Zobrazeno 1 - 10
of 277
pro vyhledávání: '"Irma Thesleff"'
Autor:
Ana-Marija Sulic, Rishi Das Roy, Verdiana Papagno, Qiang Lan, Riikka Saikkonen, Jukka Jernvall, Irma Thesleff, Marja L. Mikkola
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112643- (2023)
Summary: Morphogenesis of ectodermal organs, such as hair, tooth, and mammary gland, starts with the formation of local epithelial thickenings, or placodes, but it remains to be determined how distinct cell types and differentiation programs are esta
Externí odkaz:
https://doaj.org/article/d376cbf43e3543e89035159addf00af1
Autor:
Thomas Imhof, Anamaria Balic, Juliane Heilig, Ruth Chiquet-Ehrismann, Matthias Chiquet, Anja Niehoff, Bent Brachvogel, Irma Thesleff, Manuel Koch
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
The continuously growing mouse incisor provides a fascinating model for studying stem cell regulation and organ renewal. In the incisor, epithelial and mesenchymal stem cells assure lifelong tooth growth. The epithelial stem cells reside in a niche k
Externí odkaz:
https://doaj.org/article/d0c2b2c403a14339af7ed55f37588675
Autor:
Kan Saito, Frederic Michon, Aya Yamada, Hiroyuki Inuzuka, Satoko Yamaguchi, Emiko Fukumoto, Keigo Yoshizaki, Takashi Nakamura, Makiko Arakaki, Yuta Chiba, Masaki Ishikawa, Hideyuki Okano, Irma Thesleff, Satoshi Fukumoto
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101329- (2020)
Summary: The transcription factor Sox21 is expressed in the epithelium of developing teeth. The present study aimed to determine the role of Sox21 in tooth development. We found that disruption of Sox21 caused severe enamel hypoplasia, regional osteo
Externí odkaz:
https://doaj.org/article/b8f5cb3372324ed98382e503ff281643
Autor:
Tomo Aonuma, Nagato Tamamura, Tomohiro Fukunaga, Yuichi Sakai, Nobuo Takeshita, Shohei Shigemi, Takashi Yamashiro, Irma Thesleff, Teruko Takano-Yamamoto
Publikováno v:
Bone Reports, Vol 12, Iss , Pp 100285- (2020)
Runt-related transcription factor 2 (Runx2) is an essential transcription factor for osteoblast differentiation, and is activated by mechanical stress to promote osteoblast function. Cleidocranial dysplasia (CCD) is caused by mutations of RUNX2, and
Externí odkaz:
https://doaj.org/article/ba30e5fa22c047a394608873f841ebc4
Autor:
Xiu-Ping Wang, Marika Suomalainen, Szabolcs Felszeghy, Laura C Zelarayan, Maria T Alonso, Maksim V Plikus, Richard L Maas, Cheng-Ming Chuong, Thomas Schimmang, Irma Thesleff
Publikováno v:
PLoS Biology, Vol 5, Iss 6, p e159 (2007)
Epithelial stem cells reside in specific niches that regulate their self-renewal and differentiation, and are responsible for the continuous regeneration of tissues such as hair, skin, and gut. Although the regenerative potential of mammalian teeth i
Externí odkaz:
https://doaj.org/article/c670829e8d30498695f162f205898ffe
Autor:
Ana-Marija Sulic, Rishi Das Roy, Verdiana Papagno, Qiang Lan, Riikka Saikkonen, Jukka Jernvall, Irma Thesleff, Marja L Mikkola
SUMMARYMorphogenesis of ectodermal organs, such as hair, tooth, and mammary gland, starts with the formation of local epithelial thickenings, or placodes, but it remains to be determined how distinct cell types and differentiation programs are establ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f8cf6d218f8c1fa9ddef965420121f5
https://doi.org/10.1101/2022.11.03.515012
https://doi.org/10.1101/2022.11.03.515012
Publikováno v:
Calcified Tissue International
Treatment with intravenous bisphosphonate (BP) in children and adolescents with osteogenesis imperfecta (OI) started in Sweden in 1991. No human studies on the role of BP therapy in development of disturbances in tooth mineralization or tooth morphol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f75d0e7ab1107e6a1b3b38afe2f9fb8
https://doi.org/10.1007/s00223-021-00835-2
https://doi.org/10.1007/s00223-021-00835-2
Autor:
Irma Thesleff, Leah C. Biggs, Piotr Chmielarz, Peter J. McKinnon, Anamaria Balic, Martin Binder
Publikováno v:
Stem Cells
Continuous growth of the mouse incisor teeth is due to the life-long maintenance of epithelial stem cells (SCs) in their niche called cervical loop (CL). Several signaling factors regulate SC maintenance and/or their differentiation to achieve organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895673f8a28e8f98eaef1f36c42b7083
https://doi.org/10.1002/stem.3042
https://doi.org/10.1002/stem.3042
Autor:
Masaki Ishikawa, Takashi Nakamura, Hideyuki Okano, Keigo Yoshizaki, Hiroyuki Inuzuka, Kan Saito, Makiko Arakaki, Emiko Fukumoto, Satoko Yamaguchi, Satoshi Fukumoto, Frederic Michon, Aya Yamada, Yuta Chiba, Irma Thesleff
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101329-(2020)
iScience
iScience
Summary The transcription factor Sox21 is expressed in the epithelium of developing teeth. The present study aimed to determine the role of Sox21 in tooth development. We found that disruption of Sox21 caused severe enamel hypoplasia, regional osteop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d0506fbe84f573f566a7dfd131d0cd
http://www.sciencedirect.com/science/article/pii/S2589004220305162
http://www.sciencedirect.com/science/article/pii/S2589004220305162
Autor:
Takashi Yamashiro, Irma Thesleff, Teruko Takano-Yamamoto, Nagato Tamamura, Tomo Aonuma, Tomohiro Fukunaga, Nobuo Takeshita, Yuichi Sakai, Shohei Shigemi
Publikováno v:
Bone Reports, Vol 12, Iss, Pp 100285-(2020)
Bone Reports
Bone Reports
Runt-related transcription factor 2 (Runx2) is an essential transcription factor for osteoblast differentiation, and is activated by mechanical stress to promote osteoblast function. Cleidocranial dysplasia (CCD) is caused by mutations of RUNX2, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f917876e7cd0d58a4991ea2d2c3c29
http://www.sciencedirect.com/science/article/pii/S2352187220300450
http://www.sciencedirect.com/science/article/pii/S2352187220300450