Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Iryna Leshchyns'ka"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Cell adhesion molecules (CAMs) mediate interactions of neurons with the extracellular environment by forming adhesive bonds with CAMs on adjacent membranes or via binding to proteins of the extracellular matrix. Binding of CAMs to their extracellular
Externí odkaz:
https://doaj.org/article/23f742268e1945dbba8470fe3a2ff3a8
Autor:
Daria Guseva, Igor Jakovcevski, Andrey Irintchev, Iryna Leshchyns’ka, Vladimir Sytnyk, Evgeni Ponimaskin, Melitta Schachner
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
The close homolog of L1 (CHL1) is a cell adhesion molecule involved in regulation of neuronal differentiation and survival, neurite outgrowth and axon guidance during development. In the mature nervous system, CHL1 regulates synaptic activity and pla
Externí odkaz:
https://doaj.org/article/6c4766a5061a4f95967ab518ce741a4e
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Immunoglobulin superfamily (IgSF) cell adhesion molecules (CAMs) are cell surface glycoproteins that not only mediate interactions between neurons but also between neurons and other cells in the nervous system. While typical IgSF CAMs are transmembra
Externí odkaz:
https://doaj.org/article/bb6fdd9970454421b57b57a98c51e103
Autor:
Iryna Leshchyns’ka, Vladimir Sytnyk
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Alzheimer’s disease (AD) is a neurodegenerative brain disorder associated with the loss of synapses between neurons in the brain. Synaptic cell adhesion molecules are cell surface glycoproteins which are expressed at the synaptic plasma membranes o
Externí odkaz:
https://doaj.org/article/fdeb622bbfac4bfc8bce7d7366e107a8
Autor:
Iryna Leshchyns’ka, Vladimir Sytnyk
Publikováno v:
Bio-Protocol, Vol 3, Iss 15 (2013)
Growth cones are motile structures at the tips of growing neurites, which play an essential role in regulation of growth and navigation of growing axons and dendrites of neurons in the developing nervous system. This protocol describes isolation of g
Externí odkaz:
https://doaj.org/article/d546c6f789a049098e4dbcf84bb85060
Autor:
Aksana Andreyeva, Iryna Leshchyns'ka, Michael Knepper, Christian Betzel, Lars Redecke, Vladimir Sytnyk, Melitta Schachner
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12018 (2010)
Proteins constituting the presynaptic machinery of vesicle release undergo substantial conformational changes during the process of exocytosis. While changes in the conformation make proteins vulnerable to aggregation and degradation, little is known
Externí odkaz:
https://doaj.org/article/9c147bfce0494c22af24aec9ac5e4fc0
Autor:
Ryan Keable, Shangfeng Hu, Grant Pfundstein, Irina Kozlova, Feifei Su, Ximing Du, Hongyuan Yang, Jenny Gunnersen, Melitta Schachner, Iryna Leshchyns’ka, Vladimir Sytnyk
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(11)
Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1), also known as β-secretase, is an aspartic protease. The sorting of this enzyme into Rab11-positive recycling endosomes regulates the BACE1-mediated cleavage of its substrates, however, t
Publikováno v:
Cellular and Molecular Life Sciences. 78:93-116
The success of investigations on the structure and function of the genome (genomics) has been paralleled by an equally awesome progress in the analysis of protein structure and function (proteomics). We propose that the investigation of carbohydrate
Autor:
Ashton Curry-Hyde, Ryan Keable, Nicola Bliim, Lachlan G. Gray, Vladimir Sytnyk, Michael Janitz, Bei Jun Chen, Iryna Leshchyns'ka
Publikováno v:
Genomics. 111:1676-1686
Long term potentiation (LTP) is a form of synaptic plasticity. In the present study LTP was induced via activation of synaptic NMDA receptors in primary hippocampal neuron cultures from neonate mice and RNA was isolated for RNA sequencing at 20 min f
Publikováno v:
Cellular and molecular life sciences : CMLS. 78(1)
The success of investigations on the structure and function of the genome (genomics) has been paralleled by an equally awesome progress in the analysis of protein structure and function (proteomics). We propose that the investigation of carbohydrate