Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Irwin Selvam"'
Autor:
Craig A. Hutton, Harshwardhan Poddar, James A. Triccas, Kirsty J. McLean, Gayathri Nagalingam, Andrew W. Munro, Sunnia Rajput, Irwin Selvam, Colin Levy
Publikováno v:
Journal of Medicinal Chemistry. 62:9792-9805
A series of analogues of cyclo(l-tyrosyl-l-tyrosine), the substrate of the Mycobacterium tuberculosis enzyme CYP121, have been synthesized and analyzed by UV-vis and electron paramagnetic resonance spectroscopy and by X-ray crystallography. The intro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e010e8cb9dc0178b58f8c2f260ea7a96
https://doi.org/10.1021/acs.jmedchem.9b01199
https://doi.org/10.1021/acs.jmedchem.9b01199
Autor:
Irwin Selvam, Kjersti Gjerde, Moshe Oren, Kristin Stock, Wytske M. van Weerden, Annika Osswald, Marta Estrada, Erwin R. Boghaert, Ralph Graeser, Varda Rotter, Ronald de Hoogt, Yolanda T. Chong, Wolfgang Sommergruber, Sami Blom, Sylvia Gruenewald, Vítor E. Santo, Suzana Vidic, Albin Rudisch, Yan Stein, Catarina Brito, Sharath C. Arundkar, Michaël Barbier
Publikováno v:
Scientific Reports, 6:28951. Nature Publishing Group
Scientific Reports
Scientific Reports
Two-dimensional (2D) cell cultures growing on plastic do not recapitulate the three dimensional (3D) architecture and complexity of human tumors. More representative models are required for drug discovery and validation. Here, 2D culture and 3D mono-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2c65fe459a0b7c6ae6deeba9d33774
https://pure.eur.nl/en/publications/4fd29f1e-e004-4b01-9b3a-3c4587080687
https://pure.eur.nl/en/publications/4fd29f1e-e004-4b01-9b3a-3c4587080687
Autor:
Alessia Ruggiero, Loes M. J. Kroon-Batenburg, Edoardo L. M. Gelardi, Luigi Vitagliano, Maria Romano, Giarita Ferraro, Luciana Esposito, Daniela Caruso, Romualdo Troisi, Areej Abuhammad, Irwin Selvam, Miguel Moreira, Rita Berisio, Flavia Squeglia, Nicole Balasco, Mussa Quareshy, Davide Esposito, Giovanni Smaldone, Annica Saaret, Ida Autiero
Publikováno v:
Acta Crystallogr F Struct Biol Commun
Domain swapping is a widespread oligomerization process that is observed in a large variety of protein families. In the large superfamily of substrate-binding proteins, non-monomeric members have rarely been reported. The arginine-binding protein fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13edf3c6fd362d16e1b79cfddb045dc5