Zobrazeno 1 - 10
of 473
pro vyhledávání: '"Irwin Lucki"'
Publikováno v:
Neurobiology of Stress, Vol 11, Iss , Pp - (2019)
Alterations to the mesolimbic dopamine (DA) system are thought to underlie dysfunctional reward processing in stress-related psychiatric disorders. Using in vivio microdialysis in awake freely moving mice, we assessed the effects of stress on the mot
Externí odkaz:
https://doaj.org/article/b99db393849543e19ce10a9d0e44d261
Publikováno v:
Neurobiology of Stress, Vol 3, Iss C, Pp 34-42 (2016)
Both genetic background and pre-existing stress play critical roles in the effects of antidepressant drugs. The current studies showed this principal by demonstrating that exposure to the stress hormone corticosterone (CORT) allowed behavioral and ne
Externí odkaz:
https://doaj.org/article/d6fe8e1ed0e042b78ec826a41d109889
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
Clinical and preclinical evidence implicates hyperexcitability of the lateral habenula (LHb) in the development of psychiatric disorders including major depressive disorder (MDD). This discrete epithalamic nucleus acts as a relay hub linking forebrai
Externí odkaz:
https://doaj.org/article/54909aab23e64410ac6520989e5ad916
Autor:
Ryan D. Shepard, Ludovic D. Langlois, Caroline A. Browne, Aylar Berenji, Irwin Lucki, Fereshteh S. Nugent
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
Mounting evidence suggests that the long-term effects of adverse early life stressors on vulnerability to drug addiction and mood disorders are related to dysfunction of brain monoaminergic signaling in reward circuits. Recently, there has been a gro
Externí odkaz:
https://doaj.org/article/340e7cbabfb24a77b4247cee4a3e6c84
Autor:
Steven E. Arnold, Irwin Lucki, Bethany R. Brookshire, Gregory C. Carlson, Caroline A. Browne, Hala Kazi, Sookhee Bang, Bo-Ran Choi, Yong Chen, Mary F. McMullen, Sangwon F. Kim
Publikováno v:
Neurobiology of Disease, Vol 67, Iss , Pp 79-87 (2014)
Insulin resistance and other features of the metabolic syndrome are increasingly recognized for their effects on cognitive health. To ascertain mechanisms by which this occurs, we fed mice a very high fat diet (60% kcal by fat) for 17 days or a moder
Externí odkaz:
https://doaj.org/article/0f2c69c70c3044f080016390788f6f49
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 382:256-265
Publikováno v:
Psychopharmacology. 239:2309-2316
Publikováno v:
Neuroscience & Biobehavioral Reviews. 127:365-376
Mild traumatic brain injury (mTBI) increases the risk of posttraumatic stress disorder (PTSD) in military populations. Utilizing translationally relevant animal models is imperative for establishing a platform to delineate neurobehavioral deficits co
Publikováno v:
Neuropharmacology. 221
The ketamine metabolite (2R,6R)-hydroxynorketamine, or (2R,6R)-HNK, was recently reported to evoke antinociception in response to a noxious thermal stimulus in healthy mice and reverse mechanical hypersensitivity in a murine model of neuropathic pain
Publikováno v:
The FASEB Journal. 36