Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Irreversible Toxicity"'
Publikováno v:
Egyptian Journal of Basic and Applied Sciences. 6:10-24
Doxorubicin (DXR) is a broad-spectrum anti-cancer. Doxorubicin irreversible toxicity resulting from oxidative damage limits its therapeutic use. Boswellic acids (BAs) are inhibitors of 5-lipoxygena...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35163e67bb37fdebc75ed4678aca84c9
https://doi.org/10.1080/2314808x.2019.1586359
https://doi.org/10.1080/2314808x.2019.1586359
Autor:
Bo Wang, Debmalya Roy, Muhammad Farooq, Brobbey Emmanuel, Aquib, Zahid Hussain, Qurat Ul Ain, Anam Ahsan
Publikováno v:
Emerging Contaminants and Associated Treatment Technologies ISBN: 9783030459222
Endocrine-disrupting chemicals can be described as exogenous factors that impede the production, release, circulation, and binding of the body’s endogenous hormones, essential for the continuation of reproduction, growth, and homeostasis. In the pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc24cf60ac31e3fe0333f12c59605dbf
https://doi.org/10.1007/978-3-030-45923-9_7
https://doi.org/10.1007/978-3-030-45923-9_7
Autor:
Sameer N. Goyal, Dharamvir Singh Arya, Umesh B Mahajan, Shreesh Ojha, Chandrgouda R. Patil, Mohanraj Rajesh, Hasan Al Taee
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2016 (2016)
Oxidative Medicine and Cellular Longevity, Vol 2016 (2016)
Doxorubicin (DOX) is a potent and widely used anthracycline antibiotic for the treatment of several malignancies. Unfortunately, the clinical utility of DOX is often restricted due to the elicitation of organ toxicity. Particularly, the increased ris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18474fa13e56cad2b06dfc86bd4c0e3c
http://europepmc.org/articles/PMC4893565
http://europepmc.org/articles/PMC4893565
Autor:
Nathan Fischel-Ghodsian
Publikováno v:
Annals of the New York Academy of Sciences. 884:99-109
Ototoxicity is the major irreversible toxicity of aminoglycosides, and occurs both in a dose-dependent and idiosyncratic fashion. The idiosyncratic pathway is presumably due to genetic predispositions, and in 1993 we identified an inherited mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1f3c68af51c54b5b609bb1332d9ae4
https://doi.org/10.1111/j.1749-6632.1999.tb08639.x
https://doi.org/10.1111/j.1749-6632.1999.tb08639.x
Publikováno v:
Comparative biochemistry and physiology. Toxicologypharmacology : CBP. 161
This study evaluated irreversible toxicity effects of gold nanoparticles (AuNPs) during the short-term (only embryonic stage) and long-term (both embryo and sac-fry stages) exposures of Japanese ricefish, Oryzias latipes (medaka) embryos and sac-fry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4551ff2741f9f430d8db944b78aa47
https://pubmed.ncbi.nlm.nih.gov/24440878
https://pubmed.ncbi.nlm.nih.gov/24440878
Publikováno v:
Leukemia Research. 17:397-401
Methylglyoxal (2-oxopropanal) is the physiological substrate of the glyoxalase system. When exogenous methylglyoxal (50 microM-1 mM) was added to human leukaemia 60 (HL60) cells in culture (5 x 10(4) cells/ml), inhibition of growth and toxicity was i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce60989e0c0152ac2e6e52ef9aa9c65
https://doi.org/10.1016/0145-2126(93)90094-2
https://doi.org/10.1016/0145-2126(93)90094-2
Publikováno v:
Biotechnology and Bioengineering 79 (2002) 3
Biotechnology and Bioengineering, 79(3), 314-322
Biotechnology and Bioengineering, 79(3), 314-322
An unadapted mixed methanogenic sludge transformed formaldehyde into methanol and formate. The methanol to formate ratio obtained was 1:1. Formaldehyde conversion proceeded without any lag phase, suggesting the constitutive character of the formaldeh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d87a840652d8b60cf24367ced0c552
https://pubmed.ncbi.nlm.nih.gov/12115420
https://pubmed.ncbi.nlm.nih.gov/12115420
Publikováno v:
Waste minimisation and end of pipe treatment in chemical and petrochemical industries : proceedings of the IAWQ International Specialised Conference of the Chemical Industry Group. Merida, Yucatan, Mexico, November 14-18, 1999 / G. Buitron, H.Macarie (eds.).-Merida, Yucatan, Mexico : IAWQ, 1999
Water Science and Technology, 42, 223-229
Water Science and Technology 42 (2000)
Water Science and Technology, 42, 223-229
Water Science and Technology 42 (2000)
Formaldehyde toxicity during acetoclastic methanogenesis exerted a dual character: It was in part reversible and in part irreversible. Toxicity was only reversible at very low formaldehyde concentration. The degree of irreversible toxicity was propor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30aea7d1a3758f0edee29b1b4fbf15b8
https://research.wur.nl/en/publications/formaldehyde-toxicity-in-anaerobic-systems-2
https://research.wur.nl/en/publications/formaldehyde-toxicity-in-anaerobic-systems-2
Autor:
Harold Boxenbaum
Publikováno v:
Archives of gerontology and geriatrics. 13(2)
The hazard function, denoted h(x), is the probability of death during an interval of time [Formula: see text], assuming survival to the beginning of the interval. Brues and Sacher provided both theoretical and experimental support for the assumption
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05bed0487585515007cfd937125238a2
https://pubmed.ncbi.nlm.nih.gov/15374423
https://pubmed.ncbi.nlm.nih.gov/15374423
Autor:
Anthony D. Elias
Publikováno v:
Clinical Orthopaedics and Related Research. 289:94
Single-agent and combination chemotherapy have greater than 20% single-agent activity: doxorubicin and ifosfamide. Certain other anthracycline analogues possess similar activity. It remains a question whether combination therapy is any better than si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46800a94affd3095456b603d3d66e10a
https://doi.org/10.1097/00003086-199304000-00012
https://doi.org/10.1097/00003086-199304000-00012