Zobrazeno 1 - 10 of 53 pro vyhledávání: '"Irvine G. McQuarrie"'
1
INTRA-AXONAL MYOSIN AND ACTIN IN NERVE REGENERATION
Autor: Irvine G. McQuarrie, Linda M. Lund
Publikováno v: Neurosurgery. 65:A93-A96
A focused review of sciatic nerve regeneration in the rat model, based on research conducted by the authors, is presented. We examine structural proteins carried distally in the axon by energy-requiring motor enzymes, using protein chemistry and mole
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ccfae0cc22d44b737f3334df7d557b
https://doi.org/10.1227/01.neu.0000338593.76635.32
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2
Calcium/calmodulin-dependent protein kinase II? isoform is expressed in motor neurons during axon outgrowth and is part of slow axonal transport
Autor: Irvine G. McQuarrie, Linda M. Lund
Publikováno v: Journal of Neuroscience Research. 67:720-728
Previously, we identified calcium/calmodulin-dependent protein kinase IIβ (CaMKIIβ) mRNA in spinal motor neurons with 372 bp inserted in what corresponds to the “association” domain of the protein. This was interesting because known additions a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6dfc922ebce4e07549e6574f4bfe9f
https://doi.org/10.1002/jnr.10162
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3
Diagnostic Status and Treatment Recommendations for Persian Gulf War Veterans with Multiple Nonspecific Symptoms
Autor: Megan G. Murray, Charles L. Mendenhall, Linda M. Lund, Irvine G. McQuarrie, Dewleen G. Baker, Boris A. Dashevsky
Publikováno v: Military Medicine. 166:972-981
Background Unexplained symptoms have frequently been observed in deployed Persian Gulf War veterans (GWVs). Using factor analysis, the Centers for Disease Control and Prevention (CDC) has established criteria for Gulf War illness (GWI). We report her
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1093823e47efd58a3cfad6ed86d360f
https://doi.org/10.1093/milmed/166.11.972
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5
Calcium/calmodulin-dependent protein kinase II expression in motor neurons: Effect of axotomy
Autor: Irvine G. McQuarrie, Linda M. Lund
Publikováno v: Journal of Neurobiology. 33:796-810
Although Ca2+/calmodulin-dependent (CaM) protein kinase II isoforms are present in the nervous system in high amounts, many aspects of in vivo expression, localization, and function remain unexplored. During development, CaM kinase IIα and IIβ are
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae82e92730a62a8443a76bc62528d278
https://doi.org/10.1002/(sici)1097-4695(19971120)33:6<796::aid-neu7>3.0.co
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6
Axonal regrowth upregulates ?-actin and Jun D mRNA expression
Autor: Irvine G. McQuarrie, Linda M. Lund
Publikováno v: Journal of Neurobiology. 31:476-486
When quiescent cells are perturbed, mRNAs encoding proteins that regulate gene transcription and the cell cycle are expressed at higher levels. Jun and Fos are examples of proteins that mediate mitogenic signals and influence differentiation. In neur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::93f69a705090831ff8f0486d9a9c9a17
https://doi.org/10.1002/(sici)1097-4695(199612)31:4<476::aid-neu7>3.0.co
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7
Assembly of microfilaments and microtubules from axonally transported actin and tubulin after axotomy
Autor: Irvine G. McQuarrie, J.M. Jacob
Publikováno v: Journal of Neuroscience Research. 43:412-419
The slow component (SC) of axonal transport conveys structural proteins, regulatory proteins, and glycolytic enzymes toward the axon tip at 1-6 mm/day. Following axon interruption (axotomy), the rate of outgrowth corresponds to the rate of SCb-the fa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e76c1bf564f55bcf73867d01397082d
https://doi.org/10.1002/(sici)1097-4547(19960215)43:4<412::aid-jnr3>3.0.co
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8
Retardation of fast axonal transport in wobbler mice
Autor: Kozo Kurahashi, Irvine G. McQuarrie, Jane M. Jacob, Hiroshi Mitsumoto
Publikováno v: Muscle & Nerve. 16:542-547
To investigate axonal function in a model of early motor neuron disease, we examined fast and slow components of anterograde axonal transport in the less-affected hindlimb motor neurons of wobbler mice. To study the fast component (FC), we injected t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3887e5980b0b85bc75d935f1155ca9be
https://doi.org/10.1002/mus.880160517
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9
Increased slow transport in axons of regenerating newt limbs after a nerve conditioning lesion
Autor: C. Eberhardt Maier, Irvine G. McQuarrie
Publikováno v: Developmental Biology. 140:172-181
We have previously shown that a nerve conditioning lesion (CL) made 2 weeks prior to amputation results in an earlier onset of limb regeneration in newts. Studies in fish and mammals demonstrate that when a CL precedes a nerve testing lesion, slow co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e5d5f8fc4c8f30e41e85c521f718b0
https://doi.org/10.1016/0012-1606(90)90064-p
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10
Axonal isoforms of myosin-I
Autor: Linda M. Lund, Victor M. Machado, Irvine G. McQuarrie
Publikováno v: Biochemical and biophysical research communications. 330(3)
We have examined spinal motor neurons in Sprague–Dawley rats to further characterize a mechanoenzyme, myosin-Iγ (myr4), which is found in high concentration during axon tract formation in neonates. We raised an antibody to myr4 and made riboprobes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de965237aa8563755982c42b28f86a14
https://pubmed.ncbi.nlm.nih.gov/15809075
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