Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Irma B Stowe"'
Autor:
Lieselotte Vande Walle, Irma B Stowe, Pavel Šácha, Bettina L Lee, Dieter Demon, Amelie Fossoul, Filip Van Hauwermeiren, Pedro H V Saavedra, Petr Šimon, Vladimír Šubr, Libor Kostka, Craig E Stivala, Victoria C Pham, Steven T Staben, Sayumi Yamazoe, Jan Konvalinka, Nobuhiko Kayagaki, Mohamed Lamkanfi
Publikováno v:
PLoS Biology, Vol 17, Iss 10, p e3000529 (2019)
[This corrects the article DOI: 10.1371/journal.pbio.3000354.].
Externí odkaz:
https://doaj.org/article/608abbed317f4c6598fe817ed9e170da
Autor:
Lieselotte Vande Walle, Irma B Stowe, Pavel Šácha, Bettina L Lee, Dieter Demon, Amelie Fossoul, Filip Van Hauwermeiren, Pedro H V Saavedra, Petr Šimon, Vladimír Šubrt, Libor Kostka, Craig E Stivala, Victoria C Pham, Steven T Staben, Sayumi Yamazoe, Jan Konvalinka, Nobuhiko Kayagaki, Mohamed Lamkanfi
Publikováno v:
PLoS Biology, Vol 17, Iss 9, p e3000354 (2019)
The nucleotide-binding-domain (NBD)-and leucine-rich repeat (LRR)-containing (NLR) family, pyrin-domain-containing 3 (NLRP3) inflammasome drives pathological inflammation in a suite of autoimmune, metabolic, malignant, and neurodegenerative diseases.
Externí odkaz:
https://doaj.org/article/8bd2f4be33dd49be835f2a73d22da938
Autor:
Juan Zhang, Donghong Yan, Christopher C. Goodnow, Wendy Sandoval, Jian Payandeh, Bettina L. Lee, Qingling Li, Vicky Cho, Irma B. Stowe, Zora Modrusan, Lisa A. Miosge, Min Xu, Rohit Reja, Gözde Ulas, Merone Roose-Girma, Jing Kang, T. Daniel Andrews, Opher S. Kornfeld, Vishva M. Dixit, Karen O'Rourke, Joshua D. Webster, Wyne P. Lee, Brent S. McKenzie, Meredith Sagolla, Nobuhiko Kayagaki, Lucy X. Morris, Edward M. Bertram
Publikováno v:
Nature. 591:131-136
Plasma membrane rupture (PMR) is the final cataclysmic event in lytic cell death. PMR releases intracellular molecules known as damage-associated molecular patterns (DAMPs) that propagate the inflammatory response1-3. The underlying mechanism of PMR,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fd0fd5289574b697ae44372cb38c109
https://doi.org/10.1038/s41586-021-03218-7
https://doi.org/10.1038/s41586-021-03218-7
Autor:
Irma B. Stowe, James T. Koerber, Aaron Gupta, Qui T. Phung, Hoangdung Ho, Jian Payandeh, Yingnan Zhang, Nobuhiko Kayagaki, Corey E. Bakalarski, Jennie R. Lill, Christopher W. Davies
Publikováno v:
Proc Natl Acad Sci U S A
Inflammasomes sense a number of pathogen and host damage signals to initiate a signaling cascade that triggers inflammatory cell death, termed pyroptosis. The inflammatory caspases (1/4/5/11) are the key effectors of this process through cleavage and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00fc40bf582af81719a5c414185f61b
https://doi.org/10.1073/pnas.2018024118
https://doi.org/10.1073/pnas.2018024118
Autor:
Nobuhiko, Kayagaki, Opher S, Kornfeld, Bettina L, Lee, Irma B, Stowe, Karen, O'Rourke, Qingling, Li, Wendy, Sandoval, Donghong, Yan, Jing, Kang, Min, Xu, Juan, Zhang, Wyne P, Lee, Brent S, McKenzie, Gözde, Ulas, Jian, Payandeh, Merone, Roose-Girma, Zora, Modrusan, Rohit, Reja, Meredith, Sagolla, Joshua D, Webster, Vicky, Cho, T Daniel, Andrews, Lucy X, Morris, Lisa A, Miosge, Christopher C, Goodnow, Edward M, Bertram, Vishva M, Dixit
Publikováno v:
Nature. 591(7848)
Plasma membrane rupture (PMR) is the final cataclysmic event in lytic cell death. PMR releases intracellular molecules known as damage-associated molecular patterns (DAMPs) that propagate the inflammatory response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99a21a561390a8ed6124a54ef201cc30
https://pubmed.ncbi.nlm.nih.gov/33798414
https://pubmed.ncbi.nlm.nih.gov/33798414
Autor:
Sarah K. Kummerfeld, Trinna L. Cuellar, Bettina L. Lee, Michael Reichelt, Benjamin Haley, Nobuhiko Kayagaki, Irma B. Stowe, Kathleen M. Mirrashidi, Colin K. Watanabe
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
The NLRC4 inflammasome recognizes bacterial flagellin and components of the type III secretion apparatus. NLRC4 stimulation leads to caspase-1 activation followed by a rapid lytic cell death known as pyroptosis. NLRC4 is linked to pathogen-free auto-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d784f62e68048019f1f2d3f6de6cb5a5
http://link.springer.com/article/10.1038/s41598-018-21998-3
http://link.springer.com/article/10.1038/s41598-018-21998-3
Autor:
Nobuhiko, Kayagaki, Bettina L, Lee, Irma B, Stowe, Opher S, Kornfeld, Karen, O'Rourke, Kathleen M, Mirrashidi, Benjamin, Haley, Colin, Watanabe, Merone, Roose-Girma, Zora, Modrusan, Sarah, Kummerfeld, Rohit, Reja, Yafei, Zhang, Vicky, Cho, T Daniel, Andrews, Lucy X, Morris, Christopher C, Goodnow, Edward M, Bertram, Vishva M, Dixit
Publikováno v:
Science signaling. 12(582)
Gasdermin-D (GSDMD) is cleaved by caspase-1, caspase-4, and caspase-11 in response to canonical and noncanonical inflammasome activation. Upon cleavage, GSDMD oligomerizes and forms plasma membrane pores, resulting in interleukin-1β (IL-1β) secreti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f864a078c6903b557ffaf0014385bef7
https://pubmed.ncbi.nlm.nih.gov/31113851
https://pubmed.ncbi.nlm.nih.gov/31113851
Autor:
Christopher C. Goodnow, Zora Modrusan, Irma B. Stowe, Rohit Reja, Bettina L. Lee, Sarah K. Kummerfeld, T. Daniel Andrews, Vishva M. Dixit, Benjamin Haley, Karen O'Rourke, Lucy X. Morris, Edward M. Bertram, Kathleen M. Mirrashidi, Yafei Zhang, Merone Roose-Girma, Nobuhiko Kayagaki, Vicky Cho, Colin K. Watanabe, Opher S. Kornfeld
Publikováno v:
Science Signaling. 12
Gasdermin-D (GSDMD) is cleaved by caspase-1, caspase-4, and caspase-11 in response to canonical and noncanonical inflammasome activation. Upon cleavage, GSDMD oligomerizes and forms plasma membrane pores, resulting in interleukin-1β (IL-1β) secreti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7bfcff7b8e203f4b150307103553171
https://doi.org/10.1126/scisignal.aax4917
https://doi.org/10.1126/scisignal.aax4917
Autor:
Juan Zhang, Aaron Gupta, Søren Warming, Irma B. Stowe, Nobuhiko Kayagaki, Opher S. Kornfeld, Keith R. Anderson, Wyne P. Lee, Bettina L. Lee, Merone Roose-Girma
Publikováno v:
The Journal of Experimental Medicine
Lee et al. generate knock-in mice with critical residues mutated in caspase-11 and GSDMD. This is the first compelling genetic evidence to demonstrate the critical roles of caspase-11 catalytic and auto-proteolytic activities, as well as GSDMD cleava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c7258644d89db74e27c9f2c1128ab8
https://pubmed.ncbi.nlm.nih.gov/30135078
https://pubmed.ncbi.nlm.nih.gov/30135078
Autor:
Lucy X. Morris, Edward M. Bertram, Linda Fitzgerald, Juan Zhang, Nobuhiko Kayagaki, Christopher C. Goodnow, Sarah K. Kummerfeld, Jiansheng Wu, Merone Roose-Girma, Keith R. Anderson, Wyne P. Lee, Peter Liu, Benjamin Haley, Bettina L. Lee, Guy S. Salvesen, Qui T. Phung, Søren Warming, Irma B. Stowe, Jennie R. Lill, Yafei Zhang, Scott J. Snipas, Trinna L. Cuellar, Hong Li, Vishva M. Dixit, Karen O'Rourke
Publikováno v:
Nature. 526:666-671
Intracellular lipopolysaccharide from Gram-negative bacteria including Escherichia coli, Salmonella typhimurium, Shigella flexneri, and Burkholderia thailandensis activates mouse caspase-11, causing pyroptotic cell death, interleukin-1β processing,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa1c4d60b85826fe65ea6994bbbcb741
https://doi.org/10.1038/nature15541
https://doi.org/10.1038/nature15541