff21c3d8c054539b811be44c21c1f
https://escholarship.org/uc/item/9t1389g1
https://escholarship.org/uc/item/9t1389g1
Autor:
Orlando Zepeda, Zhiyuan Yang, Hiroyu Hatano, Gilad Doitsh, Xin Geng, Stefanie Sowinski, Warner C. Greene, Kathryn M. Monroe, Peter W. Hunt, Isa Muñoz-Arias, Nicole L. K. Galloway
Publikováno v:
Nature. 505:509-514
The pathway causing CD4 T-cell death in HIV-infected hosts remains poorly understood although apoptosis has been proposed as a key mechanism. We now show that caspase-3-mediated apoptosis accounts for the death of only a small fraction of CD4 T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53bbe041f92c069059ffc034dff1cbaa
https://doi.org/10.1038/nature12940
https://doi.org/10.1038/nature12940
Autor:
Warner C. Greene, Isa Muñoz-Arias, Debbie S. Ruelas, Gilad Doitsh, Zhiyuan Yang, Stefanie Sowinski
Publikováno v:
Cell host & microbe, vol 18, iss 4
SummaryProgression to AIDS is driven by CD4 T cell depletion, mostly involving pyroptosis elicited by abortive HIV infection of CD4 T cells in lymphoid tissues. Inefficient reverse transcription in these cells leads to cytoplasmic accumulation of vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a1dc4cac54c1947a8f90e77b4a96e1
https://europepmc.org/articles/PMC4627664/
https://europepmc.org/articles/PMC4627664/
Autor:
Nicole L. K. Galloway, Isa Muñoz-Arias, Kathryn M. Monroe, David N. Levy, Gilad Doitsh, Zhiyuan Yang, Warner C. Greene
Publikováno v:
Cell reports, vol 12, iss 10
Cell Reports, Vol 12, Iss 10, Pp 1555-1563 (2015)
Cell Reports, Vol 12, Iss 10, Pp 1555-1563 (2015)
SummaryThe progressive depletion of CD4 T cells underlies clinical progression to AIDS in untreated HIV-infected subjects. Most dying CD4 T cells correspond to resting nonpermissive cells residing in lymphoid tissues. Death is due to an innate immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67df9e77d8cf0da3d9d23db580579063
https://escholarship.org/uc/item/6580n0mz
https://escholarship.org/uc/item/6580n0mz
Autor:
Warner C. Greene, Stefanie Sowinski, Hiroyu Hatano, Zhiyuan Yang, Gilad Doitsh, Kathryn M. Monroe, Nicole L. K. Galloway, Peter W. Hunt, Xin Geng, Isa Muñoz-Arias, Orlando Zepeda
Publikováno v:
Nature. 544:124-124
Nature 505, 509–514 (2014); doi:10.1038/nature12940 In Extended Data Fig. 1 of this Article, the flow data presented in the ‘NL4-3 No Drugs’ panels were inadvertently duplicated in the ‘89.6 (X4/R5) No Drugs’ panels. A revised figure contai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8c16197109ae520c04404984a37a74b
https://doi.org/10.1038/nature22066
https://doi.org/10.1038/nature22066
Autor:
Nicole L. K. Galloway, Isa Muñoz-Arias, Kathryn M. Monroe, Xin Geng, Zhiyuan Yang, Warner C. Greene, Gilad Doitsh
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 67:63
Author(s): Galloway, Nicole Louise Katherine | Advisor(s): Ott, Melanie; Greene, Warner C | Abstract: The pathway causing CD4 T-cell death in HIV-infected hosts remains poorly understood although apoptosis has been proposed as a key player. Our studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11d7b295c9f56887cedccebac36ce9f9
https://doi.org/10.1097/01.qai.0000456111.36935.29
https://doi.org/10.1097/01.qai.0000456111.36935.29