Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Irwin KE"'
Autor:
Damien Meng-Kiat Leow, Irwin Kee-Mun Cheah, Lucrecia Chen, Yang-Kai Ng, Crystal Jing-Jing Yeo, Barry Halliwell, Wei-Yi Ong
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 693 (2024)
Cell death involving oxidative stress and mitochondrial dysfunction is a major cause of dopaminergic neuronal loss in the substantia nigra (SN) of Parkinson’s disease patients. Ergothioneine (ET), a natural dietary compound, has been shown to have
Externí odkaz:
https://doaj.org/article/4e01849889b64fed887664b880bec3b1
Autor:
Damien Meng-Kiat Leow, Irwin Kee-Mun Cheah, Zachary Wei-Jie Fong, Barry Halliwell, Wei-Yi Ong
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5498 (2023)
Recent findings have suggested that the natural compound ergothioneine (ET), which is synthesised by certain fungi and bacteria, has considerable cytoprotective potential. We previously demonstrated the anti-inflammatory effects of ET on 7-ketocholes
Externí odkaz:
https://doaj.org/article/58c85e421bd6436c86cefb738f4f0cdb
Autor:
Hwee-Woon Lim, Woei-Yuh Saw, Lei Feng, Yuan-Kun Lee, Ratha Mahendran, Irwin Kee-Mun Cheah, Iris Rawtaer, Alan Prem Kumar, Ee-Heok Kua, Rathi Mahendran, Ene-Choo Tan
Publikováno v:
Data in Brief, Vol 18, Iss , Pp 902-912 (2018)
It has been reported that relaxation techniques can improve physical health and cognitive function. A number of studies involving different types of relaxation practices showed changes in expression of genes. We investigated the gene expression patte
Externí odkaz:
https://doaj.org/article/b029837db2964ee887872eb360e17d4a
Publikováno v:
Journal of Geriatric Physical Therapy; 2005, Vol. 28 Issue 3, p93-101, 9p
Autor:
Jasmine Tan, F. H. Maurine Tsakok, Elisabeth K. Ow, Bernard Lanskey, Kian Siong Darius Lim, Lee Gan Goh, Chay-Hoon Tan, Irwin Kee-Mun Cheah, Anis Larbi, Roger Foo, Marie Loh, Caroline Kai Yun Wong, John Suckling, Jialiang Li, Rathi Mahendran, Ee-Heok Kua, Lei Feng
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Introduction: This study is a parallel-arm randomized controlled trial evaluating choral singing’s efficacy and underlying mechanisms in preventing cognitive decline in at-risk older participants.Methods: Three-hundred and sixty community-dwelling,
Externí odkaz:
https://doaj.org/article/6020848c875d44b9badaaea9a5b4dd88
Autor:
Hanan DM; Simmons University, College of Natural, Behavioral, and Health Sciences, 300 The Fenway, Boston, MA 02115, United States of America. Electronic address: diana.hanan2@simmons.edu., Lyons KS; William F. Connell School of Nursing, Boston College, Maloney Hall 231, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, United States of America. Electronic address: lyonskw@bc.edu., Mahoney EK; William F. Connell School of Nursing, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, United States of America. Electronic address: ellen.mahoney@bc.edu., Irwin KE; Harvard Medical School, Collaborative Care and Community Engagement Program, Massachusetts General Cancer Center, Yawkey 10B, 55 Fruit Street, Boston, MA 02114, United States of America. Electronic address: kirwin1@partners.org., Flanagan JM; William F. Connell School of Nursing, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, United States of America. Electronic address: flanagjg@bc.edu.
Publikováno v:
Archives of psychiatric nursing [Arch Psychiatr Nurs] 2024 Aug; Vol. 51, pp. 25-29. Date of Electronic Publication: 2024 May 11.
Autor:
Irwin KE; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA.; Department of Neuroscience, Johns Hopkins Medicine, Baltimore, MD, USA., Jasin P; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA., Braunstein KE; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA., Sinha IR; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA.; Department of Neuroscience, Johns Hopkins Medicine, Baltimore, MD, USA., Garret MA; Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA., Bowden KD; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA.; Department of Neuroscience, Johns Hopkins Medicine, Baltimore, MD, USA., Chang K; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA.; Department and Graduate Institute of Pathology, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan., Troncoso JC; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA.; Department of Neurology, Johns Hopkins Medicine, Baltimore, MD, USA., Moghekar A; Department of Neurology, Johns Hopkins Medicine, Baltimore, MD, USA., Oh ES; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA.; Department of Medicine, Johns Hopkins Medicine, Baltimore, MD, USA.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins Medicine, Baltimore, MD, USA., Raitcheva D; Biogen, Cambridge, MA, USA., Bartlett D; Biogen, Cambridge, MA, USA., Miller T; Department of Neurology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Berry JD; Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA., Traynor BJ; Department of Neurology, Johns Hopkins Medicine, Baltimore, MD, USA.; Neuromuscular Diseases Research Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.; National Institute of Neurological Disorders, National Institutes of Health, Bethesda, MD, USA.; RNA Therapeutics Laboratory, Therapeutics Development Branch, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Ling JP; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA., Wong PC; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA. wong@jhmi.edu.; Department of Neuroscience, Johns Hopkins Medicine, Baltimore, MD, USA. wong@jhmi.edu.
Publikováno v:
Nature medicine [Nat Med] 2024 May; Vol. 30 (5), pp. 1504.
Autor:
Sinha IR; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Sandal PS; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Burns GD; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Mallika AP; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Irwin KE; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Cruz ALF; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Wang V; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA., Rodríguez JL; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Wong PC; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Ling JP; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2024 Mar 30. Date of Electronic Publication: 2024 Mar 30.
Autor:
Irwin KE; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA.; Department of Neuroscience, Johns Hopkins Medicine, Baltimore, MD, USA., Jasin P; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA., Braunstein KE; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA., Sinha IR; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA.; Department of Neuroscience, Johns Hopkins Medicine, Baltimore, MD, USA., Garret MA; Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA., Bowden KD; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA.; Department of Neuroscience, Johns Hopkins Medicine, Baltimore, MD, USA., Chang K; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA.; Department and Graduate Institute of Pathology, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan., Troncoso JC; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA.; Department of Neurology, Johns Hopkins Medicine, Baltimore, MD, USA., Moghekar A; Department of Neurology, Johns Hopkins Medicine, Baltimore, MD, USA., Oh ES; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA.; Department of Medicine, Johns Hopkins Medicine, Baltimore, MD, USA.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins Medicine, Baltimore, MD, USA., Raitcheva D; Biogen, Cambridge, MA, USA., Bartlett D; Biogen, Cambridge, MA, USA., Miller T; Department of Neurology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Berry JD; Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA., Traynor BJ; Department of Neurology, Johns Hopkins Medicine, Baltimore, MD, USA.; Neuromuscular Diseases Research Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.; National Institute of Neurological Disorders, National Institutes of Health, Bethesda, MD, USA.; RNA Therapeutics Laboratory, Therapeutics Development Branch, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Ling JP; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA., Wong PC; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, USA. wong@jhmi.edu.; Department of Neuroscience, Johns Hopkins Medicine, Baltimore, MD, USA. wong@jhmi.edu.
Publikováno v:
Nature medicine [Nat Med] 2024 Feb; Vol. 30 (2), pp. 382-393. Date of Electronic Publication: 2024 Jan 26.
Autor:
Irwin KE; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, 21205, USA.; Department of Neuroscience, Johns Hopkins Medicine, Baltimore, MD, 21205, USA., Sheth U; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Jacksonville, FL, 32224, USA., Wong PC; Department of Pathology, Johns Hopkins Medicine, Baltimore, MD, 21205, USA. Wong@jhmi.edu.; Department of Neuroscience, Johns Hopkins Medicine, Baltimore, MD, 21205, USA. Wong@jhmi.edu., Gendron TF; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA. Gendron.Tania@mayo.edu.; Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Jacksonville, FL, 32224, USA. Gendron.Tania@mayo.edu.
Publikováno v:
Molecular neurodegeneration [Mol Neurodegener] 2024 Jan 24; Vol. 19 (1), pp. 9. Date of Electronic Publication: 2024 Jan 24.