Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Irmgard U, Haussmann"'
Autor:
Pinar Ustaoglu, David W. J. McQuarrie, Anthony Rochet, Thomas C. Dix, Irmgard U. Haussmann, Roland Arnold, Jean-Marc Devaud, Matthias Soller
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2024)
Down syndrome cell adhesion molecule (Dscam) gene encodes a cell adhesion molecule required for neuronal wiring. A remarkable feature of arthropod Dscam is massive alternative splicing generating thousands of different isoforms from three variable cl
Externí odkaz:
https://doaj.org/article/fd81551ee6684cafa512de51b39b6095
Autor:
Irmgard U. Haussmann, Yanying Wu, Mohanakarthik P. Nallasivan, Nathan Archer, Zsuzsanna Bodi, Daniel Hebenstreit, Scott Waddell, Rupert Fray, Matthias Soller
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The two cap methyltransferases (CMTrs) redundantly methylate riboses of first cap adjacent nucleotides in messenger RNAs in Drosophila. Here, CMTrs are required for reward learning and localization of untranslated messenger RNAs to synapses.
Externí odkaz:
https://doaj.org/article/9ddea6fc816144ce8ba3edac4847c01c
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Female reproductive behaviors and physiology change profoundly after mating. The control of pregnancy-associated changes in physiology and behaviors are largely hard-wired into the brain to guarantee reproductive success, yet the
Externí odkaz:
https://doaj.org/article/10d6db4affd843feb001baa2e582cc62
Autor:
Pinar Ustaoglu, Jatinder Kaur Gill, Nicolas Doubovetzky, Irmgard U. Haussmann, Thomas C. Dix, Roland Arnold, Jean-Marc Devaud, Matthias Soller
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Ustaoglu, Gill, et al. investigate the role of the single copy of the elav/Hu family gene in honeybees in learning and memory. RNAi knockdown of elavl2 demonstrates a role in learning and memory, and ELAVL2 is dynamically expressed with altered alter
Externí odkaz:
https://doaj.org/article/d2f1b9e7530a4a599e45c422dcff30ce
Autor:
Praveen Bawankar, Tina Lence, Chiara Paolantoni, Irmgard U. Haussmann, Migle Kazlauskiene, Dominik Jacob, Jan B. Heidelberger, Florian M. Richter, Mohanakarthik P. Nallasivan, Violeta Morin, Nastasja Kreim, Petra Beli, Mark Helm, Martin Jinek, Matthias Soller, Jean-Yves Roignant
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The E3 ligase Hakai can interact with the m6A methylation machinery but its function is still unclear. Here, the authors show that Hakai is a conserved component of the m6A methyltransferase complex and provide functional and molecular insights into
Externí odkaz:
https://doaj.org/article/fecec708c84b4bd4904def2c94ce32a6
Autor:
Marzia Munafò, Victoria R Lawless, Alessandro Passera, Serena MacMillan, Susanne Bornelöv, Irmgard U Haussmann, Matthias Soller, Gregory J Hannon, Benjamin Czech
Publikováno v:
eLife, Vol 10 (2021)
The nuclear pore complex (NPC) is the principal gateway between nucleus and cytoplasm that enables exchange of macromolecular cargo. Composed of multiple copies of ~30 different nucleoporins (Nups), the NPC acts as a selective portal, interacting wit
Externí odkaz:
https://doaj.org/article/6b6faff476fb481f814cc489979dcd57
Autor:
Thomas C. Dix, Irmgard U. Haussmann, Sarah Brivio, Mohannakarthik P. Nallasivan, Yavor HadzHiev, Ferenc Müller, Berndt Müller, Jonathan Pettitt, Matthias Soller
Publikováno v:
RNA. 28:1377-1390
Cap methyltransferases (CMTrs) O methylate the 2′ position of the ribose (cOMe) of cap-adjacent nucleotides of animal, protist, and viral mRNAs. Animals generally have two CMTrs, whereas trypanosomes have three, and many viruses encode one in their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64925970f0bbb32803cb1e0bcd79b17e
https://doi.org/10.1261/rna.079317.122
https://doi.org/10.1261/rna.079317.122
Autor:
Irmgard U. Haussmann, Thomas C. Dix, Veronica Dezi, Abdullah I. Hans, Roland Arnold, Matthias Soller
SUMMARYSingle guide RNA (sgRNA) directs Cas9 nuclease for gene-specific scission of double-stranded DNA. High Cas9 activity is essential for efficient gene editing to generate gene deletions and gene replacements by homologous recombination. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00cfd65b600ee5adb9f846da79acca80
https://doi.org/10.1101/2022.12.15.520550
https://doi.org/10.1101/2022.12.15.520550
Autor:
Thomas C, Dix, Irmgard U, Haussmann, Sarah, Brivio, Mohannakarthik P, Nallasivan, Yavor, HadzHiev, Ferenc, Müller, Berndt, Müller, Jonathan, Pettitt, Matthias, Soller
Publikováno v:
RNA (New York, N.Y.). 28(10)
Cap methyltransferases (CMTrs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f82908254a434b45540b1aac928fe3dc
https://pubmed.ncbi.nlm.nih.gov/35970556
https://pubmed.ncbi.nlm.nih.gov/35970556
Autor:
Matthias Soller, Daniel Hebenstreit, Irmgard U. Haussmann, Zsuzsanna Bodi, Rupert G. Fray, Yin-Hu Wu, Nathan Archer, Scott Waddell, Mohanakarthik Ponnadai Nallasivan
Cap-adjacent nucleotides of animal, protist and viral mRNAs can be O-methylated at the 2‘ position of the ribose (cOMe). The functions of cOMe in animals, however, remain largely unknown. Here we show that the two cap methyltransferases (CMTr1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f0bcfcc3b4695f894f02c182da42eb