Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Irwin Scher"'
Autor:
Kenneth W. Sell, David H. Sachs, William E. Paul, Irwin Scher, Allan H Smith, Susan O. Sharrow, Aftab Ahmed
Publikováno v:
The Journal of Experimental Medicine
CBA/N mice and F1 male mice, which are hemizygous for the CBA/N X chromosome, have an immune defect which is associated with the absence (deficiency) of a subpopulation of mature or late developing B lymphocytes. This characteristic was utilized to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c540213b5fcfa171a5abbc24b42e9c7f
https://doi.org/10.1084/jem.145.1.101
https://doi.org/10.1084/jem.145.1.101
Publikováno v:
The Journal of Immunology. 123:477-486
The primary thymus-dependent IgG anti-sheep red blood cell (SRBC) response of (CBA/N × DBA/2)F1 male mice was An interesting difference in the environments of (CBA/N × DBA/2)F1 vs (DBA/2 × CBA/N)F1 male mice was demonstrated by reconstituting thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8afcfc43daa30d21933b7a1a280c8f20
https://doi.org/10.4049/jimmunol.123.1.477
https://doi.org/10.4049/jimmunol.123.1.477
Autor:
Donald E. Mosier, E. A. Goldings, William E. Paul, Irwin Scher, N. M. Zaldivar, James J. Mond
Publikováno v:
Journal of Infectious Diseases. 136:S14-S19
The ontogeny of immune responsiveness, as assayed by antibody formation in vitro, of mouse spleen lymphocytes to thymus-independent antigens is reviewed. Responsiveness to trinitrophenyl (TNP)-lipopolysaccharide and TNP-Brucella abortus appear soon a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff07810238ef5466e15057e0949d6005
https://doi.org/10.1093/infdis/136.supplement.s14
https://doi.org/10.1093/infdis/136.supplement.s14
Publikováno v:
The Journal of Experimental Medicine
CBA/N mice have an X-linked defect in B-lymphocyte function characterized by a failure to respond to certain thymus-independent antigens. When studied by rapid flow microfluorometry, adult CBA/N splenic B lymphocytes labeled with either fluorescein-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c5c0501dcd421056272200b3473038
https://doi.org/10.1084/jem.144.2.507
https://doi.org/10.1084/jem.144.2.507
Publikováno v:
The Journal of Experimental Medicine
The density of total Ig and of IgM, IgG1, IgG2, and IgA on the surface of adult murine splenic B lymphocytes was measured using the technique of rapid flow microfluorometry. In addition, the density of total surface Ig and of IgM on B lymphocytes der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec225d71486b7670eb3789c5c92b0b4
https://doi.org/10.1084/jem.144.2.494
https://doi.org/10.1084/jem.144.2.494
Publikováno v:
The Journal of Experimental Medicine
Heterologous anti-delta-chain antibodies have an adjuvant effect on specific in vivo humoral immune responses to simultaneously, or subsequently, injected antigens in the rat and rhesus monkey. We have used a hybridoma-secreted antibody that binds mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea84a28f4f74505964c8eaa5024bab84
http://europepmc.org/articles/PMC2185918
http://europepmc.org/articles/PMC2185918
Publikováno v:
Infection and Immunity. 25:513-520
The role of macrophages in the innate immunity of (CBA/N female X DBA/2N male)F1 female mice to Salmonella typhimurium was assessed with silica, an agent which has been reported to selectively inactivate macrophages. Silica, administered intravenousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d77deeb5ccdf00979608ba50054ad54
https://doi.org/10.1128/iai.25.2.513-520.1979
https://doi.org/10.1128/iai.25.2.513-520.1979
Publikováno v:
Cellular Immunology. 30:122-134
The minor lymphocyte stimulating (Mls) locus codes for lymphocyte activating determinants (LADs) on murine B lymphocytes, but not T lymphocytes. This observation was strengthened by a series of techniques which allow deletion and addition of T and B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25fcd560ead3c57dfa4508badb010396
https://doi.org/10.1016/0008-8749(77)90053-3
https://doi.org/10.1016/0008-8749(77)90053-3
Publikováno v:
The Journal of Immunology. 116:454-461
B cells from C3H/HeJ mice fail to respond to an endotoxin (LPS K235) which is mitogenic for normal mice including the closely related C3H/HeN strain. The cellular basis for this unresponsive state has been investigated. The C3H/HeJ mice have normal n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::728c2ad2fb0bbf6bc6fd9d3b416c78f3
https://doi.org/10.4049/jimmunol.116.2.454
https://doi.org/10.4049/jimmunol.116.2.454
Publikováno v:
The Journal of Experimental Medicine
Mouse spleen cells can be stimulated to proliferate in vitro by purified anti-mu or anti-gamma,kappa antibodies. These responses can be obtained in cell populations bearing membrane immunoglobulin (Ig), purified by the fluorescence activated cell sor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965c689774778d57d7a997e47433aee3
https://doi.org/10.1084/jem.148.6.1628
https://doi.org/10.1084/jem.148.6.1628