Výsledky vyhledávání - "Irminger, J.C."

Reg1 and Reg3β expression in the pancreas of adult diabetic Goto-Kakizaki rats

Autor: Giroix, M.H., Calderari, Sophie, Irminger, J.C., Ehses, J.A., Coulaud, J., Rickenbach, K., Serradas, Patricia, Homo-Delarche, Françoise

Publikováno v: 47. Annual Meeting of the European-Association for the Study of Diabetes
47. Annual Meeting of the European-Association for the Study of Diabetes, Sep 2011, Lisbonne, Portugal. Springer, Diabetologia, 54 (S1), 542 p., 2011, 47th Annual Meeting of the European Association for the Study of Diabetes

International audience; Reg protein expression is associated with islet development, β-cell damage, diabetes and pancreatitis. We previously reported that islets of 4-month-old (4-mo) Goto-Kakizaki (GK) rats, a spontaneous model of type 2 diabetes,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::23a27bfeb0b57e243968464e51fd3a13
https://hal.inrae.fr/hal-02748780

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Reg1 and Reg3β expression in the pancreas of adult diabetic Goto-Kakizaki (GK) rats

Autor: Irminger, J.C., Giroix, M.H., Calderari, Sophie, Ehses, Jan, Coulaud, J., Rickenbah, K., Serradas, Patricia, Homo-Delarche, Françoise

Publikováno v: Annual Meeting of the American-Society-for-Cell-Biology
Annual Meeting of the American-Society-for-Cell-Biology, Dec 2011, Denver, United States. The American Society for Cell Biology, Molecular Biology of the Cell, 22, 217 p., 2011, Late Abstracts, 2011 Annual Meeting ASCB

International audience; Reg protein expression is associated with islet development, β-cell damage, diabetes and pancreatitis. We previously reported that islets of 4-month-old (4-mo) GK rats, a spontaneous model of type 2 diabetes, overexpress Reg1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c8ce180cdd0257d94f4116975488828a
https://hal.inrae.fr/hal-02747763

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Defective pancreas vascularisation and downregulation of soluble epoxyde hydrolase gene expression in various organs in Goto-Kakizaki (GK) foetuses

Autor: Giroix, M.H., Irminger, J.C., Calderari, Sophie, Schmidlin, F., Lacraz, Grégory, Cornut, M., Coulaud, J., Kergoat, M., Homo-Delarche, Françoise

Publikováno v: 45. Annual Meeting of the European Association for the Study of Diabetes
45. Annual Meeting of the European Association for the Study of Diabetes, Sep 2009, Vienne, Austria. Springer Link, Diabetologia, 52 (S1), 550 p., 2009, 45th EASD Annual Meeting of the European Association for the Study of Diabetes

International audience; We identified islet inflammation associated with microangiopathy in diabetic GK rats (a spontaneous model of T2D). Signs of islet microangiopathy are also present in prediabetic 1-week-old GK neonates (1-w-GK), together with i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3f10ea847795a98ac7a57f772b8c3331
https://hal.inrae.fr/hal-02756377

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The prediabetic period is characterized by islet microangiopathy in the Goto-Kakizaki rat, a spontaneous model of type 2 diabetes

Autor: Homo-Delarche, Françoise, Giroix, M.H., Lacraz, G., Calderari, Sophie, Cornut, M., Ehses, J.A., Schmidlin, F., Coulaud, J., Gangnerau, M.N., Serradas, P., Irminger, J.C.

Publikováno v: 44. EASD Annual Meeting of the European Association for the Study of Diabetes
44. EASD Annual Meeting of the European Association for the Study of Diabetes, Sep 2008, Rome, Italy. Springer, Diabetologia, 51 (S1), 588 p., 2008, 44th EASD Annual Meeting of the European Association for the Study of Diabetes

International audience; Endothelial signals are essential during pancreas development. Goto-Kakizaki (GK) rats have a 70% decrease in β-cell mass at E18, while it is similar at E13 to that of Wistar control rats. Because adult diabetic GK rats are h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e015c61f739ea7662ec6753cb9e1c6ca
https://hal.inrae.fr/hal-02755329

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Inflammation and fibrosis on the Islets of Langerhans in the Goto-Kakizaki (GK) rat, spontaneous model of DT2: reflection of an insular microangiopathy?

Autor: Homo-Delarche, Françoise, Calderari, Sophie, Irminger, J.C., Coulaud, J., Gangnerau, Marie-Noëlle, Rickenbach, K., Halban, Philippe, Portha, B., Serradas, Patricia

Publikováno v: Diabetes and Metabolism
Congrés Annuel de l'ALFEDIAM
Congrés Annuel de l'ALFEDIAM, Société Francophone du Diabète (SFD). FRA., Mar 2006, Paris, France

National audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6605173bdabcb3793a70f1dd80af6807
https://hal.inrae.fr/hal-02756013

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Overexpression of regenerative, antioxidant and inflammatory genes in adult diabetic GK islets

Autor: Serradas, Patricia, Irminger, J.C., Gangnerau, Marie-Noëlle, Calderari, Sophie, Rickenbach, K., Halban, P.A., Portha, B.

Publikováno v: 18. Congress of the International Diabetes Federation
18. Congress of the International Diabetes Federation, Aug 2003, Paris, France. Springer Verlag, Diabetologia, 46 (S2), 443 p., 2003, IDF Congress 2003

National audience; In the adult GK rat, a spontaneous model of type 2 diabetes, total pancreatic β-cell number is decreased by 60%. This alteration cannot be ascribed to increased β-cell apoptosis but is related to decreased β-cell replication. Mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3e3fe03b6c2dbb4bbbdd2a781c1aed59
https://hal.inrae.fr/hal-02763025

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