Výsledky vyhledávání - "Isa D. L. Gomes"

Gene Editing in the Ascidian Phallusia mammillata and Tail Nerve Cord Formation

Autor: Rémi Dumollard, Isa D. L. Gomes, Celine Hebras, Alex McDougall

Publikováno v: Gene Editing in the Ascidian Phallusia mammillata and Tail Nerve Cord Formation.
Gene Editing in the Ascidian Phallusia mammillata and Tail Nerve Cord Formation., pp.217-230, 2021, ⟨10.1007/978-1-0716-0974-3_13⟩
Developmental Biology of the Sea Urchin and Other Marine Invertebrates
Methods in Molecular Biology ISBN: 9781071609736
Methods in Molecular Biology
Methods in Molecular Biology-Developmental Biology of the Sea Urchin and Other Marine Invertebrates
Developmental Biology of the Sea Urchin and Other Marine Invertebrates, 2219, Springer US; Springer US, pp.217-230, 2021, Methods in Molecular Biology, ⟨10.1007/978-1-0716-0974-3_13,⟩

International audience; Functional approaches for studying embryonic development have greatly advanced thanks to the CRISPR-Cas9 gene editing technique. Previously practiced in just a few organisms, these knockout techniques are now widely applied. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe901f9890d61b5f5e3603e3fbdb5576
https://hal.archives-ouvertes.fr/hal-03025300

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High-content analysis of larval phenotypes for the screening of xenobiotic toxicity using Phallusia mammillata embryos

Autor: Manon Brunet, Rémi Dumollard, Celine Hebras, Lydia Besnardeau, Ievgeniia Gazo, Thierry Savy, Nadine Peyriéras, Alex McDougall, Olena Shaliutina, Isa D. L. Gomes, Sameh Benaicha

Publikováno v: Aquatic Toxicology
Aquatic Toxicology, Elsevier, 2021, 232, pp.105768. ⟨10.1016/j.aquatox.2021.105768⟩
Aquatic Toxicology, 2021, 232, pp.105768. ⟨10.1016/j.aquatox.2021.105768⟩

International audience; In recent years, pollution of surface waters with xenobiotic compounds became an issue of concern in society and has been the object of numerous studies. Most of these xenobiotic compounds are man-made molecules and some of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82cad594d9906bf8d91c2c6b746e78f1
https://hal.archives-ouvertes.fr/hal-03458263

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Nuclear Receptors and Development of Marine Invertebrates

Autor: Laura Canesi, Isa D. L. Gomes, Michael Schubert, A. Miglioli, Rémi Dumollard

Publikováno v: Genes
Genes, MDPI, 2021, 12 (1), pp.83. ⟨10.3390/genes12010083⟩
Genes, Vol 12, Iss 83, p 83 (2021)

International audience; Nuclear Receptors (NRs) are a superfamily of transcription factors specific to metazoans that have the unique ability to directly translate the message of a signaling molecule into a transcriptional response. In vertebrates, N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7401683d84d0685e5b73192215d77c96
https://hal.archives-ouvertes.fr/hal-03374744/document

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Potential roles of nuclear receptors in mediating neurodevelopmental toxicity of known endocrine-disrupting chemicals in ascidian embryos

Autor: Alex McDougall, Isa D. L. Gomes, Ievgeniia Gazo, Lydia Besnardeau, Rémi Dumollard, Celine Hebras

Publikováno v: Molecular Reproduction and Development
Molecular Reproduction and Development, Wiley, 2019, 86 (10), pp.1333-1347. ⟨10.1002/mrd.23219⟩

Endocrine Disrupting Chemicals (EDCs) are molecules able to interfere with the vertebrate hormonal system in different ways, a major one being the modification of the activity of nuclear receptors (NRs). Several NRs are expressed in the vertebrate br

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a8130918070d03c758e44cd1b140dd
https://pubmed.ncbi.nlm.nih.gov/31215734

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Ascidians: An Emerging Marine Model for Drug Discovery and Screening

Autor: Alex McDougall, Rémi Dumollard, Lydia Besnardeau, Isa D. L. Gomes, Ievgeniia Gazo

Publikováno v: Current Topics in Medicinal Chemistry
Current Topics in Medicinal Chemistry, Bentham Science Publishers, 2017, 17 (18), ⟨10.2174/1568026617666170130104922⟩
Current Topics in Medicinal Chemistry, 2017, 17 (18), ⟨10.2174/1568026617666170130104922⟩

Ascidians (tunicates; sea squirts) are marine animals which provide a source of diverse, bioactive natural products, and a model for toxicity screenings. Compounds isolated from ascidians comprise an approved anti-tumor drug and many others are poten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633ac75e75b56691ada39dfd85041abf
https://hal.archives-ouvertes.fr/hal-02115692

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