Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Irmeli, Roine"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Although rarely reported, bilateral loss of vision is a severe complication of childhood bacterial meningitis. We assessed its frequency in five prospective treatment trials performed in Europe, Latin America, and Angola in 1984–2017. Cour
Externí odkaz:
https://doaj.org/article/5dc7a0af22ac4bf38eba93f601fb4d00
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Our objective was to explore the importance of underweight on the course of childhood bacterial meningitis (BM) at different study sites, because prior studies showed discrepant results. Using directly comparable, prospective data from three
Externí odkaz:
https://doaj.org/article/c745c6e425b04eba8327b3a87c8bc1ce
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Our objective was to quantify the differences in the outcomes from childhood bacterial meningitis (BM) and to describe the factors associated with them in different parts of the world. This study is a secondary analysis of prospectively coll
Externí odkaz:
https://doaj.org/article/460814bdad39410ea087b7d47e728f7a
Publikováno v:
International Journal of Infectious Diseases, Vol 106, Iss , Pp 223-227 (2021)
Background: Yearly, about two million infants die during the first 28 days of life. Most of these deaths occur in sub-Saharan Africa and a third of those are caused by severe infections. The early identification of infants at risk of death is importa
Externí odkaz:
https://doaj.org/article/b4fd099953cc42b79e882e5699b4a5c2
Autor:
Tuula Pelkonen, Suvi Urtti, Elizabete dos Anjos, Ondina Cardoso, Linda de Gouveia, Irmeli Roine, Heikki Peltola, Anne von Gottberg, Moe H. Kyaw
Publikováno v:
International Journal of Infectious Diseases, Vol 97, Iss , Pp 251-257 (2020)
Background: Despite effective antibiotics and vaccines, bacterial meningitis (BM) remains one of the leading causes of morbidity and mortality in young infants worldwide. Data from Africa on the aetiology and antibiotic susceptibility are scarce. Obj
Externí odkaz:
https://doaj.org/article/9d79753dda394552852e9a908261ff5c
Publikováno v:
BMJ Open, Vol 12, Iss 3 (2022)
Objectives To describe the prevalence and severity of anaemia and to examine its associations with outcome in children with bacterial meningitis (BM).Design Secondary analysis of descriptive data from five randomised BM treatment trials.Setting Hospi
Externí odkaz:
https://doaj.org/article/7a5591bc82384c5c8220d400475e8f3a
Autor:
Emilie Rugemalira, Irmeli Roine, Julia Kuligowski, Ángel Sánchez-Illana, José David Piñeiro-Ramos, Sture Andersson, Manuel Leite Cruzeiro, Máximo Vento, Tuula Pelkonen
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 621 (2023)
Neuronal damage in bacterial meningitis (BM) partly stems from the host´s inflammatory response and induced oxidative stress (OS). We studied the association of cerebrospinal fluid (CSF) biomarkers indicating oxidative damage to proteins with course
Externí odkaz:
https://doaj.org/article/8e55282493254ea3968cbe1bf7c18824
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 108:851-856
In areas with suboptimal resources, blood transfusion may not be feasible even when mandatory for severely anemic children with a life-threatening disease. We evaluated how much not having received a transfusion affected the survival in 171 children
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7622fad07444a302c2c5a915147870d
https://doi.org/10.4269/ajtmh.22-0650
https://doi.org/10.4269/ajtmh.22-0650
Autor:
Okko Savonius, Irmeli Roine, Saeed Alassiri, Taina Tervahartiala, Otto Helve, Josefina Fernández, Heikki Peltola, Timo Sorsa, Tuula Pelkonen
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Background. Matrix metalloproteinases (MMPs) and myeloperoxidase (MPO) contribute to the inflammatory cascade in the cerebrospinal fluid (CSF) during bacterial meningitis. We determined levels of MPO, MMP-8, MMP-9, and tissue inhibitor of metalloprot
Externí odkaz:
https://doaj.org/article/2053feb66b104fe596e16512943bf9f9
Publisher Copyright: Copyright © 2022 The Author(s). Sickle cell disease (SCD) was found in 10% of children with bacterial meningitis (BM) in Luanda, 5-fold more than in the general population. BM children with SCD versus BM children without SCD had
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34af581d86b71a8cac093ec92967354e
http://hdl.handle.net/10138/346687
http://hdl.handle.net/10138/346687
