Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Iryna Rastarhuyeva"'
Publikováno v:
Archives of Biochemistry and Biophysics. 466:242-249
Low levels of hydrogen peroxide (H(2)O(2)) are mitogenic to mammalian cells and stimulate the hyperphosphorylation of heterogeneous nuclear ribonucleoprotein C (hnRNP-C) by protein kinase CK1alpha. However, the mechanisms by which CK1alpha is regulat
Publikováno v:
The FASEB Journal. 21
Autor:
Suzanne George, Tim Akhurst, Jeffrey A. Morgan, Jeffrey T. Yap, George D. Demetri, Gauri Bhuchar, Mary Louise Keohan, Iryna Rastarhuyeva, A. D. Van Den Abbeele, Robert G. Maki
Publikováno v:
Journal of Clinical Oncology. 26:10529-10529
10529 Background: Sunitinib malate is a multitargeted tyrosine kinase inhibitor of KIT, PDGFRs, VEGFRs, FLT3, CSF-1R and RET approved for the treatment of imatinib-resistant/intolerant GIST and adv...
Autor:
A. D. Van Den Abbeele, Philip W. Kantoff, Iryna Rastarhuyeva, Robert W. Ross, William Oh, John Kim, Mary-Ellen Taplin, Charles J. Ryan, Jeffrey T. Yap, Judith Manola
Publikováno v:
Journal of Clinical Oncology. 26:5069-5069
5069 Background: Improved therapy for CRPC remains an urgent need. CRPCs have frequent loss of the tumor suppressor gene PTEN with increased expression of mTOR driving tumor growth. R is a novel mT...
Autor:
Judy Garber, Sapna Syngal, Joseph F. Fraumeni, Katherine A. Schneider, Lisa DiGianni, Iryna Rastarhuyeva, Serena Masciari, Lisa Diller, Jeffrey T. Yap, Frederick P. Li, Annick D. Van den Abbeele
Publikováno v:
JAMA. 299:1315
Context Individuals with Li-Fraumeni syndrome (LFS) have an inherited cancer predisposition to a diverse array of malignancies beginning early in life; survivors of one cancer have a markedly elevated risk of additional primary tumors. The underlying
Autor:
Iryna Rastarhuyeva, Kimberly Phillips, Kristen E. Stevenson, Jyothi P. Jagannathan, Arnold S. Freedman, Jennifer C. Clark, Donna Neuberg, Ronald W. Takvorian, Annick D. Van den Abbeele, David C. Fisher, Yulia Melenevsky, Jennifer R. Brown
Publikováno v:
Blood. 110:2331-2331
Follicular lymphoma is the most common low-grade lymphoma and incurable with conventional therapies. In recent years, increased use of FDG-PET (PET) scanning in aggressive lymphomas has led to its application in follicular lymphoma, despite a lack of