Výsledky vyhledávání - "Irsan E. Kooi"

Akademický článek

Loss of photoreceptorness and gain of genomic alterations in retinoblastoma reveal tumor progression

Autor: Irsan E. Kooi, Berber M. Mol, Annette C. Moll, Paul van der Valk, Marcus C. de Jong, Pim de Graaf, Saskia E. van Mil, Antoinette Y.N. Schouten-van Meeteren, Hanne Meijers-Heijboer, Gertjan L. Kaspers, Hein te Riele, Jacqueline Cloos, Josephine C. Dorsman

Publikováno v: EBioMedicine, Vol 2, Iss 7, Pp 660-670 (2015)

Background: Retinoblastoma is a pediatric eye cancer associated with RB1 loss or MYCN amplification (RB1+/+MYCNA). There are controversies concerning the existence of molecular subtypes within RB1−/− retinoblastoma. To test whether these molecula

Externí odkaz: https://doaj.org/article/db54bfbc068f4183bfb31b53cfcb3035

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Supplemetal Material and Methods, Figure 1-7 and Table 1 from Defects in the Fanconi Anemia Pathway and Chromatid Cohesion in Head and Neck Cancer

Autor: Ruud H. Brakenhoff, Stephan M. Feller, Hans Joenje, Bauke Ylstra, Jesper A. Balk, Ralf Dietrich, Arjen Brink, Saskia E. van Mil, Martin A. Rooimans, Anneke B. Oostra, Irsan E. Kooi, Petra van der Lelij, Najim Ameziane, Chantal Stoepker

Supplemental Material and Methods. Supplemental Figure S1. Cell cycle analysis in FA and sporadic HNSCC cell lines upon ICL treatment. Supplemental Figure S2. FANCM protein expression is absent in FaDu cells. Supplemental Figure S3. Overview of possi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3787e8371329b3552a21a7e7c61e5949
https://doi.org/10.1158/0008-5472.22405466

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Akademický článek

A Meta-Analysis of Retinoblastoma Copy Numbers Refines the List of Possible Driver Genes Involved in Tumor Progression.

Autor: Irsan E Kooi, Berber M Mol, Maarten P G Massink, Marcus C de Jong, Pim de Graaf, Paul van der Valk, Hanne Meijers-Heijboer, Gertjan J L Kaspers, Annette C Moll, Hein Te Riele, Jacqueline Cloos, Josephine C Dorsman

Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0153323 (2016)

BACKGROUND:While RB1 loss initiates retinoblastoma development, additional somatic copy number alterations (SCNAs) can drive tumor progression. Although SCNAs have been identified with good concordance between studies at a cytoband resolution, accura

Externí odkaz: https://doaj.org/article/a4e101cc4a1d4a9ebfd3f8e89c61b4f4

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Genomic cfDNA Analysis of Aqueous Humor in Retinoblastoma Predicts Eye Salvage: The Surrogate Tumor Biopsy for Retinoblastoma

Autor: Bibiana J. Reiser, David Cobrinik, Thomas C. Lee, Jonathan W. Kim, Mark W. Reid, Peter Kuhn, Lisa Welter, James W. Hicks, Bao Han A. Le, Patricia Chévez-Barrios, Kevin Stachelek, A. Linn Murphree, Liya Xu, Irsan E. Kooi, Jesse L. Berry, Rima Jubran, Rishvanth K. Prabakar

Publikováno v: Molecular Cancer Research. 16:1701-1712

Tumor-derived cell-free DNA (cfDNA) has biomarker potential; therefore, this study aimed to identify cfDNA in the aqueous humor (AH) of retinoblastoma eyes and correlate somatic chromosomal copy-number alterations (SCNA) with clinical outcomes, speci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6292f36bbaf1775ef7b816bcd2af90d3
https://doi.org/10.1158/1541-7786.mcr-18-0369

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Non-invasive tumor genotyping using radiogenomic biomarkers, a systematic review and oncology-wide pathway analysis

Autor: Catharina W Menke-van der Houven van Oordt, Adrianus J. de Langen, Marcus C. de Jong, Jonas A. Castelijns, Roland M. Martens, Josephine C. Dorsman, Irsan E. Kooi, Pim de Graaf, B.H.E. Jansen, Paul van Amstel, Robin W. Jansen, Annette C. Moll, Pieter Wesseling

Publikováno v: Jansen, R W, van Amstel, P, Martens, R M, Kooi, I E, Wesseling, P, de Langen, A J, van Oordt, C W M V D H, Jansen, B H E, Moll, A C, Dorsman, J C, Castelijns, J A, de Graaf, P & de Jong, M C 2018, ' Non-invasive tumor genotyping using radiogenomic biomarkers, a systematic review and oncology-wide pathway analysis ', Oncotarget, vol. 9, no. 28, pp. 20134-20155 . https://doi.org/10.18632/oncotarget.24893
Oncotarget

With targeted treatments playing an increasing role in oncology, the need arises for fast non-invasive genotyping in clinical practice. Radiogenomics is a rapidly evolving field of research aimed at identifying imaging biomarkers useful for non-invas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea704681e258be1d77366e23c143e26d
https://doi.org/10.18632/oncotarget.24893

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Genomic landscape of retinoblastoma inRb−/−p130−/−mice resembles human retinoblastoma

Autor: Josephine C. Dorsman, Gertjan J.L. Kaspers, Saskia E. van Mil, Jacqueline Cloos, Berber M. Mol, David MacPherson, Annette C. Moll, Hanne Meijers-Heijboer, Irsan E. Kooi, Hein te Riele

Publikováno v: Genes, Chromosomes and Cancer. 56:231-242

Several murine retinoblastoma models have been generated by deleting the genes encoding for retinoblastoma susceptibility protein pRb and one of its family members p107 or p130. In Rb-/- p107-/- retinoblastomas, somatic copy number alterations (SCNAs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94e8ad957eb4212854804e565137a9f6
https://doi.org/10.1002/gcc.22429

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Diagnostic yield of a targeted gene panel in primary ciliary dyskinesia patients

Autor: Erik A. Sistermans, Hans W.M. Niessen, Hans Daniels, Youssef Moutaouakil, Irsan E. Kooi, Tamara Paff, Eric G. Haarman, Gerard Pals, Elise Riesebos, Janneke Marjan Weiss, Dimitra Micha

Publikováno v: Human Mutation, 39(5), 653-665. Wiley-Liss Inc.
Paff, T, Kooi, I E, Moutaouakil, Y, Riesebos, E, Sistermans, E A, Daniels, H J M A, Weiss, J M M, Niessen, H H W M, Haarman, E G, Pals, G & Micha, D 2018, ' Diagnostic yield of a targeted gene panel in primary ciliary dyskinesia patients ', Human Mutation, vol. 39, no. 5, pp. 653-665 . https://doi.org/10.1002/humu.23403

We aimed to determine the diagnostic yield of a targeted-exome panel in a cohort of 74 Dutch primary ciliary dyskinesia (PCD) patients. The panel consisted of 26 PCD-related and 284 candidate genes. To prioritize PCD candidate genes, we investigated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48fbbe59841cc7dc0307a97c8018141b
https://research.vumc.nl/en/publications/de1b085c-d0fd-4a53-b7ff-aa244b09728a

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MR imaging features of retinoblastoma : Association with gene expression profiles

Autor: Sophia Göricke, Josephine C. Dorsman, Philippe Maeder, Irsan E. Kooi, Paolo Galluzzi, Jonas A. Castelijns, Robin W. Jansen, Selma Sirin, Marcus C. de Jong, Jacqueline Cloos, Paul van der Valk, Annette C. Moll, Pim de Graaf, Iris Eekhout, Hervé Brisse

Publikováno v: Radiology, 288(2), 506-515. Radiological Society of North America Inc.
Jansen, R W, de Jong, M C, Kooi, I E, Sirin, S, Göricke, S, Brisse, H J, Maeder, P, Galluzzi, P, van der Valk, P, Cloos, J, Eekhout, I, Castelijns, J A, Moll, A C, Dorsman, J C & de Graaf, P 2018, ' MR Imaging Features of Retinoblastoma : Association with Gene Expression Profiles ', Radiology, vol. 288, no. 2, pp. 506-515 . https://doi.org/10.1148/radiol.2018172000

Purpose To identify associations between magnetic resonance (MR) imaging features and gene expression in retinoblastoma. Materials and Methods A retinoblastoma MR imaging atlas was validated by using anonymized MR images from referral centers in Esse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce82e1efbcb2098f4515870c9be9c77a
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85050352203

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