Zobrazeno 1 - 10
of 8 393
pro vyhledávání: '"Irving L"'
Autor:
Satu Strausz, Erik Abner, Grace Blacker, Sarah Galloway, Paige Hansen, Qingying Feng, Brandon T. Lee, Samuel E. Jones, Hele Haapaniemi, Sten Raak, George Ronald Nahass, Erin Sanders, FinnGen, Estonian Genome Centre, Estonian Biobank Research Team, Pilleriin Soodla, Urmo Võsa, Tõnu Esko, Nasa Sinnott-Armstrong, Irving L. Weissman, Mark Daly, Tuomas Aivelo, Michal Caspi Tal, Hanna M. Ollila
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Lyme disease is a tick-borne disease caused by bacteria of the genus Borrelia. The host factors that modulate susceptibility for Lyme disease have remained mostly unknown. Using epidemiological and genetic data from FinnGen and Estonian Biob
Externí odkaz:
https://doaj.org/article/6ff1c773b86b466eacdd4659aaa166eb
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102674- (2023)
Summary: Prospective isolation of defined cell types is critical for the functional study of stem cells, especially in primary human tissues. Here, we present a protocol for purifying 10 transcriptomically and functionally distinct neural stem and pr
Externí odkaz:
https://doaj.org/article/fcc200bd5513479c9874a52abfb3d13d
Autor:
Raymond J. Strobel, Adishesh K. Narahari, Evan P. Rotar, Andrew M. Young, Jeffrey Vergales, J. Hunter Mehaffey, Nicholas R. Teman, John A. Kern, Leora T. Yarboro, Irving L. Kron, Michael R. Nelson, Mark Roeser
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 17 (2023)
Background Adults undergoing heart surgery are particularly vulnerable to respiratory complications, including COVID‐19. Immunization can significantly reduce this risk; however, the effect of cardiopulmonary bypass (CPB) on immunization status is
Externí odkaz:
https://doaj.org/article/20e4b10b914c4770abd56f8b2a01c285
Autor:
Irving L. M. H. Aye, Sungsam Gong, Giulia Avellino, Roberta Barbagallo, Francesca Gaccioli, Benjamin J. Jenkins, Albert Koulman, Andrew J. Murray, D. Stephen Charnock-Jones, Gordon C. S. Smith
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Sex-dependent metabolism of spermine alter trophoblast gene expression through acetyl-coA biosynthesis and histone acetylation, indicating that escape of spermine synthase from X-linked inactivation partially contributes to placental sex differences.
Externí odkaz:
https://doaj.org/article/cdce78ca2527441a93b56d28ce2132f9
Autor:
Aimee Zhang, Radhika Rastogi, Katherine M. Marsh, Boris Yang, Di Wu, Irving L. Kron, Zequan Yang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundFollowing acute myocardial infarction (MI), irreversible damage to the myocardium can only be reduced by shortening the duration between symptom onset and revascularization. While systemic hypothermia has shown promising results in slowing
Externí odkaz:
https://doaj.org/article/d756af18fc1946929e95b572293ec459
Autor:
Jane L. Tarry-Adkins, India G. Robinson, Rebecca M. Reynolds, Irving L. M. H. Aye, D. Stephen Charnock-Jones, Benjamin Jenkins, Albert Koulmann, Susan E. Ozanne, Catherine E. Aiken
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Metformin is increasingly prescribed in pregnancy, with beneficial maternal effects. However, it is not known how metformin-treatment impacts metabolism and energy production in the developing feto-placental unit. We assessed the human placental resp
Externí odkaz:
https://doaj.org/article/adf9536457374c3fb90f435c466ac81a
Autor:
Chiara Anselmi, Federico Caicci, Tommaso Bocci, Matteo Guidetti, Alberto Priori, Veronica Giusti, Tom Levy, Tal Raveh, Ayelet Voskoboynik, Irving L. Weissman, Lucia Manni
Publikováno v:
Cells, Vol 12, Iss 7, p 1041 (2023)
Human neuronal loss occurs through different cellular mechanisms, mainly studied in vitro. Here, we characterized neuronal death in B. schlosseri, a marine colonial tunicate that shares substantial genomic homology with mammals and has a life history
Externí odkaz:
https://doaj.org/article/3a3eb11a34e842b78aced2754c51ae47
Publikováno v:
International Journal of COPD, Vol Volume 15, Pp 3251-3259 (2020)
Peter Wallbridge,1,2 Mark Hew,1,3,4 Selina M Parry,5 Louis Irving,1,2 Daniel Steinfort1,2 1Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC, Australia; 2Department of Respiratory and Sleep Medicine, Royal
Externí odkaz:
https://doaj.org/article/a41aebcf20044fe6a4d7668b444c4982
Autor:
Dominique M. O. Higgins, Maisel Caliva, Mark Schroeder, Brett Carlson, Pavan S. Upadhyayula, Brian D. Milligan, Samuel H. Cheshier, Irving L. Weissman, Jann N. Sarkaria, Fredric B. Meyer, John R. Henley
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults, with a median survival of approximately 15 months. Semaphorin 3A (Sema3A), known for its axon guidance and antiangiogenic properties, has been implica
Externí odkaz:
https://doaj.org/article/1d0c9d1a12074eb5801bde5c8e5fa9b3
Autor:
Joseph M. McCune, Irving L. Weissman
Publikováno v:
Stem Cell Reports, Vol 13, Iss 5, Pp 777-786 (2019)
Some have argued that human fetal tissue research is unnecessary and/or immoral. Recently, the Trump administration has taken the drastic––and we believe misguided––step to effectively ban government-funded research on fetal tissue altogether
Externí odkaz:
https://doaj.org/article/fbe151ea49d84e60be71a8ea14ab0cfd