Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Irma A. Martínez-Davila"'
Autor:
Luis O. Soto-Rojas, Cecilia Bañuelos, Linda Garces-Ramirez, Claudia Luna-Herrera, Yazmin M. Flores-Martínez, Guadalupe Soto-Rodríguez, Bismark Gatica-García, Francisco E. López-Salas, José Ayala-Dávila, María E. Gutiérrez-Castillo, América Padilla-Viveros, Fidel de la Cruz-López, Irma A. Martínez-Davila, Daniel Martinez-Fong
Publikováno v:
MethodsX, Vol 7, Iss , Pp 100821- (2020)
An animal model, suitable for resembling Parkinson's disease (PD) progress, should show both, motor and non-motor alterations. However, these features have been scarcely evaluated or developed in parkinsonian models induced by neurotoxins. This proto
Externí odkaz:
https://doaj.org/article/3c146b565ba14aeab528179f90c90fa3
Autor:
Irais E. Valenzuela-Arzeta, Luis O. Soto-Rojas, Yazmin M. Flores-Martinez, Karen M. Delgado-Minjares, Bismark Gatica-Garcia, Juan U. Mascotte-Cruz, Porfirio Nava, Omar Emiliano Aparicio-Trejo, David Reyes-Corona, Irma A. Martínez-Dávila, M. E. Gutierrez-Castillo, Armando J. Espadas-Alvarez, Carlos E. Orozco-Barrios, Daniel Martinez-Fong
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4628 (2023)
Whether neuroinflammation leads to dopaminergic nigrostriatal system neurodegeneration is controversial. We addressed this issue by inducing acute neuroinflammation in the substantia nigra (SN) with a single local administration (5 µg/2 µL saline s
Externí odkaz:
https://doaj.org/article/f6d9298c367a44d4b2fcd57e39ed6e6e
Autor:
Isaac Pérez-Segura, Alberto Santiago-Balmaseda, Luis Daniel Rodríguez-Hernández, Adriana Morales-Martínez, Hilda Angélica Martínez-Becerril, Paola A. Martínez-Gómez, Karen M. Delgado-Minjares, Citlaltepetl Salinas-Lara, Irma A. Martínez-Dávila, Magdalena Guerra-Crespo, Francisca Pérez-Severiano, Luis O. Soto-Rojas
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3264 (2023)
Parkinson’s disease (PD) is the most common α-synucleinopathy worldwide. The pathognomonic hallmark of PD is the misfolding and propagation of the α-synuclein (α-syn) protein, observed in post-mortem histopathology. It has been hypothesized that
Externí odkaz:
https://doaj.org/article/dbdc72cb1f004600b29e6c36be6f3aba
Autor:
Luis O. Soto-Rojas, Irma A. Martínez-Dávila, Claudia Luna-Herrera, María E. Gutierrez-Castillo, Francisco E. Lopez-Salas, Bismark Gatica-Garcia, Guadalupe Soto-Rodriguez, María Elena Bringas Tobon, Gonzalo Flores, America Padilla-Viveros, Cecilia Bañuelos, Víctor Manuel Blanco-Alvarez, José Dávila-Ayala, David Reyes-Corona, Linda Garcés-Ramírez, Oriana Hidalgo-Alegria, Fidel De La Cruz-lópez, Daniel Martinez-Fong
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-26 (2020)
Abstract The spreading and accumulation of α-synuclein and dopaminergic neurodegeneration, two hallmarks of Parkinson’s disease (PD), have been faithfully reproduced in rodent brains by chronic, oral administration of β-sitosterol β-D-glucoside
Externí odkaz:
https://doaj.org/article/ad31f508e9b948c3897c1764cde981dc
Autor:
Adriana Morales-Martínez, Paola A. Martínez-Gómez, Daniel Martinez-Fong, Marcos M. Villegas-Rojas, Francisca Pérez-Severiano, Miguel A. Del Toro-Colín, Karen M. Delgado-Minjares, Víctor Manuel Blanco-Alvarez, Bertha Alicia Leon-Chavez, Omar Emiliano Aparicio-Trejo, Mauricio T. Baéz-Cortés, Maria-del-Carmen Cardenas-Aguayo, José Luna-Muñoz, Mar Pacheco-Herrero, Quetzalli D. Angeles-López, Irma A. Martínez-Dávila, Citlaltepetl Salinas-Lara, José Pablo Romero-López, Carlos Sánchez-Garibay, Adolfo R. Méndez-Cruz, Luis O. Soto-Rojas
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11394 (2022)
The α-synucleinopathies constitute a subset of neurodegenerative disorders, of which Parkinson’s disease (PD) is the most common worldwide, characterized by the accumulation of misfolded α-synuclein in the cytoplasm of neurons, which spreads in a
Externí odkaz:
https://doaj.org/article/582d89ba51504c4487ec0c54b6e9e357
Autor:
Claudia Luna-Herrera, Irma A. Martínez-Dávila, Luis O. Soto-Rojas, Yazmin M. Flores-Martinez, Manuel A. Fernandez-Parrilla, Jose Ayala-Davila, Bertha A. León-Chavez, Guadalupe Soto-Rodriguez, Victor M. Blanco-Alvarez, Francisco E. Lopez-Salas, Maria E. Gutierrez-Castillo, Bismark Gatica-Garcia, America Padilla-Viveros, Cecilia Bañuelos, David Reyes-Corona, Armando J. Espadas-Alvarez, Linda Garcés-Ramírez, Oriana Hidalgo-Alegria, Fidel De La Cruz-lópez, Daniel Martinez-Fong
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
Chronic consumption of β-sitosterol-β-D-glucoside (BSSG), a neurotoxin contained in cycad seeds, leads to Parkinson’s disease in humans and rodents. Here, we explored whether a single intranigral administration of BSSG triggers neuroinflammation
Externí odkaz:
https://doaj.org/article/0474752dbbf74b6ebd4ef45a062623d7
Autor:
Karen M. Delgado-Minjares, Daniel Martinez-Fong, Irma A. Martínez-Dávila, Cecilia Bañuelos, M. E. Gutierrez-Castillo, Víctor Manuel Blanco-Alvarez, Maria-del-Carmen Cardenas-Aguayo, José Luna-Muñoz, Mar Pacheco-Herrero, Luis O. Soto-Rojas
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11702 (2021)
Parkinson’s disease (PD) is characterized by four pathognomonic hallmarks: (1) motor and non-motor deficits; (2) neuroinflammation and oxidative stress; (3) pathological aggregates of the α-synuclein (α-syn) protein; (4) neurodegeneration of the
Externí odkaz:
https://doaj.org/article/d402cb1c3197411e954425395eecb767
Autor:
Yazmin M. Flores-Martinez, Manuel A. Fernandez-Parrilla, Jose Ayala-Davila, David Reyes-Corona, Victor M. Blanco-Alvarez, Luis O. Soto-Rojas, Claudia Luna-Herrera, Juan A. Gonzalez-Barrios, Bertha A. Leon-Chavez, Maria E. Gutierrez-Castillo, Irma A. Martínez-Dávila, Daniel Martinez-Fong
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Models of Parkinson’s disease with neurotoxins have shown that microglial activation does not evoke a typical inflammatory response in the substantia nigra, questioning whether neuroinflammation leads to neurodegeneration. To address this issue, th
Externí odkaz:
https://doaj.org/article/9db253425860463ca059a8ea37387a12