Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Iryna Ostash"'
Autor:
Borys Dolya, Olena Hryhorieva, Khrystyna Sorochynska, Maria Lopatniuk, Iryna Ostash, Vasylyna-Marta Tseduliak, Eva Baggesgaard Sterndorff, Tue Sparholt Jørgensen, Tetiana Gren, Yuriy Dacyuk, Tilmann Weber, Andriy Luzhetskyy, Victor Fedorenko, Bohdan Ostash
Publikováno v:
Microorganisms, Vol 11, Iss 5, p 1176 (2023)
Streptomyces albidoflavus J1074 is a popular platform to discover novel natural products via the expression of heterologous biosynthetic gene clusters (BGCs). There is keen interest in improving the ability of this platform to overexpress BGCs and, c
Externí odkaz:
https://doaj.org/article/074ec5aa5e7f49d4be3db5ee7c5b30f6
Autor:
Oleksandr Yushchuk, Iryna Ostash, Eva Mösker, Iryna Vlasiuk, Maksym Deneka, Christian Rückert, Tobias Busche, Victor Fedorenko, Jörn Kalinowski, Roderich D. Süssmuth, Bohdan Ostash
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Actinobacteria are among the most prolific sources of medically and agriculturally important compounds, derived from their biosynthetic gene clusters (BGCs) for specialized (secondary) pathways of metabolism. Genomics witnesses that the majo
Externí odkaz:
https://doaj.org/article/057a7057442146c8ad1690394f59b75a
Autor:
Oksana Koshla, Lea-Marie Vogt, Oleksandr Rydkin, Yuliia Sehin, Iryna Ostash, Mark Helm, Bohdan Ostash
Publikováno v:
J Bacteriol
Actinobacterial genus Streptomyces (streptomycetes) represents one of the largest cultivable group of bacteria famous for their ability to produce valuable specialized (secondary) metabolites. Regulation of secondary metabolic pathways inextricably c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48f992c62f39613aafcba1c9b577733
https://doi.org/10.1128/jb.00294-22
https://doi.org/10.1128/jb.00294-22
Autor:
Vasylyna-Marta Tseduliak, Borys Dolia, Iryna Ostash, Maria Lopatniuk, Tobias Busche, Kozo Ochi, Jörn Kalinowski, Andriy Luzhetskyy, Victor Fedorenko, Bohdan Ostash
Publikováno v:
Journal of applied genetics.
Streptomyces albus J1074 is one of the most popular heterologous expression platforms among streptomycetes. Identification of new genes and mutations that influence specialized metabolism in this species is therefore of great applied interest. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59bb1f9ed0a9bdd4a4118a1a1a350ccb
https://pubmed.ncbi.nlm.nih.gov/36417169
https://pubmed.ncbi.nlm.nih.gov/36417169
Autor:
Roderich D. Süssmuth, Oksana Koshla, Bohdan Ostash, Volodymyr Kravets, Iryna Ostash, Yuriy Dacyuk
Publikováno v:
Folia Microbiologica. 65:1009-1015
Proteins MiaA and MiaB catalyze sequential isopentenylation and methylthiolation, respectively, of adenosine residue in 37th position of tRNAXXA. The mia mutations were recently shown by us to affect secondary metabolism and morphology of Streptomyce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a25c981aac2136796f406151ba44dda2
https://doi.org/10.1007/s12223-020-00811-7
https://doi.org/10.1007/s12223-020-00811-7
Autor:
Atsushi Tsugita, Shiro Uehara, Takashi Matsui, Takeshi Yokoyama, Iryna Ostash, Maksym Deneka, Subbarao Yalamanchili, Clay S. Bennett, Yoshikazu Tanaka, Bohdan Ostash
Publikováno v:
The FEBS journalReferences. 289(19)
Landomycin A (LaA) is the largest member of the landomycin group of angucyclic polyketides. Its unusual structure and strong anticancer properties have attracted great interest from chemists and biologists alike. This, in particular, has led to a det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc78c448ebc23a570a46338e0ae93ecd
https://pubmed.ncbi.nlm.nih.gov/35429224
https://pubmed.ncbi.nlm.nih.gov/35429224
Autor:
null Atsushi Tsugita, null Shiro Uehara, null Takashi Matsui, null Takeshi Yokoyama, null Iryna Ostash, null Maksym Deneka, null Subbarao Yalamanchili, null Clay S. Bennett, null Yoshikazu Tanaka, null Bohdan Ostash
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::155f6ef41a79f2ffb7812eb5d14ca9db
https://doi.org/10.1111/febs.16460/v2/response1
https://doi.org/10.1111/febs.16460/v2/response1
Autor:
Sofia Melnyk, Anastasia Stepanyshyn, Oleksandr Yushchuk, Michael Mandler, Iryna Ostash, Oksana Koshla, Victor Fedorenko, Daniel Kahne, Bohdan Ostash
Publikováno v:
Appl Microbiol Biotechnol
Streptomyces roseochromogenes NRRL 3504 is best known as a producer of clorobiocin, a DNA replication inhibitor from the aminocoumarin family of antibiotics. This natural product currently draws attention as a promising adjuvant for co-application wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321655e46364cc4812b2bf375d2dd1e5
https://europepmc.org/articles/PMC9528727/
https://europepmc.org/articles/PMC9528727/
Autor:
Oksana Koshla, Gunilla Jäger, Andriy Luzhetskyy, Iryna Ostash, Bohdan Ostash, Maksym Myronovskyi, Yuriy Dacyuk, Anders S. Byström, Oleksandr Yushchuk, Leif A. Kirsebom, Roderich D. Süssmuth
Publikováno v:
Molecular Microbiology. 112:249-265
Members of actinobacterial genus Streptomyces possess a sophisticated life cycle and are the deepest source of bioactive secondary metabolites. Although morphogenesis and secondary metabolism are s ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8307d4a615d46f50352f5c443414910
https://doi.org/10.1111/mmi.14266
https://doi.org/10.1111/mmi.14266
Autor:
Bohdan Ostash, Tobias Busche, Iryna Ostash, Victor Fedorenko, Jörn Kalinowski, Pavlo Hrab, Christian Rückert, Oleksandr Yushchuk
Publikováno v:
3 Biotech. 11
Streptomyces cyanogenus S136 is the only known producer of landomycin A (LaA), one of the founding members of angucycline family of aromatic polyketides. LaA displays potent anticancer activities which has made this natural product a target of numero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8805f80c30fd382497772cb0e26c196
https://doi.org/10.1007/s13205-021-02834-4
https://doi.org/10.1007/s13205-021-02834-4