Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Irvin Jose"'
Autor:
Zhipeng Cao, Ingrid J. Burvenich, Kening Zhao, Clare Senko, Jason Glab, Renee Fogliaro, Zhanqi Liu, Irvin Jose, Hamsa Puthalakath, Nick J. Hoogenraad, Laura D. Osellame, Andrew M. Scott
Publikováno v:
Cancers, Vol 14, Iss 22, p 5533 (2022)
Background: Developing therapies for cancer cachexia has not been successful to date, in part due to the challenges of achieving robust quantitative measures as a readout of patient treatment. Hence, identifying biomarkers to assess the outcomes of t
Externí odkaz:
https://doaj.org/article/2fd640a0d7d04510b8fc849a8913b9c0
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4501 (2021)
Cancer cachexia is a common condition in many cancer patients, particularly those with advanced disease. Cancer cachexia patients are generally less tolerant to chemotherapies and radiotherapies, largely limiting their treatment options. While the se
Externí odkaz:
https://doaj.org/article/c7d26dc430194be8a79d9ed05f4b3131
Autor:
Zhipeng Cao, Ingrid J. Burvenich, Kening Zhao, Clare Senko, Jason Glab, Renee Fogliaro, Zhanqi Liu, Irvin Jose, Hamsa Puthalakath, Nick J. Hoogenraad, Laura D. Osellame, Andrew M. Scott
Publikováno v:
Cancers; Volume 14; Issue 22; Pages: 5533
Background: Developing therapies for cancer cachexia has not been successful to date, in part due to the challenges of achieving robust quantitative measures as a readout of patient treatment. Hence, identifying biomarkers to assess the outcomes of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6cc47e554d7b40cba89c466fe4fdd0d
Autor:
Irvin Jose, Ashley Mansell, Liana Mackiewicz, Boris Reljic, Richard S. Hotchkiss, Hamsa Puthalakath, Joseph Menassa, Christina Nedeva, Pierre Faou, Marc Pellegrini, Marcel Doerflinger
Publikováno v:
The FEBS Journal. 288:1809-1821
Sepsis remains to be a major contributor to mortality in ICUs, and immune suppression caused by immune cell apoptosis determines the overall patient survival. However, diagnosis of sepsis-induced lymphopenia remains problematic with no accurate progn
Autor:
Gabriella Brumatti, Marco J Herold, Hamsa Puthalakath, Jason Glab, James C. Paton, David J. Segal, Andrew J. Kueh, Irvin Jose, David C.S. Huang, Marcel Doerflinger, Christina Nedeva, George W Mbogo, Adrienne W. Paton
The endoplasmic reticulum (ER) stress response constitutes cellular reactions triggered by a wide variety of stimuli that disturb folding of proteins, often leading to apoptosis. ER stress-induced apoptotic cell death is thought to be an important co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b73ea6bce5a31fe8c1c126c01a5423
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4501, p 4501 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Cancer cachexia is a common condition in many cancer patients, particularly those with advanced disease. Cancer cachexia patients are generally less tolerant to chemotherapies and radiotherapies, largely limiting their treatment options. While the se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6016af728bf9772ecdc4f761367f06a5
Autor:
Marc Pellegrini, Christina Nedeva, Ann Lin, Jason Glab, Lorraine A. O'Reilly, Irvin Jose, Marcel Doerflinger, Cody C. Allison, Hamsa Puthalakath, Richard S. Hotchkiss
Publikováno v:
Scientific Reports
Sepsis-induced lymphopenia is a major cause of morbidities in intensive care units and in populations with chronic conditions such as renal failure, diabetes, HIV and alcohol abuse. Currently, other than supportive care and antibiotics, there are no