Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Iryna Rusanova"'
Autor:
Laura Martinez-Ruiz, Javier Florido, César Rodriguez-Santana, Alba López-Rodríguez, Ana Guerra-Librero, Beatriz I. Fernández-Gil, Patricia García-Tárraga, José Manuel Garcia-Verdugo, Felix Oppel, Holger Sudhoff, David Sánchez-Porras, Amadeo Ten-Steve, José Fernández-Martínez, Pilar González-García, Iryna Rusanova, Darío Acuña-Castroviejo, Víctor Carriel, Germaine Escames
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115518- (2023)
Head and neck squamous cell carcinoma present a high mortality rate. Melatonin has been shown to have oncostatic effects in different types of cancers. However, inconsistent results have been reported for in vivo applications. Consequently, an altern
Externí odkaz:
https://doaj.org/article/88cf62c5f1de4102ac70780b346f856d
Autor:
Ayauly Duisenbek, Gabriela C. Lopez-Armas, Miguel Pérez, María D. Avilés Pérez, José Miguel Aguilar Benitez, Víctor Roger Pereira Pérez, Juan Gorts Ortega, Arailym Yessenbekova, Nurzhanyat Ablaikhanova, Germaine Escames, Darío Acuña-Castroviejo, Iryna Rusanova
Publikováno v:
Antioxidants, Vol 12, Iss 6, p 1290 (2023)
A common denominator of metabolic diseases, including type 2 diabetes Mellitus, dyslipidemia, and atherosclerosis, are elevated oxidative stress and chronic inflammation. These complex, multi-factorial diseases are caused by the detrimental interacti
Externí odkaz:
https://doaj.org/article/ce7172bd4b5c4b72b8f1f6e440943edc
Autor:
Paula Aranda-Martínez, José Fernández-Martínez, Yolanda Ramírez-Casas, César Rodríguez-Santana, Iryna Rusanova, Germaine Escames, Darío Acuña-Castroviejo
Publikováno v:
Antioxidants, Vol 12, Iss 4, p 954 (2023)
Beyond sleep/wake, clock genes regulate the daily rhythms of melatonin production, motor activity, innate immunity, and mitochondrial dynamics, among others. All these rhythms are affected in Parkinson’s disease (PD), suggesting that chronodisrupti
Externí odkaz:
https://doaj.org/article/3b11a74dc01b42df8dec33346f90092c
Autor:
Gabriela C. López-Armas, Arailym Yessenbekova, Rocío E. González-Castañeda, Kevin J. Arellano-Arteaga, Ana Guerra-Librero, Nurzhanyat Ablaikhanova, Javier Florido, Germaine Escames, Darío Acuña-Castroviejo, Iryna Rusanova
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1675 (2022)
The development of type 2 diabetes mellitus (T2DM) vascular complications (VCs) is associated with oxidative stress and chronic inflammation and can result in endothelial dysfunctions. Circulating microRNAs play an important role in epigenetic regula
Externí odkaz:
https://doaj.org/article/aeb8335b24524511a04bcd5e78dc78d9
Autor:
Javier Florido, César Rodriguez-Santana, Laura Martinez-Ruiz, Alba López-Rodríguez, Darío Acuña-Castroviejo, Iryna Rusanova, Germaine Escames
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1621 (2022)
Reactive oxygen species (ROS) constitute a group of highly reactive molecules that have evolved as regulators of important signaling pathways. In this context, tumor cells have an altered redox balance compared to normal cells, which can be targeted
Externí odkaz:
https://doaj.org/article/34fb04e233af4c3794473162c93d789a
Autor:
Ramy K. A. Sayed, Marisol Fernández-Ortiz, Ibtissem Rahim, José Fernández-Martínez, Paula Aranda-Martínez, Iryna Rusanova, Laura Martínez-Ruiz, Reem M. Alsaadawy, Germaine Escames, Darío Acuña-Castroviejo
Publikováno v:
Antioxidants, Vol 10, Iss 8, p 1269 (2021)
To investigate the role of NLRP3 inflammasome in cardiac aging, we evaluate here morphological and ultrastructural age-related changes of cardiac muscles fibers in wild-type and NLRP3-knockout mice, as well as studying the beneficial effect of melato
Externí odkaz:
https://doaj.org/article/690bb609b0984fca897b29e060d76928
Autor:
Ana Guerra-Librero, Beatriz I. Fernandez-Gil, Javier Florido, Laura Martinez-Ruiz, César Rodríguez-Santana, Ying-Qiang Shen, José M. García-Verdugo, Alba López-Rodríguez, Iryna Rusanova, Alfredo Quiñones-Hinojosa, Darío Acuña-Castroviejo, Jordi Marruecos, Tomás De Haro, Germaine Escames
Publikováno v:
Antioxidants, Vol 10, Iss 4, p 603 (2021)
Metabolic reprogramming, which is characteristic of cancer cells that rapidly adapt to the hypoxic microenvironment and is crucial for tumor growth and metastasis, is recognized as one of the major mechanisms underlying therapeutic resistance. Mitoch
Externí odkaz:
https://doaj.org/article/aa54229d03994e9e854f4b5bf863ed22
Autor:
Ramy KA Sayed, Marisol Fernández-Ortiz, José Fernández-Martínez, Paula Aranda Martínez, Ana Guerra-Librero, César Rodríguez-Santana, Tomás de Haro, Germaine Escames, Darío Acuña-Castroviejo, Iryna Rusanova
Publikováno v:
Antioxidants, Vol 10, Iss 4, p 524 (2021)
Muscular aging is a complex process and underlying physiological mechanisms are not fully clear. In recent years, the participation of the NF-kB pathway and the NLRP3 inflammasome in the chronic inflammation process that accompanies the skeletal musc
Externí odkaz:
https://doaj.org/article/d94cb5ddfce94be99abd30335ca2ba48
Autor:
Germaine Escames, José Fernández-Martínez, Ana Guerra-Librero, Paula Aranda-Martínez, Iryna Rusanova, Darío Acuña-Castroviejo, Ramy K. A. Sayed, Marisol Fernández-Ortiz, Bahia Djerdjouri, Ibtissem Rahim
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 394:261-277
Melatonin improved the outcome of septic cardiomyopathy by inhibiting NLRP3 priming induced by reactive oxygen species. To get insights into these events, we studied the melatonin/Nrf2 antioxidant pathways during sepsis in the heart of NLRP3-deficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5d8c16aae950ff819b9f593db9ef649
https://doi.org/10.1007/s00210-020-01972-5
https://doi.org/10.1007/s00210-020-01972-5
Autor:
Marisol Fernández-Ortiz, Ramy K. A. Sayed, Yolanda Román-Montoya, María Ángeles Rol de Lama, José Fernández-Martínez, Yolanda Ramírez-Casas, Javier Florido-Ruiz, Iryna Rusanova, Germaine Escames, Darío Acuña-Castroviejo
Publikováno v:
Digibug. Repositorio Institucional de la Universidad de Granada
instname
International Journal of Molecular Sciences; Volume 23; Issue 12; Pages: 6846
instname
International Journal of Molecular Sciences; Volume 23; Issue 12; Pages: 6846
Age and age-dependent inflammation are two main risk factors for cardiovascular diseases. Aging can also affect clock gene-related impairments such as chronodisruption and has been linked to a decline in melatonin synthesis and aggravation of the NF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332a697f10a0b52cc8dc9544e9e73d71
http://hdl.handle.net/10481/75989
http://hdl.handle.net/10481/75989
