Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Irshad Akbar"'
Autor:
Mohamed Reda Fazazi, Prenitha Mercy Ignatius Arokia Doss, Resel Pereira, Neva Fudge, Aryan Regmi, Charles Joly-Beauparlant, Irshad Akbar, Asmita Pradeep Yeola, Benoit Mailhot, Joanie Baillargeon, Philippe Grenier, Nicolas Bertrand, Steve Lacroix, Arnaud Droit, Craig S. Moore, Olga L. Rojas, Manu Rangachari
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract B cells and T cells collaborate in multiple sclerosis (MS) pathogenesis. IgH[MOG] mice possess a B cell repertoire skewed to recognize myelin oligodendrocyte glycoprotein (MOG). Here, we show that upon immunization with the T cell-obligate a
Externí odkaz:
https://doaj.org/article/03e8ecf578cd4ef3913cc229d2858241
Autor:
Amrita Ojha, Angika Bhasym, Sriparna Mukherjee, Gowtham K. Annarapu, Teena Bhakuni, Irshad Akbar, Tulika Seth, Naval K. Vikram, Sudhanshu Vrati, Anirban Basu, Sankar Bhattacharyya, Prasenjit Guchhait
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 332-347 (2019)
Background: Activated platelets release cytokines/proteins including CXCL4 (PF4), CCL5 and fibrinopeptides, which regulate infection of several pathogenic viruses such as HIV, H1N1 and HCV in human. Since platelet activation is the hallmark of Dengue
Externí odkaz:
https://doaj.org/article/2160851007864ce5b417ce20fe394447
Autor:
Prenitha Mercy Ignatius Arokia Doss, Muhammad Umair, Joanie Baillargeon, Reda Fazazi, Neva Fudge, Irshad Akbar, Asmita Pradeep Yeola, John B. Williams, Mickael Leclercq, Charles Joly-Beauparlant, Philippe Beauchemin, Gian Filipo Ruda, Melanie Alpaugh, Ana C. Anderson, Paul E. Brennan, Arnaud Droit, Hans Lassmann, Craig S. Moore, Manu Rangachari
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108833- (2021)
Summary: Sex differences in multiple sclerosis (MS) incidence and severity have long been recognized. However, the underlying cellular and molecular mechanisms for why male sex is associated with more aggressive disease remain poorly defined. Using a
Externí odkaz:
https://doaj.org/article/ebc3e40c4d1c4ab7996cfde36864bb5a
Autor:
Asmita Pradeep Yeola, Prenitha Mercy Ignatius Arokia Doss, Joanie Baillargeon, Irshad Akbar, Benoit Mailhot, Mohammad Balood, Sébastien Talbot, Ana Carrizosa Anderson, Steve Lacroix, Manu Rangachari
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
The T cell response to central nervous system (CNS) antigen in experimental autoimmune encephalomyelitis (EAE) permits one to model the immune aspects of multiple sclerosis. 1C6 transgenic mice on the non-obese diabetic (NOD) background possess a cla
Externí odkaz:
https://doaj.org/article/fd6386387f884591a25fb6871acc4ace
Autor:
Sriparna Mukherjee, Irshad Akbar, Reshma Bhagat, Bibhabasu Hazra, Arindam Bhattacharyya, Pankaj Seth, Dipanjan Roy, Anirban Basu
Publikováno v:
mSphere, Vol 4, Iss 5 (2019)
ABSTRACT RNA viruses are known to modulate host microRNA (miRNA) machinery for their own benefit. Japanese encephalitis virus (JEV), a neurotropic RNA virus, has been reported to manipulate several miRNAs in neurons or microglia. However, no report i
Externí odkaz:
https://doaj.org/article/4a0edbe967504d17ba117e0476c25242
Publikováno v:
Journal of biosciences. 45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f6cfaef7b2f13b790d37bdc0f326e32
https://pubmed.ncbi.nlm.nih.gov/32515359
https://pubmed.ncbi.nlm.nih.gov/32515359
Publikováno v:
Journal of Biosciences. 45
Japanese encephalitis virus, a neurotropic flavivirus, causes sporadic encephalitis with nearly 25% fatal case reports. JEV infects neural stem/progenitor cells (NSPCs) and decreases their proliferation. Statin, a commonly used class of cholesterol l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d70c2f6e0e9fa567aafccd56e8dc7d0
https://doi.org/10.1007/s12038-020-00052-3
https://doi.org/10.1007/s12038-020-00052-3
Autor:
Mohamed Reda Fazazi, Prenitha Mercy Ignatius Arokia Doss, Resel Pereira, Neva Fudge, Aryan Regmi, Irshad Akbar, Asmita Pradeep Yeola, Benoit Mailhot, Joanie Baillargeon, Philippe Grenier, Nicolas Bertrand, Steve Lacroix, Craig S. Moore, Olga L. Rojas, Manu Rangachari
Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system (CNS) that has traditionally been considered a T cell-mediated disease. However, accumulating evidence points to a crucial role for B cells in disease processes. IgH[MOG]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce0bdf8bd8e78f2d049675ed9dea5b6c
https://doi.org/10.1101/721696
https://doi.org/10.1101/721696
Autor:
Asmita, Pradeep Yeola, Irshad, Akbar, Joanie, Baillargeon, Prenitha, Mercy Ignatius Arokia Doss, Ville O, Paavilainen, Manu, Rangachari
Publikováno v:
Cytokine. 129
Effector CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8018a13b53b0f1863ace4cd0322a7448
https://pubmed.ncbi.nlm.nih.gov/32146280
https://pubmed.ncbi.nlm.nih.gov/32146280
Autor:
Philippe Beauchemin, Manu Rangachari, Arnaud Droit, Mickael Leclercq, Gian Filipo Ruda, Muhammad Umair, Asmita Pradeep Yeola, Paul Brennan, Ana C. Anderson, Melanie Alpaugh, Reda Fazazi, Joanie Baillargeon, John B. Williams, Hans Lassmann, Prenitha Mercy Ignatius Arokia Doss, Charles Joly-Beauparlant, Neva J. Fudge, Irshad Akbar, Craig S. Moore
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108833-(2021)
Summary Sex differences in multiple sclerosis (MS) incidence and severity have long been recognized. However, the underlying cellular and molecular mechanisms for why male sex is associated with more aggressive disease remain poorly defined. Using a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4946a2b4e5a3cfd9bc58151cf0087d
https://doi.org/10.1016/j.celrep.2021.108833
https://doi.org/10.1016/j.celrep.2021.108833