Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Irving Barrera"'
Autor:
Hyun Jae Lee, Marcela L. Moreira, Shihan Li, Takahiro Asatsuma, Cameron G. Williams, Oliver P. Skinner, Saba Asad, Michael Bramhall, Zhe Jiang, Zihan Liu, Ashlyn S. Kerr, Jessica A. Engel, Megan S. F. Soon, Jasmin Straube, Irving Barrera, Evan Murray, Fei Chen, Jason Nideffer, Prasanna Jagannathan, Ashraful Haque
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Children in malaria-endemic regions can experience repeated Plasmodium infections over short periods of time. Effects of re-infection on multiple co-existing CD4+ T cell subsets remain unresolved. Here, we examine antigen-experienced CD4+ T
Externí odkaz:
https://doaj.org/article/4d3cc96140c047edad0a1f3a0d29e9e7
Autor:
Cameron G. Williams, Marcela L. Moreira, Takahiro Asatsuma, Hyun Jae Lee, Shihan Li, Irving Barrera, Evan Murray, Megan S.F. Soon, Jessica A. Engel, David S. Khoury, Shirley Le, Brooke J. Wanrooy, Dominick Schienstock, Yannick O. Alexandre, Oliver P. Skinner, Rainon Joseph, Lynette Beattie, Scott N. Mueller, Fei Chen, Ashraful Haque
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114317- (2024)
Summary: Naive CD4+ T cells must differentiate in order to orchestrate immunity to Plasmodium, yet understanding of their emerging phenotypes, clonality, spatial distributions, and cellular interactions remains incomplete. Here, we observe that splen
Externí odkaz:
https://doaj.org/article/4373d17359cc4902a9813dc482a0fa59
Autor:
Hyun Jae Lee, Marcela L. Moreira, Shihan Li, Cameron G. Williams, Oliver P. Skinner, Saba Asad, Takahiro Asatsuma, Michael Bramhall, Zhe Jiang, Jessica A. Engel, Megan S. F. Soon, Jasmin Straube, Irving Barrera, Evan Murray, Fei Chen, Jason Nideffer, Prasanna Jagannathan, Ashraful Haque
Children in malaria-endemic regions can experience multiplePlasmodiuminfections over a short period of time, within vitroCD4+T cell recall responses becoming more regulatory with increasing age and exposure. This suggests that repeated infection qual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b3324488591cc43967f206bc5452275
https://doi.org/10.1101/2023.03.02.530907
https://doi.org/10.1101/2023.03.02.530907
Autor:
Cameron G. Williams, Marcela L. Moreira, Takahiro Asatsuma, Oliver P. Skinner, Hyun Jae Lee, Shihan Li, Irving Barrera, Evan Murray, Megan S. F. Soon, Jessica A. Engel, David S. Khoury, Saba Asad, Thiago Mass Steiner, Rainon Joseph, Yannick Alexandre, Scott N. Mueller, Fei Chen, Ashraful Haque
CD4+T cells orchestrate adaptive immunity to circulating malaria parasites; yet cellular interactions and molecular mechanisms controlling Th1 and Tfh differentiation in the spleen remain to be fully definedin vivo. Here, using a murine model of CD4-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20eb8a49595b6860a88ba3666cecec27
https://doi.org/10.1101/2023.02.23.529309
https://doi.org/10.1101/2023.02.23.529309
Autor:
Yiping Wang, Joy Linyue Fan, Johannes C. Melms, Amit Dipak Amin, Yohanna Georgis, Irving Barrera, Patricia Ho, Somnath Tagore, Gabriel Abril-Rodríguez, Siyu He, Yinuo Jin, Jana Biermann, Matan Hofree, Lindsay Caprio, Simon Berhe, Shaheer A. Khan, Brian S. Henick, Antoni Ribas, Evan Z. Macosko, Fei Chen, Alison M. Taylor, Gary K. Schwartz, Richard D. Carvajal, Elham Azizi, Benjamin Izar
Publikováno v:
Nature genetics, vol 55, iss 1
Nat Genet
Nat Genet
Single-cell genomics enables dissection of tumor heterogeneity and molecular underpinnings of drug response at an unprecedented resolution1-11. However, broad clinical application of these methods remains challenging, due to several practical and pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9dae4871dcfe3694de898e5b309ea7
https://escholarship.org/uc/item/1sc8z1wh
https://escholarship.org/uc/item/1sc8z1wh
Autor:
Bryan Iorgulescu, Sophia Liu, Shuqiang Li, Mehdi Borji, Irving Barrera-Lopez, Vignesh Shanmugam, Haoxiang Lyu, Julia Morriss, Zoe Garcia, Evan Murray, David Reardon, Charles Yoon, David Braun, Ken Livak, Catherine Wu, Fei Chen
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Sherry Jingjing Wu, Elaine Sevier, Giuseppe-Antonio Saldi, Sabrina Yu, Lydia Abbott, Da Hae Choi, Mia Sherer, Yanjie Qiu, Ashwini Shinde, Daniella Rizzo, Qing Xu, Irving Barrera, Vipin Kumar, Giovanni Marrero, Alvar Prönneke, Shuhan Huang, Bernardo Rudy, David A. Stafford, Evan Macosko, Fei Chen, Gord Fishell
SUMMARYThe cardinal interneuron classes are a useful simplification of cortical interneuron diversity, but such broad subgroupings glosses over the molecular, morphological, and circuit specificity of interneuron subtypes, most notably among the soma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25cc5cfea8356b82d9084bd5bfdbf22e
https://doi.org/10.1101/2022.09.29.510081
https://doi.org/10.1101/2022.09.29.510081
Autor:
Somnath Tagore, Lindsay Caprio, Amit Dipak Amin, Irving Barrera, Johannes Melms, Karan Luthria, Yiping Wang, Yohanna Georgis, Abhi Jaiswal, Galina G. Lagos, Zachary Walsh, Parin Shah, Jana Biermann, Neha Sheikh, Priyanka Ramaradj, Niroshana Anandasabapathy, Hanina Hibshoosh, Gary Schwartz, Brian Henick, Alison Taylor, Fei Chen, Benjamin Izar
Publikováno v:
Cancer Research. 83:3517-3517
Non-small cell lung cancer (NSCLC) accounts for nearly half of all newly diagnosed patients with brain metastasis (BM), followed by melanoma and breast carcinomas. The presence of BM is associated with reduced response to several modern cancer therap
Autor:
Robert Stickels, Evan Murray, Jamie L Marshall, Karol Balderrama, Irving Barrera, Evan Macosko, Fei Chen
This is a protocol detailing the steps necessary to generate libraries using previously manufactured Slide-seq arrays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e54aa213d952fb2dcb06f283d1f67024
https://doi.org/10.17504/protocols.io.bxijpkcn
https://doi.org/10.17504/protocols.io.bxijpkcn
Autor:
Jana Biermann, Johannes C. Melms, Amit Dipak Amin, Yiping Wang, Lindsay A. Caprio, Alcida Karz, Somnath Tagore, Irving Barrera, Miguel A. Ibarra-Arellano, Massimo Andreatta, Benjamin T. Fullerton, Kristjan H. Gretarsson, Varun Sahu, Vaibhav S. Mangipudy, Trang T.T. Nguyen, Ajay Nair, Meri Rogava, Patricia Ho, Peter D. Koch, Matei Banu, Nelson Humala, Aayushi Mahajan, Zachary H. Walsh, Shivem B. Shah, Daniel H. Vaccaro, Blake Caldwell, Michael Mu, Florian Wünnemann, Margot Chazotte, Simon Berhe, Adrienne M. Luoma, Joseph Driver, Matthew Ingham, Shaheer A. Khan, Suthee Rapisuwon, Craig L. Slingluff, Thomas Eigentler, Martin Röcken, Richard Carvajal, Michael B. Atkins, Michael A. Davies, Albert Agustinus, Samuel F. Bakhoum, Elham Azizi, Markus Siegelin, Chao Lu, Santiago J. Carmona, Hanina Hibshoosh, Antoni Ribas, Peter Canoll, Jeffrey N. Bruce, Wenya Linda Bi, Praveen Agrawal, Denis Schapiro, Eva Hernando, Evan Z. Macosko, Fei Chen, Gary K. Schwartz, Benjamin Izar
Publikováno v:
Cell
Melanoma brain metastasis (MBM) frequently occurs in patients with advanced melanoma, yet our understanding of the underlying salient biology is rudimentary. Here, we performed single-cell/nucleus RNA-seq in 22 treatment-naïve MBM and 10 extracrania