Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Iryna Bohovych"'
Autor:
Jonathan V. Dietz, Mathilda M. Willoughby, Robert B. Piel, III, Teresa A. Ross, Iryna Bohovych, Hannah G. Addis, Jennifer L. Fox, William N. Lanzilotta, Harry A. Dailey, James A. Wohlschlegel, Amit R. Reddi, Amy E. Medlock, Oleh Khalimonchuk
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102125- (2021)
Heme is an essential cofactor required for a plethora of cellular processes in eukaryotes. In metazoans the heme biosynthetic pathway is typically partitioned between the cytosol and mitochondria, with the first and final steps taking place in the mi
Externí odkaz:
https://doaj.org/article/b5b8982ff5e84ce3a38023b6ecfea0bd
Autor:
Jinglin L. Xie, Iryna Bohovych, Erin O.Y. Wong, Jean-Philippe Lambert, Anne-Claude Gingras, Oleh Khalimonchuk, Leah E. Cowen, Michelle D. Leach
Publikováno v:
Microbial Cell, Vol 4, Iss 10, Pp 342-361 (2017)
Mitochondria underpin metabolism, bioenergetics, signalling, development and cell death in eukaryotes. Most of the ~1,000 yeast mitochondrial proteins are encoded in the nucleus and synthesised as precursors in the cytosol, with mitochondrial import
Externí odkaz:
https://doaj.org/article/891dbcaf5aa8497bbad7d3f89244e2e9
Autor:
Annadurai Anandhan, Humberto Rodriguez-Rocha, Iryna Bohovych, Amy M. Griggs, Laura Zavala-Flores, Elsa M. Reyes-Reyes, Javier Seravalli, Lia A. Stanciu, Jaekwon Lee, Jean-Christophe Rochet, Oleh Khalimonchuk, Rodrigo Franco
Publikováno v:
Neurobiology of Disease, Vol 81, Iss , Pp 76-92 (2015)
Gene multiplications or point mutations in alpha (α)-synuclein are associated with familial and sporadic Parkinson's disease (PD). An increase in copper (Cu) levels has been reported in the cerebrospinal fluid and blood of PD patients, while occupat
Externí odkaz:
https://doaj.org/article/f1b5bc5819ef4b71b14e7e20b48bf772
Autor:
Iryna Bohovych, Oleh Khalimonchuk
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 4 (2016)
Normal cellular physiology is critically dependent on numerous mitochondrial activities including energy conversion, cofactor and precursor metabolite synthesis, and regulation of ion and redox homeostasis. Advances in mitochondrial research during t
Externí odkaz:
https://doaj.org/article/d6d0054e5e8340e3a1ccf5c3e1a254b5
Autor:
Doblin Sandai, Zhikang Yin, Laura Selway, David Stead, Janet Walker, Michelle D. Leach, Iryna Bohovych, Iuliana V. Ene, Stavroula Kastora, Susan Budge, Carol A. Munro, Frank C. Odds, Neil A. R. Gow, Alistair J. P. Brown
Publikováno v:
mBio, Vol 6, Iss 1 (2015)
Externí odkaz:
https://doaj.org/article/ee2515d2b7d34c41b4e1904c78a2cd54
Autor:
Despoina Kaloriti, Mette Jacobsen, Zhikang Yin, Miranda Patterson, Anna Tillmann, Deborah A. Smith, Emily Cook, Tao You, Melissa J. Grimm, Iryna Bohovych, Celso Grebogi, Brahm H. Segal, Neil A. R. Gow, Ken Haynes, Janet Quinn, Alistair J. P. Brown
Publikováno v:
mBio, Vol 5, Iss 4 (2014)
ABSTRACT Immune cells exploit reactive oxygen species (ROS) and cationic fluxes to kill microbial pathogens, such as the fungus Candida albicans. Yet, C. albicans is resistant to these stresses in vitro. Therefore, what accounts for the potent antifu
Externí odkaz:
https://doaj.org/article/4dfb09531b17429f9de94c33d6f04296
Autor:
Shahida Shahana, Delma S Childers, Elizabeth R Ballou, Iryna Bohovych, Frank C Odds, Neil A R Gow, Alistair J P Brown
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100390 (2014)
Precise genome modification is essential for the molecular dissection of Candida albicans, and is yielding invaluable information about the roles of specific gene functions in this major fungal pathogen of humans. C. albicans is naturally diploid, un
Externí odkaz:
https://doaj.org/article/e15b872fc57e4447a9c50db0cdf9dfee
Autor:
Doblin Sandai, Zhikang Yin, Laura Selway, David Stead, Janet Walker, Michelle D. Leach, Iryna Bohovych, Iuliana V. Ene, Stavroula Kastora, Susan Budge, Carol A. Munro, Frank C. Odds, Neil A. R. Gow, Alistair J. P. Brown
Publikováno v:
mBio, Vol 3, Iss 6 (2012)
ABSTRACT Microbes must assimilate carbon to grow and colonize their niches. Transcript profiling has suggested that Candida albicans, a major pathogen of humans, regulates its carbon assimilation in an analogous fashion to the model yeast Saccharomyc
Externí odkaz:
https://doaj.org/article/9795abf2995b4a3a8c1aec50890a3d58
Autor:
Jennifer L. Fox, Robert B. Piel, Teresa A. Ross, Hannah G. Addis, Oleh Khalimonchuk, Jonathan V. Dietz, Amit R. Reddi, Amy E. Medlock, Mathilda M. Willoughby, James A. Wohlschlegel, Iryna Bohovych, William N. Lanzilotta, Harry A. Dailey
Publikováno v:
Redox Biology
Redox Biology, Vol 46, Iss, Pp 102125-(2021)
Redox Biology, Vol 46, Iss, Pp 102125-(2021)
Heme is an essential cofactor required for a plethora of cellular processes in eukaryotes. In metazoans the heme biosynthetic pathway is typically partitioned between the cytosol and mitochondria, with the first and final steps taking place in the mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe65aaaa8550b973ddc49787fb00a10a
https://pubmed.ncbi.nlm.nih.gov/34517185
https://pubmed.ncbi.nlm.nih.gov/34517185
Autor:
Mathilda M. Willoughby, Arushi Saini, Iryna Bohovych, Amit R. Reddi, Oleh Khalimonchuk, Jonathan V. Dietz, Amy E. Medlock, Osiris Martinez-Guzman
Publikováno v:
Journal of Cell Science.
Heme is a cofactor and signaling molecule that is essential for much of aerobic life. All heme-dependent processes in eukaryotes require that heme is trafficked from its site of synthesis in the mitochondria to hemoproteins located throughout the cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f04ea186cbbfa0af9457843f5fa9f131
https://doi.org/10.1242/jcs.237917
https://doi.org/10.1242/jcs.237917