Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Irshad Sharafutdinov"'
Autor:
Irshad Sharafutdinov, Aileen Harrer, Mathias Müsken, Klemens Rottner, Heinrich Sticht, Christian Täger, Michael Naumann, Nicole Tegtmeyer, Steffen Backert
Publikováno v:
Cell Insight, Vol 3, Iss 3, Pp 100161- (2024)
Cell polarity is crucial for gastric mucosal barrier integrity and mainly regulated by polarity-regulating kinase partitioning-defective 1b (Par1b). During infection, the carcinogen Helicobacter pylori hijacks Par1b via the bacterial oncoprotein CagA
Externí odkaz:
https://doaj.org/article/7a045f07d3ac43e7910e40795eeae52e
Autor:
Irshad Sharafutdinov, Nicole Tegtmeyer, Manfred Rohde, Annelie Olofsson, Zia ur Rehman, Anna Arnqvist, Steffen Backert
Publikováno v:
Cells, Vol 13, Iss 3, p 224 (2024)
Fundamental functions of the intestinal epithelium include the digestion of food, absorption of nutrients, and its ability to act as the first barrier against intruding microbes. Campylobacter jejuni is a major zoonotic pathogen accounting for a subs
Externí odkaz:
https://doaj.org/article/d51819938d0349e7935bcd9fca4a5871
Publikováno v:
Cell Insight, Vol 1, Iss 3, Pp 100032- (2022)
Infection of the stomach by Helicobacter pylori is a major risk factor for the development of gastric cancer. Colonization of the gastric epithelium leads to the activation of multiple disease-related signaling pathways. Serine protease HtrA represen
Externí odkaz:
https://doaj.org/article/d165eb601e5c489c82f69836b4d06b43
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 323 (2023)
Infection with the main human food-borne pathogen Campylobacter jejuni causes campylobacteriosis that accounts for a substantial percentage of gastrointestinal infections. The disease usually manifests as diarrhea that lasts for up to two weeks. C. j
Externí odkaz:
https://doaj.org/article/eb0e2fec100746f8b4831bd57b46607b
Autor:
Irshad Sharafutdinov, Delara Soltan Esmaeili, Aileen Harrer, Nicole Tegtmeyer, Heinrich Sticht, Steffen Backert
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Campylobacter jejuni express the high temperature requirement protein A (HtrA), a secreted serine protease, which is implicated in virulence properties of the pathogen. Previous studies have shown that C. jejuni HtrA can cleave the epithelial transme
Externí odkaz:
https://doaj.org/article/4534afe0352646a6b5637f80ce568e70
Publikováno v:
Biomolecules, Vol 12, Iss 4, p 521 (2022)
Campylobacter jejuni represents an eminent zoonotic germ responsible for foodborne infections causing campylobacteriosis. In addition, infections with C. jejuni constitute a risk factor for the occurrence of inflammatory bowel disease (IBD). In the l
Externí odkaz:
https://doaj.org/article/29d2c34e4bbb433db10f83990511b321
Publikováno v:
Pathogens, Vol 11, Iss 1, p 3 (2021)
Cortactin is an actin-binding protein and actin-nucleation promoting factor regulating cytoskeletal rearrangements in eukaryotes. Helicobacter pylori is a gastric pathogen that exploits cortactin to its own benefit. During infection of gastric epithe
Externí odkaz:
https://doaj.org/article/118b2456a786447cba96722f65b3880f
Autor:
Anna Pavlova, Irshad Sharafutdinov
Publikováno v:
Microorganisms, Vol 8, Iss 9, p 1340 (2020)
Candida albicans is an opportunistic pathogenic fungus considered to be a common member of the human microflora. Similar to some other opportunistic microbes, C. albicans can invade and benefit from its host when the immune status of that host is wea
Externí odkaz:
https://doaj.org/article/20698f72b8a747c8a5885a2307b24af5
Publikováno v:
Molecular Microbiology. 118:623-636
Pathogenic bacteria possess a great potential of causing infectious diseases and represent a serious threat to human and animal health. Understanding the molecular basis of infection development can provide new valuable strategies for disease prevent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7103f87f95fafd431c41ea433b8ab3
https://doi.org/10.1111/mmi.15002
https://doi.org/10.1111/mmi.15002
Autor:
Nicole, Tegtmeyer, Irshad, Sharafutdinov, Aileen, Harrer, Delara, Soltan Esmaeili, Bodo, Linz, Steffen, Backert
Publikováno v:
Current topics in microbiology and immunology. 431
Campylobacter jejuni and Campylobacter coli can be frequently isolated from poultry and poultry-derived products, and in combination these two species cause a large portion of human bacterial gastroenteritis cases. While birds are typically colonized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e9e2800899f996bd65774f99900357e
https://pubmed.ncbi.nlm.nih.gov/33620652
https://pubmed.ncbi.nlm.nih.gov/33620652