Zobrazeno 1 - 10
of 3 578
pro vyhledávání: '"Iron transport"'
Autor:
Zhuoying Yang, Zehao Zhou, Qingyu Meng, Zhijie Chen, Liang Yun, Jianjun Jiang, Yujing He, Meijuan Dian, Ruihao Zhang, Haotian Ge, Tianbao Yan, Biying Men, Zichao Li, Xu Wu, Junming He, Shuan Rao
Publikováno v:
Cancer Medicine, Vol 13, Iss 19, Pp n/a-n/a (2024)
ABSTRACT Background Despite significant advances in lung cancer treatment, cisplatin (DDP)‐based chemotherapy remains a cornerstone for managing the disease. However, the prevalence of chemoresistance presents a major challenge, limiting its effect
Externí odkaz:
https://doaj.org/article/9f55a898b7354e5c83c603c94cd0e45d
Autor:
Valerio Secli, Emma Michetti, Francesca Pacello, Federico Iacovelli, Mattia Falconi, Maria Luisa Astolfi, Daniela Visaggio, Paolo Visca, Serena Ammendola, Andrea Battistoni
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Limiting the availability of transition metals at infection sites serves as a critical defense mechanism employed by the innate immune system to combat microbial infections. Pseudomonas aeruginosa exhibits a remarkable ability to thrive in z
Externí odkaz:
https://doaj.org/article/42842d08acb14d8e804bf61e9b8c395c
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Background Vascular calcification (VC) is an independent risk factor for cardiovascular diseases. Recently, ferroptosis has been recognised as a novel therapeutic target for cardiovascular diseases. Although an association between ferroptosi
Externí odkaz:
https://doaj.org/article/d6b8ee64d19f44198562441047d1dcd5
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Understanding how bacteria adapt to different environmental conditions is crucial for advancing knowledge regarding pathogenic mechanisms that operate during infection as well as efforts to develop new therapeutic strategies to cure or preve
Externí odkaz:
https://doaj.org/article/bb2ccfc2c91643afbac9232e87024e21
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
The iron transport system plays a crucial role in the extracellular electron transfer process of Shewanella sp. In this study, we fabricated a vertically oriented α-Fe2O3 nanoarray on carbon cloth to enhance interfacial electron transfer in Shewanel
Externí odkaz:
https://doaj.org/article/aa048a494bf745a8890b62e2ea825297
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
We studied the Escherichia coli outer membrane protein Fiu, a presumed transporter of monomeric ferric catecholates, by introducing Cys residues in its surface loops and modifying them with fluorescein maleimide (FM). Fiu-FM bound iron complexes of t
Externí odkaz:
https://doaj.org/article/251b280807874e81b191f2004fc73118
Autor:
Zhusheng Feng, Yingnan Fan, Xiaofei Shi, Xu Luo, Jiangang Xie, Shanshou Liu, Chujun Duan, Qianmei Wang, Yuqin Ye, Wen Yin
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27000- (2024)
Objective: The early targeted and effective diagnosis and treatment of severe trauma are crucial for patients' outcomes. Blood leukocytes act as significant effectors during the initial inflammation and activation of innate immunity in trauma. This s
Externí odkaz:
https://doaj.org/article/66c51d12deaa497a8b6752be010c1249
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity, Vol Volume 16, Pp 3235-3247 (2023)
Ji-Ren An,1,2,* Qing-Feng Wang,1,* Gui-Yan Sun,1 Jia-Nan Su,1 Jun-Tong Liu,1 Chi Zhang,1 Li Wang,1 Dan Teng,3 Yu-Feng Yang,1 Yan Shi1 1Liaoning Key Laboratory of Chinese Medicine Combining Disease and Syndrome of Diabetes, Liaoning University
Externí odkaz:
https://doaj.org/article/4923cdca70164e8b8107bd03426157ee
Akademický článek
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Autor:
Vivien Canran Luo, Mark W. Peczuh
Publikováno v:
Molecules, Vol 29, Iss 16, p 3889 (2024)
This review strives to assemble a set of molecular design principles that enables the delivery of antibiotic warheads to Gram-negative bacterial targets (ESKAPE pathogens) using iron-chelating siderophores, known as the Trojan Horse strategy for anti
Externí odkaz:
https://doaj.org/article/e2f610cf4cf8421e91dbf8a1d007e1ce